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Biology and Biochemistry

D-Index
49
Citations
18006
World Ranking
17824
National Ranking
7295

Overview

Roberto D. Polakiewicz is affiliated with Cell Signaling Technology in the United States. Their research primarily focuses on areas within Biochemistry, Genetics, and Molecular Biology, with particular attention to Molecular Biology and Cell Biology. In addition, their work touches on Infectious Diseases and Health, reflecting a multidisciplinary approach across biological and medical sciences.

Their main topics of study include:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Vaccine Coverage and Hesitancy
  • 14-3-3 Protein Interactions
  • Ubiquitin and Proteasome Pathways
  • Microtubule and Mitosis Dynamics
  • Hippo Pathway Signaling and YAP/TAZ

Roberto D. Polakiewicz has contributed to several scientific publications spanning from 2020 to 2024. Notable papers include:

  • "Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19" (2022, Virulence)
  • "MAPKAP Kinase-2 phosphorylation of PABPC1 controls its interaction with 14-3-3 proteins after DNA damage: A combined kinase and protein array approach" (2023, Frontiers in Molecular Biosciences)
  • "InTraSeq: A Multimodal Assay that Uncovers New Single-Cell Biology and Regulatory Mechanisms" (2024, bioRxiv [Cold Spring Harbor Laboratory])
  • "YAP vs. TAZ: differences in expression revealed through rigorous validation of target-specific monoclonal antibodies" (2020, Journal of Histotechnology)

Their work has been published in various venues including:

  • Virulence
  • Frontiers in Molecular Biosciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Histotechnology

Polakiewicz frequently collaborates with other researchers. Some frequent coauthors include:

  • David J. Gregory
  • Augustin Vannier
  • Akiro H. Duey
  • Tyler J. Roady
  • Richard K. Dzeng

Best Publications

  • Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer

    Klarisa Rikova;Ailan Guo;Qingfu Zeng;Anthony Possemato

  • Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

    Anne-Claude Gingras;Steven P. Gygi;Brian Raught;Roberto D. Polakiewicz

  • Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

    John Rush;Albrecht Moritz;Kimberly A. Lee;Ailan Guo

  • Hierarchical phosphorylation of the translation inhibitor 4E-BP1

    Anne-Claude Gingras;Brian Raught;Steven P. Gygi;Steven P. Gygi;Anna Niedzwiecka

  • Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth

    Taro Hitosugi;Sumin Kang;Matthew G. Vander Heiden;Tae Wook Chung

  • Signaling networks assembled by oncogenic EGFR and c-Met

    Ailan Guo;Judit Villén;Jon Kornhauser;Kimberly A. Lee

  • Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

    Brian Raught;Franck Peiretti;Anne-Claude Gingras;Mark Livingstone

  • Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance.

    Frédéric Tremblay;Sophie Brûlé;Sung Hee Um;Yu Li

  • Protein Kinase C θ Inhibits Insulin Signaling by Phosphorylating IRS1 at Ser1101

    Yu Li;Timothy J. Soos;Xinghai Li;Jiong Wu

  • Diagnosis of NUT midline carcinoma using a NUT-specific monoclonal antibody.

    Herbert Haack;Laura A. Johnson;Christopher J. Fry;Katherine Crosby

  • Profiling of UV-induced ATM/ATR signaling pathways

    Matthew P. Stokes;John Rush;Joan MacNeill;Jian Min Ren

  • Activating alleles of JAK3 in acute megakaryoblastic leukemia

    Denise K. Walters;Denise K. Walters;Thomas Mercher;Ting Lei Gu;Thomas O'Hare;Thomas O'Hare

  • Tyrosine Phosphorylation of Mitochondrial Pyruvate Dehydrogenase Kinase 1 Is Important for Cancer Metabolism

    Taro Hitosugi;Jun Fan;Tae Wook Chung;Katherine Lythgoe

  • Phosphoprotein Analysis Using Antibodies Broadly Reactive against Phosphorylated Motifs

    Hui Zhang;Xiangming Zha;Yi Tan;Peter V. Hornbeck

  • Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer.

    Jian Yu;Susan Kane;Jiong Wu;Elisa Benedettini

  • mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control.

    Roberto D. Polakiewicz;Sandra M. Schieferl;Anne-Claude Gingras;Nahum Sonenberg

  • Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD+ Redox Homeostasis in Cancer Cells

    Jun Fan;Taro Hitosugi;Tae Wook Chung;Jianxin Xie

  • Expression of the AID protein in normal and neoplastic B cells.

    Laura Pasqualucci;Roberta Guglielmino;Jane Houldsworth;Jessica Mohr

  • Kinase Domain Mutants of Bcr-Abl Exhibit Altered Transformation Potency, Kinase Activity, and Substrate Utilization, Irrespective of Sensitivity to Imatinib‡

    Ian J. Griswold;Mary MacPartlin;Thomas Bumm;Valerie L. Goss

  • Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T

    Xiaodong Zhang;Ailan Guo;Jianshi Yu;Anthony Possemato

Frequent Co-Authors

Michael J. Comb
Michael J. Comb Cell Signaling Technology (United States)
Steven P. Gygi
Steven P. Gygi Harvard University
Sagar Lonial
Sagar Lonial Emory University
Brian J. Druker
Brian J. Druker Oregon Health & Science University
Titus J. Boggon
Titus J. Boggon Yale University
Fadlo R. Khuri
Fadlo R. Khuri American University of Beirut
Michael Heinrich
Michael Heinrich Oregon Health & Science University
Nahum Sonenberg
Nahum Sonenberg McGill University
D. Gary Gilliland
D. Gary Gilliland Fred Hutchinson Cancer Research Center
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute

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