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Søren K. Moestrup

Søren K. Moestrup

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Biology and Biochemistry
Denmark
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
102
Citations
30074
World Ranking
1400
National Ranking
16

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Denmark Leader Award
  • 2022 - Research.com Biology and Biochemistry in Denmark Leader Award

Overview

Søren K. Moestrup is affiliated with Aarhus University in Denmark and has contributed extensively to research in medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their work spans various subfields including immunology, molecular biology, cell biology, neurology, and epidemiology.

The main topics addressed in their research include:

  • Immune cells in cancer
  • Hemoglobin structure and function
  • Neonatal health and biochemistry
  • Liver disease diagnosis and treatment
  • Phagocytosis and immune regulation
  • Erythrocyte function and pathophysiology
  • Neuroinflammation and neurodegeneration mechanisms

Recent publications by Søren K. Moestrup include:

  • Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer, 2020, The Journal of Experimental Medicine
  • Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases, 2020, International Journal of Molecular Sciences
  • APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin, 2020, Cell Reports
  • Hemolysis in the spleen drives erythrocyte turnover, 2020, Blood
  • Haemoglobin causes neuronal damage in vivo which is preventable by haptoglobin, 2020, Brain Communications

Frequent co-authors of Søren K. Moestrup include:

  • Jonas Heilskov Graversen
  • Anders Etzerodt
  • Maria Kløjgaard Skytthe
  • Pia Svendsen
  • Holger Jon Møller

Their work has appeared in various scientific venues, particularly:

  • Scientific Reports
  • Gastro Hep Advances
  • Scandinavian Journal of Clinical and Laboratory Investigation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Experimental Medicine

Best Publications

  • Identification of the haemoglobin scavenger receptor.

    Mette Kristiansen;Jonas H. Graversen;Christian Jacobsen;Ole Sonne

  • Identification of the receptor scavenging hemopexin-heme complexes

    Vibeke Hvidberg;Maciej B Maniecki;Maciej B Maniecki;Maciej B Maniecki;Christian Jacobsen;Christian Jacobsen;Christian Jacobsen;Peter Højrup

  • Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues.

    Søren K. Moestrup;Jørgen Gliemann;Gorm Pallesen

  • CD163 and inflammation: biological, diagnostic, and therapeutic aspects.

    Anders Etzerodt;Søren K Moestrup

  • CD163: a regulated hemoglobin scavenger receptor with a role in the anti‐inflammatory response

    Søren K Moestrup;Holger J Møller

  • MOLECULAR IDENTIFICATION OF A NOVEL CANDIDATE SORTING RECEPTOR PURIFIED FROM HUMAN BRAIN BY RECEPTOR-ASSOCIATED PROTEIN AFFINITY CHROMATOGRAPHY

    Claus M. Petersen;Morten S. Nielsen;Anders Nykjær;Linda Jacobsen

  • Vitamin B12 transport from food to the body's cells--a sophisticated, multistep pathway.

    Marianne Jensby Nielsen;Mie Rostved Rasmussen;Christian Brix Folsted Andersen;Ebba Nexø

  • Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs.

    S. K. Moestrup;Shiying Cui;H. Vorum;C. Bregengard

  • The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake

    Vibeke Hvidberg;Christian Jacobsen;Roland K. Strong;Jack B. Cowland

  • Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the α2-macroglobulin receptor

    Torsten Kristensen;Søren K. Moestrup;Jørgen Gliemann;Lone Bendtsen

  • The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.

    Renata Kozyraki;John Fyfe;Mette Kristiansen;Christian Gerdes

  • A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease

    Mercy R. PrabhuDas;Cynthia L. Baldwin;Paul L. Bollyky;Dawn M.E. Bowdish

  • Cubilin is an albumin binding protein important for renal tubular albumin reabsorption

    Henrik Birn;John C. Fyfe;Christian Jacobsen;Francoise Mounier

  • Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).

    Anders Nykjaer;John C. Fyfe;Renata Kozyraki;Jörg Robert Leheste

  • The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless.

    John C Fyfe;Mette Madsen;Peter Hojrup;Erik I Christensen

  • Megalin/gp330 mediates uptake of albumin in renal proximal tubule.

    S. Cui;P. J. Verroust;S. K. Moestrup;E. I. Christensen

  • CD163: a signal receptor scavenging haptoglobin-hemoglobin complexes from plasma.

    Jonas Heilskov Graversen;Mette Madsen;Søren K Moestrup

  • Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia

    Renata Kozyraki;John Fyfe;Pierre J. Verroust;Christian Jacobsen

  • Molecular Characterization of a Novel Human Hybrid-type Receptor That Binds the α2-Macroglobulin Receptor-associated Protein

    Linda Jacobsen;Peder Madsen;Søren K. Moestrup;Anders H. Lund

  • Identification of the receptor scavenging hemopexin-heme complexes. Commentary

    Vibeke Hvidberg;Maciej B. Maniecki;Christian Jacobsen;Peter Højrup

Frequent Co-Authors

Christian Jacobsen
Christian Jacobsen Aarhus University
Pierre J. Verroust
Pierre J. Verroust Aarhus University
Erik Ilsø Christensen
Erik Ilsø Christensen Aarhus University
Jørgen Gliemann
Jørgen Gliemann Aarhus University
Ebba Nexo
Ebba Nexo Aarhus University Hospital
Lars Sottrup-Jensen
Lars Sottrup-Jensen Aarhus University
Bent Deleuran
Bent Deleuran Aarhus University Hospital
Thomas E. Willnow
Thomas E. Willnow Max Delbrück Center for Molecular Medicine
Anders Nykjaer
Anders Nykjaer Aarhus University
Toby Lawrence
Toby Lawrence King's College London

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