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Biology and Biochemistry

D-Index
74
Citations
17847
World Ranking
5652
National Ranking
2680

Overview

Steven L. Gonias is affiliated with the University of California, San Diego in the United States. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in multiple subfields including Molecular Biology, Infectious Diseases, Cellular and Molecular Neuroscience, Immunology, and Biomedical Engineering.

The scientist's research topics cover a range of areas such as SARS-CoV-2 and COVID-19 Research, SARS-CoV-2 detection and testing, Nerve injury and regeneration, Prion Diseases and Protein Misfolding, Extracellular vesicles in disease, Signaling Pathways in Disease, and Biosensors and Analytical Detection.

Frequent co-authors collaborating with Steven L. Gonias include Pardis Azmoon, Elisabetta Mantuano, Ronald W. McLawhon, W. Marie Campana, and Michael A. Banki.

Steven L. Gonias has published in a variety of scientific journals, predominantly in bioRxiv (Cold Spring Harbor Laboratory), the Journal of Biological Chemistry, Glia, American Journal of Pathology, and Nature.

Recent papers authored or co-authored by Steven L. Gonias include:

  • Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission, 2022, Nature
  • Plasminogen activator receptor assemblies in cell signaling, innate immunity, and inflammation, 2021, American Journal of Physiology-Cell Physiology
  • SARS-CoV-2 Serology Status Detected by Commercialized Platforms Distinguishes Previous Infection and Vaccination Adaptive Immune Responses, 2021, The Journal of Applied Laboratory Medicine
  • Deletion of the Gene Encoding the NMDA Receptor GluN1 Subunit in Schwann Cells Causes Ultrastructural Changes in Remak Bundles and Hypersensitivity in Pain Processing, 2020, Journal of Neuroscience
  • A soluble derivative of PrPC activates cell-signaling and regulates cell physiology through LRP1 and the NMDA receptor, 2020, Journal of Biological Chemistry

Best Publications

  • Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin

    Jun Li Luo;Wei Tan;Jill M. Ricono;Olexandr Korchynskyi

  • A new procedure for the synthesis of polyethylene glycol-protein adducts; effects on function, receptor recognition, and clearance of superoxide dismutase, lactoferrin, and alpha 2-macroglobulin.

    Charles O. Beauchamp;Charles O. Beauchamp;Steven L. Gonias;David P. Menapace;David P. Menapace;Salvatore V. Pizzo

  • Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner.

    Diem H.D. Nguyen;Andrew D. Catling;Donna J. Webb;Mauricio Sankovic

  • High-resolution imaging of the dynamic tumor cell vascular interface in transparent zebrafish.

    Konstantin Stoletov;Valerie Montel;Robin D. Lester;Steven L. Gonias

  • Diverse roles for the LDL receptor family

    Dudley K. Strickland;Steven L. Gonias;W.Scott Argraves

  • uPAR induces epithelial–mesenchymal transition in hypoxic breast cancer cells

    Robin D. Lester;Minji Jo;Valérie Montel;Shinako Takimoto

  • Cytokine binding and clearance properties of proteinase-activated alpha 2-macroglobulins.

    J LaMarre;G K Wollenberg;S L Gonias;M A Hayes

  • Binding of Urokinase-type Plasminogen Activator to Its Receptor in MCF-7 Cells Activates Extracellular Signal-regulated Kinase 1 and 2 Which Is Required for Increased Cellular Motility

    Diem H.D. Nguyen;Isa M. Hussaini;Steven L. Gonias

  • Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression.

    Kebin Hu;Junwei Yang;Sakae Tanaka;Steven L. Gonias

  • Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain.

    B. B. Wolf;M. B. S. Lopes;S. R. Vandenberg;S. L. Gonias

  • Physical properties of human α2-macroglobulin following reaction with methylamine and trypsin

    Steven L. Gonias;Jacqueline A. Reynolds;Salvatore V. Pizzo

  • Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion.

    D.J. Webb;D.H. Nguyen;S.L. Gonias

  • LDL Receptor–Related Protein-1: A Regulator of Inflammation in Atherosclerosis, Cancer, and Injury to the Nervous System

    Steven L. Gonias;W. Marie Campana

  • Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell-signaling

    Minji Jo;Robin D. Lester;Valerie Montel;Boryana Eastman

  • Urokinase-type Plasminogen Activator Stimulates the Ras/Extracellular Signal-regulated Kinase (ERK) Signaling Pathway and MCF-7 Cell Migration by a Mechanism That Requires Focal Adhesion Kinase, Src, and Shc RAPID DISSOCIATION OF GRB2/SOS-SHC COMPLEX IS ASSOCIATED WITH THE TRANSIENT PHOSPHORYLATION OF ERK IN UROKINASE-TREATED CELLS

    Diem H.D. Nguyen;Donna J. Webb;Andrew D. Catling;Qian Song

  • Effects of bacterial lipopolysaccharide on the hydrolysis of phosphatidylinositol-4,5-bisphosphate in murine peritoneal macrophages

    V Prpic;J E Weiel;S D Somers;J DiGuiseppi

  • The Hemopexin Domain of Matrix Metalloproteinase-9 Activates Cell Signaling and Promotes Migration of Schwann Cells by Binding to Low-Density Lipoprotein Receptor-Related Protein

    Elisabetta Mantuano;Gen Inoue;Xiaoqing Li;Kazuhisa Takahashi

  • Inhibition of cell surface receptor-bound plasmin by alpha 2-antiplasmin and alpha 2-macroglobulin.

    S W Hall;J E Humphries;S L Gonias

  • Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization.

    Chad E. Green;Tiffany Liu;Valerie Montel;Gene Hsiao

  • Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin (Nature (2007) 446, (690-694))

    Jun Li Luo;Wei Tan;Jill M. Ricono;Olexandr Korchynskyi

Frequent Co-Authors

Salvatore V. Pizzo
Salvatore V. Pizzo Duke University
Donna J. Webb
Donna J. Webb Vanderbilt University
Scott R. VandenBerg
Scott R. VandenBerg University of California, San Francisco
W. Marie Campana
W. Marie Campana University of California, San Diego
Alissa M. Weaver
Alissa M. Weaver Vanderbilt University
Frank B. Furnari
Frank B. Furnari University of California, San Diego
Webster K. Cavenee
Webster K. Cavenee University of California, San Diego
Richard L. Klemke
Richard L. Klemke University of California, San Diego
Steven R. Feldman
Steven R. Feldman Wake Forest University
Dudley K. Strickland
Dudley K. Strickland American Red Cross

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