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Biology and Biochemistry

D-Index
112
Citations
49721
World Ranking
891
National Ranking
556

Research.com Recognitions

  • 2003 - Fellow of Alfred P. Sloan Foundation

Overview

Taekjip Ha is affiliated with Johns Hopkins University in the United States. Their research primarily falls within the broad field of Biochemistry, Genetics and Molecular Biology, with a specific focus on Molecular Biology, Cell Biology, Biophysics, Genetics, and Ecology.

Their work covers several main topics, including:

  • RNA and protein synthesis mechanisms
  • Genomics and Chromatin Dynamics
  • CRISPR and Genetic Engineering
  • Advanced biosensing and bioanalysis techniques
  • DNA Repair Mechanisms
  • DNA and Nucleic Acid Chemistry
  • RNA Interference and Gene Delivery

Taekjip Ha has contributed multiple papers to well-known venues throughout their career. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Nature Communications
  • Molecular Cell
  • Nucleic Acids Research

Some recent papers from their work include:

  • "FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices," 2021, eLife
  • "Very fast CRISPR on demand," 2020, Science
  • "Mechanical stress determines the configuration of TGFβ activation in articular cartilage," 2021, Nature Communications
  • "Measuring DNA mechanics on the genome scale," 2020, Nature
  • "Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins," 2023, Nature Methods

Taekjip Ha has collaborated extensively, with frequent co-authors including:

  • Roger S. Zou
  • Sua Myong
  • Momčilo Gavrilov
  • Jaba Mitra
  • Alberto Marín-González

In 2003, Taekjip Ha was awarded the title of Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • A practical guide to single-molecule FRET

    Rahul Roy;Sungchul Hohng;Taekjip Ha;Taekjip Ha

  • Myosin V Walks Hand-Over-Hand: Single Fluorophore Imaging with 1.5-nm Localization

    Ahmet Yildiz;Joseph N. Forkey;Sean A. McKinney;Taekjip Ha;Taekjip Ha

  • Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

    Carsten Grashoff;Brenton D. Hoffman;Michael D. Brenner;Ruobo Zhou

  • A single-molecule study of RNA catalysis and folding.

    Xiaowei Zhuang;Laura E. Bartley;Hazen P. Babcock;Rick Russell

  • Advances in Single-Molecule Fluorescence Methods for Molecular Biology

    Chirlmin Joo;Hamza Balci;Yuji Ishitsuka;Chittanon Buranachai

  • Nonblinking and long-lasting single-molecule fluorescence imaging

    Ivan Rasnik;Sean A McKinney;Taekjip Ha;Taekjip Ha

  • Analysis of Single-Molecule FRET Trajectories Using Hidden Markov Modeling

    Sean A. McKinney;Chirlmin Joo;Taekjip Ha

  • Photophysics of Fluorescent Probes for Single-Molecule Biophysics and Super-Resolution Imaging

    Taekjip Ha;Philip Tinnefeld

  • Probing Single-Stranded DNA Conformational Flexibility Using Fluorescence Spectroscopy

    M.C. Murphy;Ivan Rasnik;Wei Cheng;Timothy M. Lohman

  • Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism

    Taekjip Ha;Alice Y. Ting;Joy Liang;W. Brett Caldwell

  • Single-pair fluorescence resonance energy transfer on freely diffusing molecules: Observation of Förster distance dependence and subpopulations

    Ashok A. Deniz;Maxime Dahan;Jocelyn R. Grunwell;Taekjip Ha;Taekjip Ha

  • Near-complete suppression of quantum dot blinking in ambient conditions.

    Sungchul Hohng;Taekjip Ha

  • Initiation and re-initiation of DNA unwinding by the Escherichia coli Rep helicase

    Taekjip Ha;Ivan Rasnik;Wei Cheng;Hazen P. Babcock

  • Defining single molecular forces required to activate integrin and notch signaling.

    Xuefeng Wang;Taekjip Ha;Taekjip Ha

  • Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study

    Björn Hellenkamp;Björn Hellenkamp;Sonja Schmid;Sonja Schmid;Olga Doroshenko;Oleg Opanasyuk

  • Probing cellular protein complexes using single-molecule pull-down

    Ankur Jain;Ruijie Liu;Biswarathan Ramani;Edwin Arauz

  • Cytosolic Viral Sensor RIG-I Is a 5′-Triphosphate-Dependent Translocase on Double-Stranded RNA

    Su-A Myong;Sheng Cui;Peter V. Cornish;Peter V. Cornish;Axel Kirchhofer

  • Spontaneous intersubunit rotation in single ribosomes.

    Peter V. Cornish;Dmitri N. Ermolenko;Harry F. Noller;Taekjip Ha;Taekjip Ha

  • Structural dynamics of individual Holliday junctions.

    Sean A. McKinney;Anne Cécile Déclais;David M.J. Lilley;Taekjip Ha

  • Single-molecule techniques

    Paul R. Selvin;Taekjip. Ha

Frequent Co-Authors

Sua Myong
Sua Myong Johns Hopkins University
Timothy M. Lohman
Timothy M. Lohman Washington University in St. Louis
Shimon Weiss
Shimon Weiss University of California, Los Angeles
David M.J. Lilley
David M.J. Lilley University of Dundee
Zaida Luthey-Schulten
Zaida Luthey-Schulten University of Illinois at Urbana-Champaign
Yeon-Kyun Shin
Yeon-Kyun Shin Iowa State University
Smita S. Patel
Smita S. Patel Rutgers, The State University of New Jersey
Sarah A. Woodson
Sarah A. Woodson Johns Hopkins University
Edward A. Lemke
Edward A. Lemke Johannes Gutenberg University of Mainz
Kannanganattu V. Prasanth
Kannanganattu V. Prasanth University of Illinois at Urbana-Champaign

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