World's Best Scientists 2026 revealed!
Award Badge
Immunology
Netherlands
2026
Award Badge
Medicine
Netherlands
2023

D-Index & Metrics

Immunology

D-Index
137
Citations
71698
World Ranking
177
National Ranking
5

Medicine

D-Index
139
Citations
72609
World Ranking
1761
National Ranking
64

Research.com Recognitions

  • 2026 - Research.com Immunology in Netherlands Leader Award
  • 2025 - Research.com Immunology in Netherlands Leader Award
  • 2023 - Research.com Medicine in Netherlands Leader Award
  • 2022 - Research.com Immunology in Netherlands Leader Award
  • 2012 - Member of Academia Europaea
  • 2008 - Royal Netherlands Academy of Arts and Sciences
  • 2006 - Spinoza Prize, Dutch Research Council

Overview

Carl G. Figdor is affiliated with Radboud University in the Netherlands. Their research spans several interconnected fields, predominantly focusing on Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Their work emphasizes the subfields of Immunology, Oncology, Molecular Biology, Radiology, Nuclear Medicine and Imaging, and Biomaterials.

The scientist's main research topics include:

  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Monoclonal and Polyclonal Antibodies Research
  • Cancer Immunotherapy and Biomarkers
  • T-cell and B-cell Immunology
  • Nanoparticle-Based Drug Delivery

Figdor has contributed to various scholarly articles published in notable venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal for ImmunoTherapy of Cancer
  • ACS Nano
  • OncoImmunology

Recent publications exemplify the scope and depth of their research:

  • PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up, 2021, International Journal of Pharmaceutics
  • Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity, 2021, Nature Communications
  • The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture, 2020, Nature Communications
  • Artificial Antigen-Presenting Cell Topology Dictates T Cell Activation, 2022, ACS Nano
  • Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial, 2020, Cancer Immunology Immunotherapy

Figdor collaborates frequently with several researchers, including:

  • I. Jolanda M. de Vries
  • Martijn Verdoes
  • Johannes Textor
  • Marjolein Schluck
  • Mark A.J. Gorris

The scientist has received multiple awards through their career, such as:

  • Member of Academia Europaea, 2012
  • Royal Netherlands Academy of Arts and Sciences, 2008
  • Spinoza Prize, Dutch Research Council, 2006

Best Publications

  • Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

    R de Waal Malefyt;J Abrams;B Bennett;C G Figdor

  • DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

    T.B.H. Geijtenbeek;D.S. Kwon;R. Torensma;S.J. van Vliet

  • Identification of DC-SIGN, a Novel Dendritic Cell–Specific ICAM-3 Receptor that Supports Primary Immune Responses

    T.B.H. Geijtenbeek;R. Torensma;S.J. van Vliet;G.C.F. van Duijnhoven

  • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

    R de Waal Malefyt;J Haanen;H Spits;M G Roncarolo

  • Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

    Katarina Wolf;Mariska te Lindert;Marina Krause;Stephanie Alexander

  • Dendritic cell immunotherapy: mapping the way

    Carl G Figdor;I Jolanda M de Vries;W Joost Lesterhuis;Cornelis J M Melief

  • C-type lectin receptors on dendritic cells and langerhans cells

    Carl G Figdor;Yvette van Kooyk;Gosse J Adema

  • Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy

    I Jolanda M de Vries;W Joost Lesterhuis;Jelle O Barentsz;Pauline Verdijk

  • Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting

    Paul J. Tacken;I. Jolanda M. de Vries;Ruurd Torensma;Carl G. Figdor

  • Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.

    R de Waal Malefyt;C G Figdor;R Huijbens;S Mohan-Peterson

  • The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells.

    Anneke Engering;Teunis B. H. Geijtenbeek;Sandra J. van Vliet;Mietske Wijers

  • Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes

    A.B.H. Bakker;M.W.J. Schreurs;A.J. de Boer;Y. Kawakami

  • Different faces of the heme-heme oxygenase system in inflammation

    Frank A. D. T. G. Wagener;Hans-Dieter Volk;Dean Willis;Nader G. Abraham

  • A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells

    G.J. Adema;F.C. Hartgers;R.G.G. Verstraten;E. de Vries

  • DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking

    T.B.H. Geijtenbeek;D.J.E.B. Krooshoop;D.A. Bleijs;S.J. van Vliet

  • Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state

    I. Jolanda M. de Vries;Daniëlle J. E. B. Krooshoop;Nicole M. Scharenborg;W. Joost Lesterhuis

  • Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes.

    Y van Kooyk;P van de Wiel-van Kemenade;P Weder;T W Kuijpers

  • In Situ Tumor Ablation Creates an Antigen Source for the Generation of Antitumor Immunity

    Martijn H. M. G. M. den Brok;Roger P. M. Sutmuller;Robbert van der Voort;Erik J. Bennink

  • Interleukin-4 (IL-4) inhibits secretion of IL-1 beta, tumor necrosis factor alpha, and IL-6 by human monocytes.

    A.A. te Velde;R.J.F. Huijbens;K. Heije;J.E. de Vries

  • Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase.

    Frank A. D. T. G. Wagener;Andreas Eggert;Otto C. Boerman;Wim J. G. Oyen

  • DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking

    T.B. Geijtenbeek;D.J.E.B. Krooshoop;D.A. Bleijs;S. van Vliet

Frequent Co-Authors

I. Jolanda M. de Vries
I. Jolanda M. de Vries Radboud University
Ruurd Torensma
Ruurd Torensma Radboud University
Gosse J. Adema
Gosse J. Adema Radboud University
Cornelis J. A. Punt
Cornelis J. A. Punt University of Amsterdam
Gerty Schreibelt
Gerty Schreibelt Radboud University
Vinod Subramaniam
Vinod Subramaniam Vrije Universiteit Amsterdam
Winald R. Gerritsen
Winald R. Gerritsen Radboud University
Yvette van Kooyk
Yvette van Kooyk Vrije Universiteit Amsterdam
Wim J.G. Oyen
Wim J.G. Oyen Humanitas University
Maria F. Garcia-Parajo
Maria F. Garcia-Parajo Institute of Photonic Sciences

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in immunology, pursuing related health care degrees can open diverse career paths. Many students complement their immunology knowledge with practical nursing programs that offer accelerated tracks. For example, choosing from the easiest accelerated nursing programs to get into helps students enter the workforce quickly while gaining essential clinical skills.

Another foundational route is enrolling in LPN programs, which provide a solid base in patient care and immunological health considerations. The lpn programs easy to get into are particularly attractive for those seeking quick access and hands-on experience in healthcare settings.

Advancing further, nurse practitioner degrees offer an excellent blend of clinical practice and patient management, some of which focus specifically on mental health. Students may find options through the easiest nurse practitioner program listings ideal for balancing study with professional growth.

For those aiming to specialize in psychiatric care within immunology-related contexts, exploring the best psychiatric mental health nurse practitioner programs online ensures valuable clinical placements and tailored training.

These pathways collectively support a robust foundation in immunology while enhancing professional opportunities in healthcare.

Best Scientists Citing Carl G. Figdor

Trending Scientists