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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
41689
World Ranking
3070
National Ranking
65

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Matthias P. Lutolf is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. The scientist's research spans multiple fields with a primary focus on Biochemistry, Genetics and Molecular Biology, supported by a substantial body of work. Medicine is also a significant area of study. Subfields include Molecular Biology, Biomedical Engineering, Oncology, Cell Biology, and Surgery.

The work covers a variety of topics, prominently featuring 3D Printing in Biomedical Research, Cancer Cells and Metastasis, and Pluripotent Stem Cells Research. Other areas of investigation include Single-cell and spatial transcriptomics, Cellular Mechanics and Interactions, Tissue Engineering and Regenerative Medicine, as well as Renal and related cancers.

Matthias P. Lutolf has contributed to a range of peer-reviewed articles published in notable scientific venues. Frequent publication platforms include bioRxiv (Cold Spring Harbor Laboratory) with 22 papers, Nature Communications with 8 publications, Nature Materials with 4, Cell Stem Cell with 4, and Stem Cell Reports with 4.

Recent significant papers authored or co-authored by Matthias P. Lutolf are:

  • Engineering organoids, 2021, Nature Reviews Materials
  • Homeostatic mini-intestines through scaffold-guided organoid morphogenesis, 2020, Nature
  • Tissue geometry drives deterministic organoid patterning, 2022, Science
  • Recapitulating macro-scale tissue self-organization through organoid bioprinting, 2020, Nature Materials
  • Next-generation cancer organoids, 2021, Nature Materials

Collaborations are a key element of their research activity. Frequent co-authors include:

  • Nicolas Broguière
  • Nathalie Brandenberg
  • Tania Hübscher
  • Saba Rezakhani
  • Mikhail Nikolaev

Recognition for academic contributions includes membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

    M P Lutolf;M P Lutolf;J A Hubbell

  • Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: Engineering cell-invasion characteristics

    M. P. Lutolf;J. L. Lauer-Fields;H. G. Schmoekel;H. G. Schmoekel;A. T. Metters

  • Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

    P. M. Gilbert;K. L. Havenstrite;Klas E. G. Magnusson;Klas E. G. Magnusson;A. Sacco

  • Designing materials to direct stem-cell fate

    Matthias P. Lutolf;Penney M. Gilbert;Helen M. Blau

  • Designer matrices for intestinal stem cell and organoid culture

    Nikolce Gjorevski;Norman Sachs;Andrea Manfrin;Sonja Giger

  • NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

    Hongbo Zhang;Dongryeol Ryu;Yibo Wu;Karim Gariani

  • Repair of bone defects using synthetic mimetics of collagenous extracellular matrices.

    Matthias P. Lutolf;Franz E. Weber;Hugo G. Schmoekel;Jason C. Schense

  • Progress and potential in organoid research.

    Giuliana Rossi;Andrea Manfrin;Matthias P. Lutolf

  • Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition.

    M. P. Lutolf;J. A. Hubbell

  • Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells.

    Daniela Loessner;Kathryn S. Stok;Matthias P. Lutolf;Dietmar W. Hutmacher

  • Molecularly Engineered PEG Hydrogels: A Novel Model System for Proteolytically Mediated Cell Migration

    G.P. Raeber;M.P. Lutolf;J.A. Hubbell

  • Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth

    Andreas H. Zisch;Matthias P. Lutolf;Martin Ehrbar;George P. Raeber

  • Cell-responsive synthetic hydrogels

    Matthias P. Lutolf;George P. Raeber;Andreas H. Zisch;Nicola Tirelli

  • Homeostatic mini-intestines through scaffold-guided organoid morphogenesis

    Mikhail Nikolaev;Olga Mitrofanova;Nicolas Broguiere;Sara Geraldo

  • Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

    Marlen Knobloch;Simon M. G. Braun;Simon M. G. Braun;Luis Zurkirchen;Carolin Von Schoultz

  • Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix.

    Mikaël M. Martino;Priscilla S. Briquez;Adrian Ranga;Matthias P. Lutolf

  • Protein delivery from materials formed by self-selective conjugate addition reactions.

    Donald L Elbert;Alison B Pratt;Matthias P Lutolf;Sven Halstenberg

  • Systematic Modulation of Michael-Type Reactivity of Thiols through the Use of Charged Amino Acids.

    M. P. Lutolf;N. Tirelli;S. Cerritelli;L. Cavalli

  • Biopolymeric delivery matrices for angiogenic growth factors

    Andreas H. Zisch;Matthias P. Lutolf;Matthias P. Lutolf;Jeffrey A. Hubbell;Jeffrey A. Hubbell

  • Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

    Leonardo Beccari;Naomi Moris;Mehmet Girgin;David A. Turner

Frequent Co-Authors

Jeffrey A. Hubbell
Jeffrey A. Hubbell New York University
Nicola Tirelli
Nicola Tirelli Italian Institute of Technology
Helen M. Blau
Helen M. Blau Stanford University
Johan Auwerx
Johan Auwerx École Polytechnique Fédérale de Lausanne
Wilfried Weber
Wilfried Weber University of Freiburg
Alfonso Martinez Arias
Alfonso Martinez Arias University of Cambridge
Tatiana V. Petrova
Tatiana V. Petrova University of Lausanne
Philippe Renaud
Philippe Renaud École Polytechnique Fédérale de Lausanne
George Coukos
George Coukos Cornell University
Marcus Textor
Marcus Textor ETH Zurich

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