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Immunology

D-Index
90
Citations
29153
World Ranking
1076
National Ranking
38

Medicine

D-Index
91
Citations
29425
World Ranking
11789
National Ranking
455

Overview

Christine D. Dijkstra is affiliated with the VU University Medical Center in the Netherlands. Their research spans multiple disciplines, predominantly within the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Their scientific contributions focus largely on oncology and immunology, including molecular biology aspects.

The primary research areas explored by Christine Dijkstra include oncology, immunology, molecular biology, pulmonary and respiratory medicine, as well as pathology and forensic medicine. Their work also covers key topics in cancer immunotherapy and biomarkers, immune cell function and interaction, T-cell and B-cell immunology, the role of immune cells in cancer, cytokine signaling pathways and interactions, cancer mechanisms and therapy, and epigenetics and DNA methylation.

They have published extensively in several scientific journals, with frequent publication venues including:

  • Cancer Research
  • Cell Reports
  • STAR Protocols
  • Cancer Immunology Research
  • Journal of Clinical Oncology

Christine Dijkstra's recent papers encompass a range of contemporary cancer and immunology research topics:

  • TCF-1 limits intraepithelial lymphocyte antitumor immunity in colorectal carcinoma, 2023, Science Immunology
  • Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis, 2022, Cell Reports
  • Generation of gene-of-interest knockouts in murine organoids using CRISPR-Cas9, 2023, STAR Protocols
  • Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines, 2024, Cell Reports
  • Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within Interleukin-6 family cytokines, 2024, bioRxiv (Cold Spring Harbor Laboratory)

Collaborative work is also a significant component of Christine Dijkstra's research activity. Frequent co-authors include:

  • Matthias Ernst
  • Moritz F. Eissmann
  • Amr H. Allam
  • Anne Huber
  • Yang Liao

Best Publications

  • The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3.

    C D Dijkstra;E A Döpp;P Joling;G Kraal

  • Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1.

    J. G. M. C. Damoiseaux;E. A. Dopp;W. Calame;D. Chao

  • Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

    Daphne Y S Vogel;Elly J F Vereyken;Judith E Glim;Priscilla D A M Heijnen

  • Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages.

    I. Huitinga;N. Van Rooijen;C. J. A. De Groot;B. M. J. Uitdehaag

  • The macrophage scavenger receptor CD163

    Babs O Fabriek;Christine D Dijkstra;Timo K van den Berg

  • Human macrophage polarization in vitro: Maturation and activation methods compared

    Daphne Y.S. Vogel;Judith E. Glim;Andrea W.D. Stavenuiter;Marjolein Breur

  • The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria

    Babs O. Fabriek;Robin van Bruggen;Dong Mei Deng;Antoon J. M. Ligtenberg

  • Immune Invasion of the Central Nervous System Parenchyma and Experimental Allergic Encephalomyelitis, But Not Leukocyte Extravasation from Blood, Are Prevented in Macrophage-Depleted Mice

    E H Tran;K Hoekstra;N van Rooijen;C D Dijkstra

  • Homogeneity of active demyelinating lesions in established multiple sclerosis

    Esther C. W. Breij;Bianca P. Brink;Rob Veerhuis;Christa van den Berg

  • Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

    Gerty Schreibelt;Gijs Kooij;Arie Reijerkerk;Ruben van Doorn

  • Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression

    J. van Horssen;G. Schreibelt;J. Drexhage;T. Hazes

  • Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate.

    N. Van Rooijen;N. Kors;M. v. d. Ende;C. D. Dijkstra

  • Blood-brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis: a quantitative MRI study.

    S Floris;E L A Blezer;G Schreibelt;E Döpp

  • Biological markers in CSF and blood for axonal degeneration in multiple sclerosis

    Charlotte E Teunissen;Christine Dijkstra;Chris Polman

  • Regulation and Functional Involvement of Macrophage Scavenger Receptor MARCO in Clearance of Bacteria In Vivo

    L. J. W. Van Der Laan;E. A. Dopp;R. Haworth;T. Pikkarainen

  • Macrophages and neurodegeneration

    Jerome J.A. Hendriks;Charlotte E. Teunissen;Helga E. de Vries;Christine D. Dijkstra

  • Regulation of CD 163 on human macrophages: cross-linking of CD163 induces signaling and activation.

    M. M. Van Den Heuvel;C. P. Tensen;J. H. Van As;T. K. Van Den Berg

  • Signal-Regulatory Protein Is Selectively Expressed by Myeloid and Neuronal Cells

    S. Adams;L. J. W. Van Der Laan;E. Vernon-Wilson;C. Renardel De Lavalette

  • Immunocytochemical characterization of the expression of inducible and constitutive isoforms of nitric oxide synthase in demyelinating multiple sclerosis lesions.

    De Groot Cj;Ruuls;Theeuwes Jw;Dijkstra Cd

  • The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in rat recognized by monoclonal antibodies ED1, ED2 and ED3.

    C. D. Dijkstra;E. A. Döpp;P. Joling;G. Kraal

Frequent Co-Authors

Helga E. de Vries
Helga E. de Vries University of Amsterdam
Chris H. Polman
Chris H. Polman VU University Medical Center
Timo K. van den Berg
Timo K. van den Berg Radboud University
Sandra Amor
Sandra Amor University of Amsterdam
Paul van der Valk
Paul van der Valk Vrije Universiteit Amsterdam
Georg Kraal
Georg Kraal Vrije Universiteit Amsterdam
Jan Bauer
Jan Bauer Medical University of Vienna
Jack van Horssen
Jack van Horssen Vrije Universiteit Amsterdam

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