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Biology and Biochemistry

D-Index
58
Citations
12951
World Ranking
13111
National Ranking
5590

Overview

Gavin P. Robertson is affiliated with Pennsylvania State University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a substantial emphasis on Molecular Biology, Oncology, Immunology, Physiology, and Cancer Research.

The scientist's work focuses on several main topics, including:

  • Telomeres, Telomerase, and Senescence
  • Extracellular vesicles in disease
  • Multiple Myeloma Research and Treatments
  • CRISPR and Genetic Engineering
  • Cancer Cells and Metastasis
  • Chronic Lymphocytic Leukemia Research
  • PI3K/AKT/mTOR signaling in cancer

Frequent co-authors collaborating with Robertson include:

  • Shantu Amin
  • Krishne Gowda
  • Saketh S. Dinavahi
  • Jiyue Zhu
  • Yu-Chi Chen

Robertson has published articles in several scientific journals. Recurring venues of publication are Pharmacological Research, bioRxiv (Cold Spring Harbor Laboratory), Cancer Treatment Reviews, Frontiers in Oncology, and Proceedings of the National Academy of Sciences.

Selected recent papers authored or co-authored by Robertson include:

  • "The role of exosomes in metastasis and progression of melanoma," 2020, Cancer Treatment Reviews
  • "Salubrinal in Combination With 4E1RCat Synergistically Impairs Melanoma Development by Disrupting the Protein Synthetic Machinery," 2020, Frontiers in Oncology
  • "Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene," 2021, Proceedings of the National Academy of Sciences
  • "Development of a novel Bruton's tyrosine kinase inhibitor that exerts anti-cancer activities potentiates response of chemotherapeutic agents in multiple myeloma stem cell-like cells," 2022, Frontiers in Pharmacology
  • "Pharmacological agents targeting drug-tolerant persister cells in cancer," 2024, Pharmacological Research

Best Publications

  • Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

    Joseph F. Costello;Joseph F. Costello;Michael C. Frühwald;Michael C. Frühwald;Dominic J. Smiraglia;Laura J. Rush

  • Deregulated Akt3 Activity Promotes Development of Malignant Melanoma

    Jill M. Stahl;Arati Sharma;Mitchell Cheung;Melissa Zimmerman

  • Suppression of BRAFV599E in Human Melanoma Abrogates Transformation

    Sunil R. Hingorani;Michael A. Jacobetz;Gavin P. Robertson;Meenhard Herlyn

  • The Role of Cholesterol in Cancer

    Omer F. Kuzu;Mohammad A. Noory;Gavin P. Robertson

  • Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors.

    Arati Sharma;Nishit R. Trivedi;Melissa A. Zimmerman;David A. Tuveson

  • Transiently entrapped circulating tumor cells interact with neutrophils to facilitate lung metastasis development.

    Sung Jin Huh;Shile Liang;Arati Sharma;Cheng Dong

  • Loss of PTEN Promotes Tumor Development in Malignant Melanoma

    Jill M Stahl;Mitchell Cheung;Arati Sharma;Nishit R Trivedi

  • Akt3 and Mutant V600EB-Raf Cooperate to Promote Early Melanoma Development

    Mitchell Cheung;Arati Sharma;Subba Rao V. Madhunapantula;Gavin P. Robertson

  • Targeting the MAPK pathway in melanoma: Why some approaches succeed and other fail

    Gajanan S. Inamdar;Subba Rao V. Madhunapantula;Gavin P. Robertson

  • Functional and therapeutic significance of Akt deregulation in malignant melanoma.

    Gavin P. Robertson

  • Systemic Delivery of Liposomal Short-Chain Ceramide Limits Solid Tumor Growth in Murine Models of Breast Adenocarcinoma

    Thomas C. Stover;Arati Sharma;Gavin P. Robertson;Mark Kester

  • Toxicological considerations when creating nanoparticle-based drugs and drug delivery systems

    Arati Sharma;SubbaRao V Madhunapantula;Gavin P Robertson

  • Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development.

    Melissa A. Tran;Raghavendra Gowda;Arati Sharma;Eun Joo Park

  • Intravenous Delivery of siRNA Targeting CD47 Effectively Inhibits Melanoma Tumor Growth and Lung Metastasis

    Yuhua Wang;Zhenghong Xu;Shutao Guo;Lu Zhang

  • Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development.

    Melissa A. Tran;Charles D. Smith;Mark Kester;Gavin P. Robertson

  • The PTEN-AKT3 Signaling Cascade as a Therapeutic Target in Melanoma

    SubbaRao V. Madhunapantula;Gavin P. Robertson

  • PRAS40 deregulates apoptosis in malignant melanoma.

    Subba Rao V. Madhunapantula;Arati Sharma;Gavin P. Robertson

  • eEF-2 Kinase Dictates Cross-Talk between Autophagy and Apoptosis Induced by Akt Inhibition, Thereby Modulating Cytotoxicity of Novel Akt Inhibitor MK-2206

    Yan Cheng;Xingcong Ren;Yi Zhang;Yi Zhang;Rajesh Patel

  • Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases.

    Arati Sharma;Melissa A. Tran;Shile Liang;Arun K. Sharma

  • Use of liposomes as drug delivery vehicles for treatment of melanoma

    Melissa A. Tran;Rebecca J. Watts;Gavin P. Robertson

Frequent Co-Authors

Shantu Amin
Shantu Amin Pennsylvania State University
Arun K. Sharma
Arun K. Sharma University of Calcutta
Webster K. Cavenee
Webster K. Cavenee University of California, San Diego
Charles D. Smith
Charles D. Smith University of Kentucky
Scot R. Kimball
Scot R. Kimball Pennsylvania State University
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Yiling Lu
Yiling Lu The University of Texas MD Anderson Cancer Center
Jin-Ming Yang
Jin-Ming Yang University of Kentucky
Antonis E. Koromilas
Antonis E. Koromilas McGill University
James H. Adair
James H. Adair Pennsylvania State University

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