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Genetics

D-Index
51
Citations
9028
World Ranking
3869
National Ranking
1672

Overview

Steven J. Sandler is affiliated with the University of Massachusetts Amherst in the United States. Their research primarily focuses on fields related to biochemistry, genetics, and molecular biology, with a significant concentration on molecular biology and genetics within these disciplines.

Their published work extensively covers topics such as DNA repair mechanisms, bacterial genetics and biotechnology, and DNA and nucleic acid chemistry. Additional areas of study include CRISPR and genetic engineering, enzyme structure and function, carcinogens and genotoxicity assessment, and amino acid enzymes and metabolism.

Key publication venues for their research include the Journal of Bacteriology, where they have contributed three papers, as well as Molecular Microbiology with two papers published. Other venues featuring their work are Nucleic Acids Research, Nature Communications, and Genetics.

Recent papers authored or coauthored by Steven J. Sandler include the following:

  • Development of a single-stranded DNA-binding protein fluorescent fusion toolbox, 2020, Nucleic Acids Research
  • Interaction with single-stranded DNA-binding protein localizes ribonuclease HI to DNA replication forks and facilitates R-loop removal, 2020, Molecular Microbiology
  • Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli, 2023, Nature Communications
  • Escherichia coli K-12 has two distinguishable PriA-PriB replication restart pathways, 2021, Molecular Microbiology
  • An Epistasis Analysis of recA and recN in Escherichia coli K-12, 2020, Genetics

Sandler frequently collaborates with several researchers in the field, including James L. Keck, Elizabeth A. Wood, Michael M. Cox, A. Klimova, and Katarzyna Dubiel. Among these, James L. Keck is the most frequent coauthor, with five joint publications.

The scientist's research is characterized by its emphasis on DNA replication and repair processes, particularly within bacterial systems. Their investigations have included the study of single-stranded DNA-binding proteins, replication fork dynamics, and genetic pathways relevant to replication restart mechanisms in Escherichia coli.

Best Publications

  • The importance of repairing stalled replication forks

    Michael M. Cox;Myron F. Goodman;Kenneth N. Kreuzer;David J. Sherratt

  • Development of a genetic system for Geobacter sulfurreducens.

    Maddalena V. Coppi;Ching Leang;Steven J. Sandler;Derek R. Lovley

  • Biochemical and genetic characterization of PpcA, a periplasmic c-type cytochrome in Geobacter sulfurreducens.

    Jon R Lloyd;Ching Leang;Allison L Hodges Myerson;Maddalena V Coppi

  • Role of PriA in replication fork reactivation in Escherichia coli.

    Steven J. Sandler;Kenneth J. Marians

  • Homologous genetic recombination: the pieces begin to fall into place.

    Alvin J. Clark;Steven J. Sandler

  • RadA protein is an archaeal RecA protein homolog that catalyzes DNA strand exchange

    Seitz Em;Brockman Jp;Sandler Sj;Clark Aj

  • Overexpression of archaeal proteins in Escherichia coli

    Rosalind Kim;Steve J. Sandler;Stanley Goldman;Hisao Yokota

  • Physical manipulation of the Escherichia coli chromosome reveals its soft nature

    James Pelletier;Ken Halvorsen;Ken Halvorsen;Bae-Yeun Ha;Raffaella Paparcone

  • Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes.

    M Flodström;B Tyrberg;Decio L. Eizirik;S Sandler

  • Differential Suppression of priA2::kan Phenotypes in Escherichia coli K-12 by Mutations in priA, lexA, and dnaC

    Steven J. Sandler;Hardeep S. Samra;Alvin J. Clark

  • Measurement of SOS expression in individual Escherichia coli K-12 cells using fluorescence microscopy.

    Jesse D. McCool;Edward Long;Joseph F. Petrosino;Hilary A. Sandler

  • Multiple genetic pathways for restarting DNA replication forks in Escherichia coli K-12.

    Steven J. Sandler

  • Evolutionary Comparisons of RecA-Like Proteins Across All Major Kingdoms of Living Organisms

    Volker Brendel;Luciano Brocchieri;Steven J. Sandler;Alvin J. Clark

  • recA-Like Genes From Three Archaean Species with Putative Protein Products Similar to Rad51 and Dmcl Proteins of the Yeast Saccharomyces Cerevisiae

    Steven J. Sandler;Leslie H. Satin;Hardeep S. Samra;Alvin J. Clark

  • Replication fork assembly at recombination intermediates is required for bacterial growth

    Joing Liu;Liewei Xu;Steven J. Sandler;Kenneth J. Marians

  • Structure of the SSB–DNA polymerase III interface and its role in DNA replication

    Aimee H Marceau;Soon Bahng;Shawn C Massoni;Nicholas P George

  • IL-1 receptor antagonist inhibits recurrence of disease after syngeneic pancreatic islet transplantation to spontaneously diabetic non-obese diabetic (NOD) mice

    J O Sandberg;Decio L. Eizirik;S Sandler

  • Long-term effects of cyclosporin A on cultured mouse pancreatic islets

    A. Andersson;H. Borg;A. Hallberg;C. Hellerström

  • Localization of RecA in Escherichia coli K‐12 using RecA–GFP

    Nicholas Renzette;Nathan Gumlaw;Jared T. Nordman;Marlee Krieger

  • Interleukin-1 beta increases the activity of superoxide dismutase in rat pancreatic islets.

    L A Borg;E Cagliero;S Sandler;Nils Welsh

Frequent Co-Authors

Decio L. Eizirik
Decio L. Eizirik Université Libre de Bruxelles
Alvin J. Clark
Alvin J. Clark University of Arizona
Claes Hellerström
Claes Hellerström Uppsala University
Klaus Bendtzen
Klaus Bendtzen Rigshospitalet
Kenneth J. Marians
Kenneth J. Marians Memorial Sloan Kettering Cancer Center
Michael M. Cox
Michael M. Cox University of Wisconsin–Madison
Olle Korsgren
Olle Korsgren Uppsala University
Derek R. Lovley
Derek R. Lovley University of Massachusetts Amherst
Taekjip Ha
Taekjip Ha Johns Hopkins University
Sigurd Lenzen
Sigurd Lenzen Hannover Medical School

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