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Immunology

D-Index
56
Citations
11695
World Ranking
3721
National Ranking
326

Overview

Leonie S. Taams is affiliated with King's College London in the United Kingdom. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a significant focus on subfields including Immunology, Rheumatology, Neurology, Oncology, and Physiology.

The scientist's work covers several main topics, notably:

  • Rheumatoid Arthritis Research and Therapies
  • T-cell and B-cell Immunology
  • Pain Mechanisms and Treatments
  • Psoriasis: Treatment and Pathogenesis
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Fibromyalgia and Chronic Fatigue Syndrome Research

They publish frequently in venues such as Clinical & Experimental Immunology and bioRxiv (Cold Spring Harbor Laboratory), each with 13 publications. Other notable venues include Pain, Lara D. Veeken, and Arthritis & Rheumatology.

Recent publications by Leonie S. Taams and frequent collaborators include:

  • "Interleukin-17 in rheumatoid arthritis: Trials and tribulations," 2020, The Journal of Experimental Medicine
  • "Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation," 2021, Nature Communications
  • "Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses," 2021, Journal of Extracellular Vesicles
  • "Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses," 2022, Brain
  • "Mechanisms of checkpoint inhibition-induced adverse events," 2020, Clinical & Experimental Immunology

Leonie S. Taams has collaborated often with Bruce Kirkham, Sarah Ryan, Zoe Rutter-Locher, Kirsty Bannister, and Franziska Denk.

Best Publications

  • CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages

    Machteld M. Tiemessen;Ann L. Jagger;Hayley G. Evans;Martijn J. C. van Herwijnen

  • CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid.

    Jocea M. R. van Amelsfort;Kim M. G. Jacobs;Johannes W. J. Bijlsma;Floris P. J. G. Lafeber

  • Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

    Milica Vukmanovic-Stejic;Yan Zhang;Joanne E. Cook;Jean M. Fletcher

  • Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population.

    Leonie S. Taams;Jay Smith;Malcolm H. Rustin;Mike Salmon

  • CD4+CD25bright Regulatory T Cells Actively Regulate Inflammation in the Joints of Patients with the Remitting Form of Juvenile Idiopathic Arthritis

    Ismé M. de Kleer;Lucy R. Wedderburn;Leonie S. Taams;Alka Patel

  • Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells

    Leonie S. Taams;Jocea M.R. van Amelsfort;Machteld M. Tiemessen;Kim M.G. Jacobs

  • Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.

    Leonie S. Taams;Milica Vukmanovic-Stejic;Jay Smith;Padraic J. Dunne

  • Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

    Hayley G. Evans;Tesha Suddason;Ian Jackson;Leonie S. Taams

  • Interleukin-17+CD8+T Cells Are Enriched in the Joints of Patients With Psoriatic Arthritis and Correlate With Disease Activity and Joint Damage Progression

    Bina Menon;Nicola J Gullick;Gina J Walter;Megha Rajasekhar

  • Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans.

    Charalambos Gustav Antoniades;Charalambos Gustav Antoniades;Alberto Quaglia;Leonie S. Taams;Ragai R. Mitry

  • The dynamic co-evolution of memory and regulatory CD4 + T cells in the periphery

    Arne N. Akbar;Milica Vukmanovic-Stejic;Leonie S. Taams;Derek C. Macallan

  • Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis

    Jocea M. R. van Amelsfort;Joel A. G. van Roon;Madelon Noordegraaf;Kim M. G. Jacobs

  • In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses.

    Hayley G. Evans;Nicola J. Gullick;Stephen Kelly;Costantino Pitzalis

  • The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis

    Ceri A. Roberts;Abigail K. Dickinson;Leonie S. Taams

  • Efficacy of birch‐pollen immunotherapy on cross‐reactive food allergy confirmed by skin tests and double‐blind food challenges

    S T H P Bolhaar;M M Tiemessen;L Zuidmeer;A van Leeuwen

  • Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4(+) T cells during aging

    Elaine Agius;Elaine Agius;Katie E. Lacy;Katie E. Lacy;Milica Vukmanovic-Stejic;Ann L. Jagger

  • Regulatory T cells in human disease and their potential for therapeutic manipulation

    Leonie S. Taams;Donald B. Palmer;Arne N. Akbar;Douglas S. Robinson

  • The presence, function and regulation of IL-17 and Th17 cells in periodontitis.

    Wan-Chien Cheng;Francis J. Hughes;Leonie S. Taams

  • Anergic T cells actively suppress T cell responses via the antigen‐presenting cell

    L. S. Taams;A. J. M. L. Van Rensen;M. C. M. Poelen;C. A. C. M. Van Els

  • IL-17 in the immunopathogenesis of spondyloarthritis

    Leonie S. Taams;Kathryn J. A. Steel;Ushani Srenathan;Lachrissa A. Burns

  • IL-17+ CD8+ T cells: Differentiation, phenotype and role in inflammatory disease.

    Ushani Srenathan;Kathryn Steel;Leonie S. Taams

Frequent Co-Authors

Arne N. Akbar
Arne N. Akbar University College London
Marca H. M. Wauben
Marca H. M. Wauben Utrecht University
Andrew P. Cope
Andrew P. Cope King's College London
Mike Salmon
Mike Salmon University of Birmingham
Graham M. Lord
Graham M. Lord University of Manchester
Willem van Eden
Willem van Eden Utrecht University
Frederic Geissmann
Frederic Geissmann Memorial Sloan Kettering Cancer Center
Costantino Pitzalis
Costantino Pitzalis Queen Mary University of London
Giovanna Lombardi
Giovanna Lombardi King's College London
Johannes W. J. Bijlsma
Johannes W. J. Bijlsma Utrecht University

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