World's Best Scientists 2026 revealed!
Sophia N. Karagiannis

Sophia N. Karagiannis

D-Index & Metrics

Immunology

D-Index
52
Citations
8285
World Ranking
4087
National Ranking
360

Overview

Sophia N. Karagiannis is affiliated with King's College London in the United Kingdom and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research spans several subfields, including Immunology, Oncology, Radiology, Nuclear Medicine and Imaging, Molecular Biology, and Immunology and Allergy.

The scientist's main topical focus covers areas such as Monoclonal and Polyclonal Antibodies Research, Mast cells and histamine, Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, T-cell and B-cell Immunology, and Immune Cell Function and Interaction.

Karagiannis has collaborated frequently with several coauthors, including Heather J. Bax, Jitesh Chauhan, James Spicer, Debra H. Josephs, and Alicia M. Chenoweth, reflecting ongoing partnerships in their research endeavors.

Their work has been published in a variety of scientific venues, with notable recurring contributions to:

  • Allergy
  • Cancers
  • Nature Communications
  • Clinical & Experimental Immunology
  • mAbs

Among their recent papers are:

  • Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action, 2021, European Journal of Immunology
  • Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance, 2020, Cancer Cell
  • Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients, 2021, Cancer Cell
  • WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion, 2020, Nature Communications
  • Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer, 2021, Cancer Research

Best Publications

  • Targeting folate receptor alpha for cancer treatment

    Anthony Cheung;Heather J. Bax;Debra H. Josephs;Kristina M. Ilieva

  • Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

    Chung-Ching Chu;Niwa Ali;Panagiotis Karagiannis;Paola Di Meglio

  • IgG4 subclass antibodies impair antitumor immunity in melanoma

    Panagiotis Karagiannis;Amy Gilbert;Debra Josephs;Niwa Ali

  • Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma.

    Duaa O. Khair;Heather J. Bax;Silvia Mele;Silvia Crescioli

  • AllergoOncology: the role of IgE-mediated allergy in cancer

    E Jensen-Jarolim;G Achatz;M C Turner;Sophia Karagiannis

  • Diverse matrix metalloproteinase functions regulate cancer amoeboid migration

    Jose L Orgaz;Pahini Pandya;Rimple Dalmeida;Panagiotis Karagiannis

  • Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action.

    Zena N Willsmore;Ben G T Coumbe;Silvia Crescioli;Sara Reci

  • Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs).

    Ricarda M Hoffmann;Ben G T Coumbe;Ben G T Coumbe;Debra H Josephs;Silvia Mele

  • Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment.

    Marigoula Georgouli;Cecilia Herraiz;Eva Crosas-Molist;Bruce Fanshawe

  • An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment

    Leena Halim;Marco Romano;Reuben McGregor;Isabel Correa

  • COMPARISON OF IGE AND IGG ANTIBODY-DEPENDENT CYTOTOXICITY IN VITRO AND IN A SCID MOUSE XENOGRAFT MODEL OF OVARIAN CARCINOMA

    Hannah J. Gould;Graham A. Mackay;Sophia N. Karagiannis;Carol M. O'Toole

  • IgE-Antibody-Dependent Immunotherapy of Solid Tumors: Cytotoxic and Phagocytic Mechanisms of Eradication of Ovarian Cancer Cells

    Sophia N. Karagiannis;Marguerite G. Bracher;James Hunt;Natalie McCloskey

  • Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance

    Jose L. Orgaz;Jose L. Orgaz;Eva Crosas-Molist;Eva Crosas-Molist;Amine Sadok;Anna Perdrix-Rosell;Anna Perdrix-Rosell;Anna Perdrix-Rosell

  • Activity of human monocytes in IgE antibody-dependent surveillance and killing of ovarian tumor cells

    Sophia N. Karagiannis;Qin Wang;Nick East;Frances Burke

  • TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination

    Gaia Cantelli;Jose L. Orgaz;Irene Rodriguez-Hernandez;Panagiotis Karagiannis

  • Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells

    Panagiotis Karagiannis;Josef Singer;James Hunt;Samuel K. E. Gan

  • A tool kit for rapid cloning and expression of recombinant antibodies

    Tihomir S. Dodev;Panagiotis Karagiannis;Amy E. Gilbert;Debra H. Josephs

  • Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types.

    Kristina M. Ilieva;Kristina M. Ilieva;Anthony Cheung;Anthony Cheung;Silvia Mele;Giulia Chiaruttini

  • Epidemiological associations of allergy, IgE and cancer.

    Debra H. Josephs;Debra H. Josephs;James F. Spicer;Christopher J. Corrigan;Hannah J. Gould

  • Revisiting the role of B cells in skin immune surveillance

    Isioma U. Egbuniwe;Sophia N. Karagiannis;Frank O. Nestle;Katie E. Lacy

  • Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients.

    Sultan Abdul-Jawad;Luca Baù;Thanussuyah Alaguthurai;Irene del Molino del Barrio

Frequent Co-Authors

Frank O. Nestle
Frank O. Nestle Deerfield (United States)
Hannah J. Gould
Hannah J. Gould King's College London
Erika Jensen-Jarolim
Erika Jensen-Jarolim Medical University of Vienna
Andrew Tutt
Andrew Tutt Institute of Cancer Research
Philip J. Blower
Philip J. Blower King's College London
Niklas Hammar
Niklas Hammar Karolinska Institute
Christopher Corrigan
Christopher Corrigan King's College London
David E. Thurston
David E. Thurston King's College London
Brian J. Sutton
Brian J. Sutton King's College London

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in Immunology but looking to diversify their careers in healthcare, several related online degree options can provide valuable pathways. Accelerated programs allow students to fast-track their education and enter the workforce sooner. For example, 12-month accelerated nursing programs online for non nurses are designed to help individuals without a nursing background become registered nurses quickly.

If you’re aiming for a Bachelor of Science in Nursing, exploring accelerated BSN programs for non nurses can be a practical approach. These accelerated BSN programs streamline prerequisites and clinical experiences to accommodate learners transitioning from other fields.

For those seeking a quicker entry point into nursing, it’s worth considering programs like which LPN programs are easiest to get into. Licensed Practical Nurse programs often have more flexible admissions and shorter durations, making them accessible options for many.

Finally, to advance clinical expertise and autonomy, one might look into the easiest nurse practitioner degree programs. These programs typically focus on removing barriers in admissions while maintaining quality education, allowing graduates to play critical roles in patient care and specialized services.

Best Scientists Citing Sophia N. Karagiannis

Trending Scientists

Recently Published Articles