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Chemistry

D-Index
61
Citations
16120
World Ranking
9138
National Ranking
654

Overview

Mike Heilemann is affiliated with Goethe University Frankfurt in Germany and has a significant publication record in the field of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields, including Biophysics, Molecular Biology, Structural Biology, Cellular and Molecular Neuroscience, and Radiology, Nuclear Medicine, and Imaging.

The scientist's research frequently appears in prominent publication venues such as Zenodo (CERN European Organization for Nuclear Research), bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Biophysical Journal, and Angewandte Chemie International Edition.

Mike Heilemann's main topics of research include:

  • Advanced Fluorescence Microscopy Techniques
  • Cell Image Analysis Techniques
  • Advanced Electron Microscopy Techniques and Applications
  • Monoclonal and Polyclonal Antibodies Research
  • Advanced Biosensing Techniques and Applications
  • Neural dynamics and brain function
  • Image Processing Techniques and Applications

Their research output includes notable papers such as:

  • "Democratising deep learning for microscopy with ZeroCostDL4Mic" (2021), published in Nature Communications
  • "Universal quenching of common fluorescent probes by water and alcohols" (2020), published in Chemical Science
  • "Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum" (2023), published in Nature
  • "Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors" (2020), published in Nature Chemical Biology
  • "Exchangeable HaloTag Ligands for Super-Resolution Fluorescence Microscopy" (2023), published in Journal of the American Chemical Society

Mike Heilemann has collaborated extensively with other researchers, with frequent coauthors including Christoph Spahn, Marina S. Dietz, Marius Glogger, Christos Karathanasis, and Johanna V. Rahm. The number of joint publications with these colleagues ranges from 20 to over 30, indicating sustained collaborative efforts within their research network.

Best Publications

  • Subdiffraction-Resolution Fluorescence Imaging with Conventional Fluorescent Probes†

    Mike Heilemann;Sebastian van de Linde;Mark Schüttpelz;Robert Kasper

  • A Reducing and Oxidizing System Minimizes Photobleaching and Blinking of Fluorescent Dyes

    Jan Vogelsang;Robert Kasper;Christian Steinhauer;Britta Person

  • Carbocyanine dyes as efficient reversible single-molecule optical switch

    Mike Heilemann;Emmanuel Margeat;Robert Kasper;Markus Sauer

  • Super-resolution imaging with small organic fluorophores.

    Mike Heilemann;Sebastian van de Linde;Anindita Mukherjee;Markits Sauer

  • Reconfigurable, braced, three- dimensional DNA nanostructures

    Russell P. Goodman;Mike Heilemann;Sören Doose;Christoph M. Erben

  • Single-Molecule Localization Microscopy in Eukaryotes.

    Markus Sauer;Mike Heilemann

  • Live-cell super-resolution imaging with trimethoprim conjugates

    Richard Wombacher;Meike Heidbreder;Sebastian van de Linde;Michael P Sheetz

  • Live-Cell Super-Resolution Imaging with Synthetic Fluorophores

    Sebastian van de Linde;Mike Heilemann;Markus Sauer

  • Photoswitches: Key molecules for subdiffraction-resolution fluorescence imaging and molecular quantification

    Mike Heilemann;Peter Dedecker;Johan Hofkens;Markus Sauer

  • Universal quenching of common fluorescent probes by water and alcohols

    Jimmy Maillard;Kathrin Klehs;Christopher Rumble;Eric Vauthey

  • A simple method to estimate the average localization precision of a single-molecule localization microscopy experiment

    Ulrike Endesfelder;Sebastian Malkusch;Franziska Fricke;Mike Heilemann

  • Photoinduced formation of reversible dye radicals and their impact on super-resolution imaging

    Sebastian van de Linde;Ivan Krstić;Thomas Prisner;Sören Doose

  • Multistep Energy Transfer in Single Molecular Photonic Wires

    Mike Heilemann;Philip Tinnefeld;Gabriel Sanchez Mosteiro;Maria Garcia Parajo

  • Coordinate-based colocalization analysis of single-molecule localization microscopy data

    Sebastian Malkusch;Ulrike Endesfelder;Justine Mondry;Márton Gelléri

  • Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation

    Sjoerd J. L. van Wijk;Franziska Fricke;Lina Herhaus;Jalaj Gupta

  • Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum

    Unknown

  • The effect of photoswitching kinetics and labeling densities on super-resolution fluorescence imaging

    Sebastian van de Linde;Steve Wolter;Mike Heilemann;Markus Sauer

  • Fluorescence microscopy beyond the diffraction limit.

    Mike Heilemann

  • Super-resolution fluorescence imaging of chromosomal DNA.

    Patrick J.M. Zessin;Kieran Finan;Mike Heilemann

  • Whole-Cell, 3D, and Multicolor STED Imaging with Exchangeable Fluorophores.

    Christoph Spahn;Jonathan B. Grimm;Luke D. Lavis;Marko Lampe

  • Super-resolution Imaging Reveals the Internal Architecture of Nano-sized Syntaxin Clusters

    Dana Bar-On;Steve Wolter;Sebastian van de Linde;Mike Heilemann

  • Subdiffraction-resolution fluorescence imaging of proteins in the mitochondrial inner membrane with photoswitchable fluorophores.

    Sebastian van de Linde;Markus Sauer;Mike Heilemann

Frequent Co-Authors

Markus Sauer
Markus Sauer University of Würzburg
Philip Tinnefeld
Philip Tinnefeld Ludwig-Maximilians-Universität München
Robert Tampé
Robert Tampé Goethe University Frankfurt
Christian Kaltschmidt
Christian Kaltschmidt Bielefeld University
Ralf Jungmann
Ralf Jungmann Max Planck Society
Jean-Baptiste Sibarita
Jean-Baptiste Sibarita Centre national de la recherche scientifique, CNRS
Gerhard Hummer
Gerhard Hummer Max Planck Society
Daniel Choquet
Daniel Choquet University of Bordeaux
Erin M. Schuman
Erin M. Schuman Max Planck Society
Shimon Weiss
Shimon Weiss University of California, Los Angeles

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