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D-Index & Metrics

Biology and Biochemistry

D-Index
102
Citations
42603
World Ranking
1349
National Ranking
784

Overview

Scot R. Kimball is affiliated with Pennsylvania State University in the United States. Their research spans multiple disciplines, focusing primarily on biochemistry, genetics, and molecular biology, with additional significant contributions to medicine. Their work encompasses key subfields such as molecular biology, cell biology, epidemiology, nephrology, and cancer research.

Their scientific inquiries have centered on several main topics, including:

  • Muscle Physiology and Disorders
  • Liver Disease Diagnosis and Treatment
  • Endoplasmic Reticulum Stress and Disease
  • Protein Kinase Regulation and GTPase Signaling
  • PI3K/AKT/mTOR signaling in cancer
  • Muscle metabolism and nutrition
  • Epigenetics and DNA Methylation

Among recent publications, key papers include:

  • "AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology," Journal of Cachexia Sarcopenia and Muscle, 2021
  • "NASHFit: A randomized controlled trial of an exercise training program to reduce clotting risk in patients with NASH," Hepatology, 2021
  • "Exercise Attenuates Ribosomal Protein Six Phosphorylation in Fatty Liver Disease," Digestive Diseases and Sciences, 2020
  • "Salubrinal in Combination With 4E1RCat Synergistically Impairs Melanoma Development by Disrupting the Protein Synthetic Machinery," Frontiers in Oncology, 2020
  • "PERK/ATF4-dependent expression of the stress response protein REDD1 promotes proinflammatory cytokine expression in the heart of obese mice," American Journal of Physiology-Endocrinology and Metabolism, 2022

Frequent collaborators in their research include Michael D. Dennis, Siddharth Sunilkumar, Allyson L. Toro, Ashley M. VanCleave, and Paul A. Roberson. These collaborations reinforce multi-disciplinary approaches and extend to various facets of cellular and physiological regulation.

Scot R. Kimball has published extensively in prominent research venues. Notable journals featuring their work are:

  • Journal of Biological Chemistry
  • Journal of Applied Physiology
  • American Journal of Physiology-Endocrinology and Metabolism
  • Diabetes
  • The FASEB Journal

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling.

    Douglas R. Bolster;Stephen J. Crozier;Scot R. Kimball;Leonard S. Jefferson

  • Leucine Stimulates Translation Initiation in Skeletal Muscle of Postabsorptive Rats via a Rapamycin-Sensitive Pathway

    Joshua C. Anthony;Fumiaki Yoshizawa;Tracy Gautsch Anthony;Thomas C. Vary

  • Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.

    David A. Antonetti;Alistair J. Barber;Sarah K. Bronson;Willard M. Freeman

  • Signaling Pathways and Molecular Mechanisms through which Branched-Chain Amino Acids Mediate Translational Control of Protein Synthesis

    Scot R. Kimball;Leonard S. Jefferson

  • Signaling Pathways Involved in Translational Control of Protein Synthesis in Skeletal Muscle by Leucine

    Joshua C. Anthony;Tracy G. Anthony;Scot R. Kimball;Leonard S. Jefferson

  • Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo.

    Andrew Jan Waskiewicz;Jeffrey C. Johnson;Bennett Penn;Bennett Penn;Malathy Mahalingam

  • Orally Administered Leucine Stimulates Protein Synthesis in Skeletal Muscle of Postabsorptive Rats in Association with Increased eIF4F Formation

    Joshua C. Anthony;Tracy Gautsch Anthony;Scot R. Kimball;Thomas C. Vary

  • The GCN2 eIF2α Kinase Is Required for Adaptation to Amino Acid Deprivation in Mice

    Peichuan Zhang;Peichuan Zhang;Barbara C. McGrath;Jamie Reinert;De Anne S. Olsen

  • Oral Leucine Administration Stimulates Protein Synthesis in Rat Skeletal Muscle

    Stephen J. Crozier;Scot R. Kimball;Sans W. Emmert;Joshua C. Anthony

  • Eukaryotic initiation factor eIF2

    Scot R Kimball

  • Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.

    Scot R. Kimball;Lisa M. Shantz;Rick L. Horetsky;Leonard S. Jefferson

  • Dexamethasone Represses Signaling through the Mammalian Target of Rapamycin in Muscle Cells by Enhancing Expression of REDD1

    Hongmei Wang;Neil Kubica;Leif W. Ellisen;Leonard S. Jefferson

  • Invited Review: Role of insulin in translational control of protein synthesis in skeletal muscle by amino acids or exercise

    Scot R. Kimball;Peter A. Farrell;Leonard S. Jefferson

  • Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes.

    Scot R. Kimball;Rick L. Horetsky;David Ron;Leonard S. Jefferson

  • 4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle.

    O. Jameel Shah;Joshua C. Anthony;Scot R. Kimball;Leonard S. Jefferson

  • eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine–nucleotide exchange

    Graham D. Pavitt;Kolluru V.A. Ramaiah;Kolluru V.A. Ramaiah;Scot R. Kimball;Alan G. Hinnebusch

  • Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle

    Douglas R. Bolster;Neil Kubica;Stephen J. Crozier;David L. Williamson

  • New functions for amino acids: effects on gene transcription and translation

    Scot R Kimball;Leonard S Jefferson

  • Regulation of protein synthesis associated with skeletal muscle hypertrophy by insulin-, amino acid- and exercise-induced signalling.

    Douglas R. Bolster;Leonard S. Jefferson;Scot R. Kimball

Frequent Co-Authors

Leonard S. Jefferson
Leonard S. Jefferson Pennsylvania State University
Charles H. Lang
Charles H. Lang Pennsylvania State University
Douglas R. Cavener
Douglas R. Cavener Pennsylvania State University
Gavin P. Robertson
Gavin P. Robertson Pennsylvania State University
John C. Lawrence
John C. Lawrence University of Virginia
Ronald C. Wek
Ronald C. Wek Indiana University
Patrice Fort
Patrice Fort University of Michigan–Ann Arbor
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Antonis E. Koromilas
Antonis E. Koromilas McGill University
Robert L. Matts
Robert L. Matts Oklahoma State University

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