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Gerty Schreibelt

Gerty Schreibelt

D-Index & Metrics

Immunology

D-Index
46
Citations
8547
World Ranking
4613
National Ranking
183

Overview

Gerty Schreibelt is affiliated with Radboud University in the Netherlands, focusing on research at the intersection of immunology and oncology. Their work contributes largely to the understanding of immune responses, particularly in the context of cancer immunotherapy.

Their primary fields of study are Immunology and Microbiology, with Medicine also being a significant area of their research portfolio. Subfields include Immunology, Oncology, Molecular Biology, Pathology and Forensic Medicine, and Pulmonary and Respiratory Medicine. Schreibelt's research addresses multiple main topics such as Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, T-cell and B-cell Immunology, vaccines and immunoinformatics approaches, RNA Interference and Gene Delivery, and Immune Cell Function and Interaction.

Schreibelt has contributed to a series of research papers published in prominent scientific venues. Some recent papers include:

  • Trial watch: Dendritic cell (DC)-based immunotherapy for cancer, 2022, OncoImmunology
  • What does cell therapy manufacturing cost? A framework and methodology to facilitate academic and other small-scale cell therapy manufacturing costings, 2020, Cytotherapy
  • Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial, 2020, Cancer Immunology Immunotherapy
  • Harnessing the cDC1-NK Cross-Talk in the Tumor Microenvironment to Battle Cancer, 2021, Frontiers in Immunology
  • Human pDCs Are Superior to cDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination, 2020, Cell Reports

Frequent collaborators in Schreibelt's research include:

  • I. Jolanda M. de Vries
  • Kalijn F. Bol
  • Carl G. Figdor
  • Mark A.J. Gorris
  • Georgina Flórez-Grau

The scientist's work has been published repeatedly in certain journals, highlighting ongoing contributions to these outlets. Frequent publication venues are:

  • OncoImmunology
  • Nature Communications
  • Cytotherapy
  • European Journal of Immunology
  • Frontiers in Immunology

Best Publications

  • Radical changes in multiple sclerosis pathogenesis.

    Jack van Horssen;Maarten E. Witte;Gerty Schreibelt;Helga E. de Vries

  • Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

    Gerty Schreibelt;Gijs Kooij;Arie Reijerkerk;Ruben van Doorn

  • Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients

    Jurjen Tel;Erik H.J.G. Aarntzen;Tetsuro Baba;Gerty Schreibelt

  • Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression

    J. van Horssen;G. Schreibelt;J. Drexhage;T. Hazes

  • Dendritic Cell–Based Immunotherapy: State of the Art and Beyond

    Kalijn F. Bol;Gerty Schreibelt;Winald R. Gerritsen;I. Jolanda M. de Vries

  • Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice

    W. Joost Lesterhuis;Cornelis J.A. Punt;Stanleyson V. Hato;Dagmar Eleveld-Trancikova

  • Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy

    Gerty Schreibelt;Jurjen Tel;Kwinten H. E. W. J. Sliepen;Daniel Benitez-Ribas

  • The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells.

    Gerty Schreibelt;Lieke J J Klinkenberg;Luis J Cruz;Paul J Tacken

  • Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells

    Gerty Schreibelt;Kalijn F. Bol;Harm Westdorp;Florian Wimmers

  • Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets

    Jurjen Tel;Gerty Schreibelt;Simone P. Sittig;Till S. M. Mathan

  • Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration

    A. C. Inge Boullart;Erik H. J. G. Aarntzen;Pauline Verdijk;Joannes F. M. Jacobs

  • Route of Administration Modulates the Induction of Dendritic Cell Vaccine–Induced Antigen-Specific T Cells in Advanced Melanoma Patients

    W. Joost Lesterhuis;I. Jolanda M. de Vries;Gerty Schreibelt;Annechien J.A. Lambeck

  • Lipoic Acid Affects Cellular Migration into the Central Nervous System and Stabilizes Blood-Brain Barrier Integrity

    Gerty Schreibelt;René J. P. Musters;Arie Reijerkerk;Lody R. de Groot

  • Paradigm Shift in Dendritic Cell-Based Immunotherapy: From in vitro Generated Monocyte-Derived DCs to Naturally Circulating DC Subsets.

    Florian Wimmers;Gerty Schreibelt;Annette E. Sköld;Carl G. Figdor

  • Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination

    Erik H.J.G. Aarntzen;I. Jolanda M. De Vries;W. Joost Lesterhuis;Danita Schuurhuis

  • The clinical application of cancer immunotherapy based on naturally circulating dendritic cells

    Kalijn F. Bol;Gerty Schreibelt;Katrin Rabold;Stefanie K. Wculek

  • Trial watch: Dendritic cell (DC)-based immunotherapy for cancer

    Unknown

  • Dendritic Cell Cancer Therapy: Vaccinating the Right Patient at the Right Time.

    Wouter W. van Willigen;Martine Bloemendal;Winald R. Gerritsen;Gerty Schreibelt

  • Targeting Uptake Receptors on Human Plasmacytoid Dendritic Cells Triggers Antigen Cross-Presentation and Robust Type I IFN Secretion

    Jurjen Tel;Simone P. Sittig;Rebecca A. M. Blom;Luis J. Cruz

  • Vaccination with mRNA-electroporated dendritic cells induces robust tumor antigen-specific CD4+ and CD8+ T cells responses in stage III and IV melanoma patients

    Erik H. J. G. Aarntzen;Gerty Schreibelt;Kalijn Bol;W. Joost Lesterhuis

  • Commonly used prophylactic vaccines as an alternative for synthetically produced TLR ligands to mature monocyte-derived dendritic cells.

    Gerty Schreibelt;Daniel Benitez-Ribas;Danita Schuurhuis;Annechien J. A. Lambeck

  • Immunogenicity of Dendritic Cells Pulsed with CEA Peptide or Transfected with CEA mRNA for Vaccination of Colorectal Cancer Patients

    W Joost Lesterhuis;I Jolanda M De Vries;G Schreibelt;Danita H Schuurhuis

Frequent Co-Authors

I. Jolanda M. de Vries
I. Jolanda M. de Vries Radboud University
Carl G. Figdor
Carl G. Figdor Radboud University
Cornelis J. A. Punt
Cornelis J. A. Punt University of Amsterdam
Winald R. Gerritsen
Winald R. Gerritsen Radboud University
Gosse J. Adema
Gosse J. Adema Radboud University
Helga E. de Vries
Helga E. de Vries University of Amsterdam
Christine D. Dijkstra
Christine D. Dijkstra VU University Medical Center
Wim J.G. Oyen
Wim J.G. Oyen Humanitas University
Jack van Horssen
Jack van Horssen Vrije Universiteit Amsterdam
Otto C. Boerman
Otto C. Boerman Radboud University

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