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Genetics

D-Index
117
Citations
57301
World Ranking
424
National Ranking
221

Medicine

D-Index
118
Citations
58105
World Ranking
4028
National Ranking
2205

Overview

Alexander P. Reiner is affiliated with the University of Washington in the United States. Their research spans primarily the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on several subfields including Genetics, Molecular Biology, Hematology, Cardiology and Cardiovascular Medicine, and Epidemiology.

The scientist's recent scholarly output includes papers addressing complex genomic and biomolecular topics. Notable publications include:

  • Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data, 2022, Nature Genetics
  • Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging, 2021, Genome Biology
  • DNA methylation GrimAge version 2, 2022, Aging
  • Association of Clonal Hematopoiesis With Incident Heart Failure, 2021, Journal of the American College of Cardiology
  • Comparison of Proteomic Assessment Methods in Multiple Cohort Studies, 2020, PROTEOMICS

The research topics covered by Alexander P. Reiner reflect a strong expertise in genetic epidemiology and molecular biology aspects related to aging, cardiovascular disease, and proteomics. Key topics include:

  • Genetic Associations and Epidemiology
  • Epigenetics and DNA Methylation
  • Genomics and Rare Diseases
  • Acute Myeloid Leukemia Research
  • Hemoglobinopathies and Related Disorders
  • Cancer Genomics and Diagnostics
  • Bioinformatics and Genomic Networks

Their frequent collaborators highlight established scientific partnerships across multiple studies, with coauthors such as Laura M. Raffield, Jerome I. Rotter, Charles Kooperberg, Stephen S. Rich, and Bruce M. Psaty, with collaboration counts ranging from 48 to 85 publications each.

Alexander's work appears regularly in specific journals and publication venues, including:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation
  • Nature Communications
  • Journal of the American Heart Association

This profile reflects Alexander P. Reiner's active engagement in interdisciplinary biomedical research, focusing on leveraging genetic and molecular data to understand complex health conditions and biological mechanisms.

Best Publications

  • An epigenetic biomarker of aging for lifespan and healthspan

    Morgan E. Levine;Ake T. Lu;Austin Quach;Brian H. Chen

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose.

    Mark J. Rieder;Alexander P. Reiner;Brian F. Gage;Deborah A. Nickerson

  • DNA methylation GrimAge strongly predicts lifespan and healthspan.

    Ake T. Lu;Austin Quach;James G. Wilson;Alex P. Reiner

  • DNA methylation-based measures of biological age: meta-analysis predicting time to death

    Brian H. Chen;Riccardo E. Marioni;Riccardo E. Marioni;Elena Colicino;Marjolein J. Peters

  • The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

    D I Swerdlow;M V Holmes;K B Kuchenbaecker

  • Genetic analyses of diverse populations improves discovery for complex traits

    Genevieve L. Wojcik;Mariaelisa Graff;Katherine K. Nishimura;Ran Tao

  • Loss-of-function mutations in APOC3, triglycerides, and coronary disease

    Jacy Crosby;Gina M. Peloso;Gina M. Peloso;Paul L. Auer;David R. Crosslin

  • Association between alcohol and cardiovascular disease:Mendelian randomisation analysis based on individual participant data

    Michael V Holmes;Michael V Holmes;Caroline E Dale;Luisa Zuccolo;Richard J Silverwood

  • HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

    Daniel I Swerdlow;David Preiss;Karoline B Kuchenbaecker;Michael Holmes

  • An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

    Steve Horvath;Michael Gurven;Morgan E. Levine;Benjamin C. Trumble

  • Mendelian randomization of blood lipids for coronary heart disease

    Michael V. Holmes;Folkert W. Asselbergs;Tom M. Palmer;Fotios Drenos

  • Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

    Ron Do;Ron Do;Nathan O. Stitziel;Hong Hee Won;Hong Hee Won;Anders Berg Jørgensen

  • Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

    G. Eiriksdottir;T. B. Harris;L. J. Launer;V. Gudnason

  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

    Alexander G Bick;Joshua S Weinstock;Satish K Nandakumar;Satish K Nandakumar;Charles P Fulco;Charles P Fulco

  • The polygenic and monogenic basis of blood traits and diseases

    Dragana Vuckovic;Erik L. Bao;Parsa Akbari;Caleb A. Lareau

  • Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.

    Matthew Traylor;Martin Farrall;Elizabeth G Holliday;Cathie Sudlow

  • Inactivating mutations in NPC1L1 and protection from coronary heart disease

    Nathan O. Stitziel;Hong Hee Won;Alanna C. Morrison;Gina M. Peloso

  • Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

    Steve Horvath;Junko Oshima;Junko Oshima;George M. Martin;Ake T. Lu

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

Frequent Co-Authors

Bruce M. Psaty
Bruce M. Psaty University of Washington
Leslie A. Lange
Leslie A. Lange University of Colorado Anschutz Medical Campus
Charles Kooperberg
Charles Kooperberg Fred Hutchinson Cancer Research Center
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
James G. Wilson
James G. Wilson University of Mississippi Medical Center
Myriam Fornage
Myriam Fornage The University of Texas Health Science Center at Houston
Paul L. Auer
Paul L. Auer Medical College of Wisconsin
Ruth J. F. Loos
Ruth J. F. Loos University of Copenhagen
Kent D. Taylor
Kent D. Taylor David Geffen School of Medicine at UCLA

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