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Overview

Philip Tinnefeld is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Engineering, with a notable focus on Molecular Biology and Biomedical Engineering. Their work also includes contributions to Biophysics, Electrical and Electronic Engineering, and Materials Chemistry.

The scientist's research topics cover a range of advanced techniques and subjects, including:

  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • Advanced Fluorescence Microscopy Techniques
  • Plasmonic and Surface Plasmon Research
  • Molecular Junctions and Nanostructures
  • DNA and Nucleic Acid Chemistry
  • Biosensors and Analytical Detection

Philip Tinnefeld has published extensively, with frequent appearances in publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • ACS Nano
  • Advanced Materials
  • Angewandte Chemie International Edition

Regarding collaborations, the scientist has worked repeatedly with co-authors:

  • Viktorija Glembockyte
  • Tim Schröder
  • Lennart Grabenhorst
  • Michael Scheckenbach
  • Andrés Manuel Vera

Recent papers authored or co-authored by Philip Tinnefeld include:

  • Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins, 2023, Nature Methods
  • Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope, 2021, Nature Communications
  • Pulsed Interleaved MINFLUX, 2020, Nano Letters
  • Impact of Cyanine Conformational Restraint in the Near-Infrared Range, 2020, The Journal of Organic Chemistry
  • High force catch bond mechanism of bacterial adhesion in the human gut, 2020, Nature Communications

Best Publications

  • Subdiffraction-Resolution Fluorescence Imaging with Conventional Fluorescent Probes†

    Mike Heilemann;Sebastian van de Linde;Mark Schüttpelz;Robert Kasper

  • Single-molecule kinetics and super-resolution microscopy by fluorescence imaging of transient binding on DNA origami.

    Ralf Jungmann;Ralf Jungmann;Christian Steinhauer;Max Scheible;Anton Kuzyk

  • Photophysics of Fluorescent Probes for Single-Molecule Biophysics and Super-Resolution Imaging

    Taekjip Ha;Philip Tinnefeld

  • Fluorescence enhancement at docking sites of DNA-directed self-assembled nanoantennas.

    G. P. Acuna;F. M. Möller;P. Holzmeister;S. Beater

  • A Reducing and Oxidizing System Minimizes Photobleaching and Blinking of Fluorescent Dyes

    Jan Vogelsang;Robert Kasper;Christian Steinhauer;Britta Person

  • Carbocyanine dyes as efficient reversible single-molecule optical switch

    Mike Heilemann;Emmanuel Margeat;Robert Kasper;Markus Sauer

  • Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study

    Björn Hellenkamp;Björn Hellenkamp;Sonja Schmid;Sonja Schmid;Olga Doroshenko;Oleg Opanasyuk

  • On the mechanism of Trolox as antiblinking and antibleaching reagent.

    Thorben Cordes;Jan Vogelsang;Philip Tinnefeld

  • Distance dependence of single-fluorophore quenching by gold nanoparticles studied on DNA origami.

    Guillermo P. Acuna;Martina Bucher;Ingo H. Stein;Christian Steinhauer

  • Controlling the fluorescence of ordinary oxazine dyes for single-molecule switching and superresolution microscopy

    Jan Vogelsang;Thorben Cordes;Carsten Forthmann;Christian Steinhauer

  • Branching Out of Single‐Molecule Fluorescence Spectroscopy: Challenges for Chemistry and Influence on Biology

    Philip Tinnefeld;Markus Sauer

  • The 2015 super-resolution microscopy roadmap

    Stefan W. Hell;Stefan W. Hell;Steffen J. Sahl;Mark Bates;Xiaowei Zhuang

  • Single-Molecule Four-Color FRET Visualizes Energy-Transfer Paths on DNA Origami

    Ingo H. Stein;Christian Steinhauer;Philip Tinnefeld

  • The 2015 super-resolution microscopy roadmap

    Stefan Hell;Steffen Sahl;Mark Bates;Xiaowei Zhuang

  • Molecular force spectroscopy with a DNA origami–based nanoscopic force clamp

    Philipp C. Nickels;Bettina Wünsch;Phil Holzmeister;Wooli Bae

  • DNA Origami as a Nanoscopic Ruler for Super‐Resolution Microscopy

    Christian Steinhauer;Ralf Jungmann;Thomas L. Sobey;Friedrich C. Simmel

  • DNA Origami Nanoantennas with over 5000-fold Fluorescence Enhancement and Single-Molecule Detection at 25 μM.

    Anastasiya Puchkova;Carolin Vietz;Enrico Pibiri;Bettina Wünsch

  • Breaking the concentration limit of optical single-molecule detection

    Phil Holzmeister;Guillermo P. Acuna;Dina Grohmann;Philip Tinnefeld

  • Superresolution microscopy on the basis of engineered dark states.

    Christian Steinhauer;Carsten Forthmann;Jan Vogelsang;Philip Tinnefeld

  • Make them Blink: Probes for Super-Resolution Microscopy

    Jan Vogelsang;Christian Steinhauer;Carsten Forthmann;Ingo H. Stein

  • Multistep Energy Transfer in Single Molecular Photonic Wires

    Mike Heilemann;Philip Tinnefeld;Gabriel Sanchez Mosteiro;Maria Garcia Parajo

Frequent Co-Authors

Markus Sauer
Markus Sauer University of Würzburg
Mike Heilemann
Mike Heilemann Goethe University Frankfurt
Tim Liedl
Tim Liedl Ludwig-Maximilians-Universität München
Stefan W. Hell
Stefan W. Hell Max Planck Society
Aydogan Ozcan
Aydogan Ozcan University of California, Los Angeles
Edward A. Lemke
Edward A. Lemke Johannes Gutenberg University of Mainz
Zhike He
Zhike He Wuhan University
Don C. Lamb
Don C. Lamb Ludwig-Maximilians-Universität München
Friedrich C. Simmel
Friedrich C. Simmel Technical University of Munich
Taekjip Ha
Taekjip Ha Johns Hopkins University

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