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D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
15523
World Ranking
11231
National Ranking
802

Overview

Edward A. Lemke is affiliated with Johannes Gutenberg University of Mainz in Germany. Their research primarily contributes to the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology as the main subfield. Other notable subfields of study include Biophysics, Cell Biology, Materials Chemistry, and Organic Chemistry.

The scientist's work covers various topics, reflecting a broad interest in molecular and cellular mechanisms. Key topics include RNA Research and Splicing, RNA and protein synthesis mechanisms, Nuclear Structure and Function, Protein Structure and Dynamics, RNA modifications and cancer, Heat shock proteins research, and Click Chemistry and Applications.

Edward A. Lemke's recent publications span a range of journals and subjects. Selected papers include:

  • "FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices," published in 2021 in eLife
  • "PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins," published in 2020 in Nucleic Acids Research
  • "Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins," published in 2023 in Nature Methods
  • "Visualizing the disordered nuclear transport machinery in situ," published in 2023 in Nature
  • "Bio-orthogonal Red and Far-Red Fluorogenic Probes for Wash-Free Live-Cell and Super-resolution Microscopy," published in 2021 in ACS Central Science

Frequent publication venues for their work include Biophysical Journal, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Journal of Molecular Biology, and eLife.

Collaboration plays a significant role in their research, with frequent co-authors being Miao Yu, Christopher D. Reinkemeier, Tom Scheidt, Christine Koehler, and Anders Barth.

Best Publications

  • Molecular Anatomy of a Trafficking Organelle

    Shigeo Takamori;Matthew Holt;Katinka Stenius;Edward A. Lemke

  • A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins.

    Gražvydas Lukinavičius;Keitaro Umezawa;Nicolas Olivier;Alf Honigmann

  • Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study

    Björn Hellenkamp;Björn Hellenkamp;Sonja Schmid;Sonja Schmid;Olga Doroshenko;Oleg Opanasyuk

  • In situ structural analysis of the human nuclear pore complex

    Alexander von Appen;Jan Kosinski;Lenore Sparks;Alessandro Ori

  • Single-molecule biophysics: at the interface of biology, physics and chemistry

    Ashok A Deniz;Samrat Mukhopadhyay;Edward A Lemke

  • Fourier ring correlation as a resolution criterion for super-resolution microscopy.

    Niccolò Banterle;Khanh Huy Bui;Edward A. Lemke;Martin Beck

  • Amino Acids for Diels–Alder Reactions in Living Cells

    Tilman Plass;Sigrid Milles;Christine Koehler;Jędrzej Szymański

  • A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures

    Samrat Mukhopadhyay;Rajaraman Krishnan;Edward A. Lemke;Susan Lindquist

  • Genetically encoded copper-free click chemistry.

    Tilman Plass;Sigrid Milles;Christine Koehler;Carsten Schultz

  • Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines

    Alessandro Ori;Niccolò Banterle;Murat Iskar;Amparo Andrés-Pons

  • Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors

    Sigrid Milles;Davide Mercadante;Iker Valle Aramburu;Malene Ringkjøbing Jensen;Malene Ringkjøbing Jensen

  • Minimal Tags for Rapid Dual‐Color Live‐Cell Labeling and Super‐Resolution Microscopy

    Ivana Nikić;Tilman Plass;Oliver Schraidt;Jędrzej Szymański

  • FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

    Eitan Lerner;Anders Barth;Jelle Hendrix;Benjamin Ambrose

  • Control of protein phosphorylation with a genetically encoded photocaged amino acid

    Edward A Lemke;Daniel Summerer;Bernhard H Geierstanger;Scott M Brittain

  • Genetic Incorporation of a Small, Environmentally Sensitive, Fluorescent Probe into Proteins in Saccharomyces cerevisiae

    Hyun Soo Lee;Jiantao Guo;Edward A. Lemke;Romerson D. Dimla

  • A General and Efficient Method for the Site-Specific Dual-Labeling of Proteins for Single Molecule Fluorescence Resonance Energy Transfer

    Eric M. Brustad;Edward A. Lemke;Peter G. Schultz;Ashok A. Deniz

  • Decoupling of size and shape fluctuations in heteropolymeric sequences reconciles discrepancies in SAXS vs. FRET measurements

    Gustavo Fuertes;Niccolò Banterle;Kiersten M Ruff;Aritra Chowdhury

  • Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET

    Maolin Lu;Xiaochu Ma;Luis R. Castillo-Menendez;Jason Gorman

  • Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation

    Annika Borrmann;Sigrid Milles;Tilman Plass;Jan Dommerholt

  • Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes

    Christopher D. Reinkemeier;Gemma Estrada Girona;Edward A. Lemke

Frequent Co-Authors

Carsten Schultz
Carsten Schultz Oregon Health & Science University
Dmitri I. Svergun
Dmitri I. Svergun European Bioinformatics Institute
Martin Blackledge
Martin Blackledge Grenoble Alpes University
Imre Berger
Imre Berger University of Bristol
Don C. Lamb
Don C. Lamb Ludwig-Maximilians-Universität München
Martin Beck
Martin Beck TU Dresden
Juri Rappsilber
Juri Rappsilber Technical University of Berlin
Philip Tinnefeld
Philip Tinnefeld Ludwig-Maximilians-Universität München
Taekjip Ha
Taekjip Ha Johns Hopkins University
Peter G. Schultz
Peter G. Schultz Scripps Research Institute

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