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Matthew John Smalley

Matthew John Smalley

D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
9814
World Ranking
19227
National Ranking
1490

Overview

Matthew John Smalley is affiliated with Cardiff University in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with an emphasis on Medicine. Within these areas, Smalley has contributed extensively to Molecular Biology, Oncology, Genetics, Pulmonary and Respiratory Medicine, and Cell Biology.

The main topics addressed in their work include:

  • Cancer Cells and Metastasis
  • Veterinary Oncology Research
  • Virus-based gene therapy research
  • Wnt/β-catenin signaling in development and cancer
  • Hippo pathway signaling and YAP/TAZ
  • Infectious Diseases and Mycology
  • DNA Repair Mechanisms

Smalley has published in several frequent venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Canine Medicine and Genetics
  • Disease Models & Mechanisms
  • Cancers
  • International Journal of Molecular Sciences

The scientist's recent papers include:

  • The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling (2020, International Journal of Molecular Sciences)
  • Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study (2021, Canine Medicine and Genetics)
  • Immune Remodeling of the Extracellular Matrix Drives Loss of Cancer Stem Cells and Tumor Rejection (2020, Cancer Immunology Research)
  • Associations Between Dog Breed and Clinical Features of Mammary Epithelial Neoplasia in Bitches: an Epidemiological Study of Submissions to a Single Diagnostic Pathology Centre Between 2008-2021 (2023, Journal of Mammary Gland Biology and Neoplasia)
  • Dog breeds and conformations predisposed to osteosarcoma in the UK: a VetCompass study (2023, Canine Medicine and Genetics)

Frequent collaborators in Smalley's research include Howard Kendrick, Giusy Tornillo, Sam Beck, Trevor Hay, and Dan G. O'Neill.

Best Publications

  • BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

    Gemma Molyneux;Felipe C. Geyer;Fiona-Ann Magnay;Afshan McCarthy

  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

    Suzanne A. Eccles;Eric O. Aboagye;Simak Ali;Annie S. Anderson

  • Stem cells and breast cancer: A field in transit.

    Matthew John Smalley;Alan Ashworth

  • The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling.

    Boris Y. Shorning;Manisha S. Dass;Matthew J. Smalley;Helen B. Pearson

  • CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells

    Katherine E. Sleeman;Howard Kendrick;Alan Ashworth;Clare M. Isacke

  • Functional and molecular characterisation of mammary side population cells

    Azra J. Alvi;Helen Clayton;Chirag Joshi;Tariq Enver

  • Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland.

    Katherine E. Sleeman;Howard Kendrick;David Robertson;Clare M. Isacke

  • Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

    Matthew J. Smalley;Elizabeth Sara;Hugh Paterson;Stuart Naylor

  • Wnt signalling in mammalian development and cancer

    Matthew John Smalley;Trevor Clive Dale

  • A divergent canonical WNT-signaling pathway regulates microtubule dynamics: Dishevelled signals locally to stabilize microtubules

    Lorenza Ciani;Olga Y. Krylova;Matthew J. Smalley;Trevor C Dale

  • Alpha‐6 integrin is necessary for the tumourigenicity of a stem cell‐like subpopulation within the MCF7 breast cancer cell line

    Massimiliano Cariati;Ali Naderi;John P. Brown;Matthew John Smalley

  • Pregnancy and the risk of breast cancer.

    Kara Louise Britt;Alan Ashworth;Matthew J Smalley

  • Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate

    Howard Kendrick;Joseph Regan;Fiona-Ann Magnay;Anita Grigoriadis

  • Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding.

    Marie-Therese Webster;Magdalena Rozycka;Elizabeth Sara;Elaine Davis

  • Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development

    Lena Sarkar;Martyn Cobourne;Stuart Naylor;Matthew Smalley

  • Correction: Functional and molecular characterisation of mammary side population cells

    Azra J Alvi;Helen Clayton;Chirag Joshi;Tariq Enver

  • PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression

    Kelly Chiang;Agnieszka E. Zielinska;Abeer M. Shaaban;Maria Pilar Sanchez-Bailon

  • The Mammary gland "Side Population": A putative stem/progenitor cell marker?

    Matthew John Smalley;Robert B. Clarke

  • Identification of the Axin and Frat Binding Region of Glycogen Synthase Kinase-3

    Elizabeth Fraser;Neville Young;Rana Dajani;Jonathan Franca-Koh

  • Functional and molecular characterisation of mammary side population cells (vol 5, pg R1, 2003)

    A. J Alvi;H Clayton;C Joshi;T Enver

Frequent Co-Authors

Trevor Clive Dale
Trevor Clive Dale Cardiff University
Alan Ashworth
Alan Ashworth University of California, San Francisco
Andrew Tutt
Andrew Tutt Institute of Cancer Research
Jorge S. Reis-Filho
Jorge S. Reis-Filho Memorial Sloan Kettering Cancer Center
Alan Mackay
Alan Mackay Institute of Cancer Research
Clare M. Isacke
Clare M. Isacke Institute of Cancer Research
Jane E. Visvader
Jane E. Visvader Walter and Eliza Hall Institute of Medical Research
Geoffrey J. Lindeman
Geoffrey J. Lindeman Peter MacCallum Cancer Centre
Marketa Zvelebil
Marketa Zvelebil University of Basel
Alan Richard Clarke
Alan Richard Clarke Cardiff University

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