Arne N. Akbar

Research.com Recognitions

• Fellow of The Academy of Medical Sciences, United Kingdom
• Fellow of The Academy of Medical Sciences, United Kingdom
• Fellow of The Academy of Medical Sciences, United Kingdom
• Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Best Publications

• Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

  A. N. Akbar;L. Terry;A. Timms;P. C. L. Beverley

  1291
  Citations

• Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation.

  Christopher D Buckley;Darrell Pilling;Janet M Lord;Arne N Akbar

  723
  Citations

• CD28− T cells: their role in the age-associated decline of immune function

  Nan ping Weng;Arne N. Akbar;Jorg Goronzy

  695
  Citations

• Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin

  Karim Raza;Francesco Falciani;S John Curnow;Emma J Ross

  646
  Citations

• Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

  Milica Vukmanovic-Stejic;Yan Zhang;Joanne E. Cook;Jean M. Fletcher

  620
  Citations

• Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain.

  Helene M. Finney;Arne N. Akbar;Alastair D. G. Lawson

  614
  Citations

• Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population.

  Leonie S. Taams;Jay Smith;Malcolm H. Rustin;Mike Salmon

  606
  Citations

• RGD peptides induce apoptosis by direct caspase-3 activation

  Christopher D. Buckley;Darrell Pilling;Nick V. Henriquez;Greg Parsonage

  602
  Citations

• Are senescence and exhaustion intertwined or unrelated processes that compromise immunity

  Arne N. Akbar;Sian M. Henson

  565
  Citations

• Interleukin-2 receptor common γ-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression

  Arne N. Akbar;Nicola J. Borthwick;R. Gitendra Wickremasinghe;Panayiotis Panayiotidis

  520
  Citations

• Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition

  Branca I. Pereira;Oliver P. Devine;Milica Vukmanovic-Stejic;Emma S. Chambers

  503
  Citations

• Human immunosenescence : is it infectious?

  Graham Pawelec;Arne Akbar;Calogero Caruso;Rafael Solana

  490
  Citations

• Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial

  Edward S Chambers;Claire S Byrne;Douglas J Morrison;Kevin G Murphy

  454
  Citations

• The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory.

  A N Akbar;N Borthwick;M Salmon;W Gombert

  424
  Citations

• Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells

  Leonie S. Taams;Jocea M.R. van Amelsfort;Machteld M. Tiemessen;Kim M.G. Jacobs

  378
  Citations

• Inhibition of T cell apoptosis in the rheumatoid synovium.

  M Salmon;D Scheel-Toellner;A P Huissoon;D Pilling

  364
  Citations

• Is immunosenescence infectious

  Graham Pawelec;Arne Akbar;Calogero Caruso;Rita Effros

  363
  Citations

• Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion.

  Jean M. Fletcher;Milica Vukmanovic-Stejic;Padraic J. Dunne;Katie E. Birch;Katie E. Birch

  349
  Citations

• The synergy between naive and memory T cells during activation.

  Arne N. Akbar;Michael Salmon;George Janossy

  342
  Citations

• Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.

  Leonie S. Taams;Milica Vukmanovic-Stejic;Jay Smith;Padraic J. Dunne

  336
  Citations