World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
24307
World Ranking
5504
National Ranking
2615

Overview

Frank B. Furnari is affiliated with the University of California, San Diego in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with a significant portion of work also in Medicine. Within these domains, the subfields of Molecular Biology, Genetics, Cancer Research, Immunology, and Cell Biology are prominently represented in their publication record.

The scientist's main research topics include Glioma Diagnosis and Treatment, Protein Degradation and Inhibitors, Cancer Genomics and Diagnostics, MicroRNA in disease regulation, Cancer, Hypoxia, and Metabolism, Single-cell and spatial transcriptomics, and RNA Research and Splicing.

Frequent venues for Frank B. Furnari's publications include:

  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • UNC Libraries
  • Neuro-Oncology Advances

Notable recent papers authored or co-authored by Furnari encompass:

  • Integrin αvβ5 Internalizes Zika Virus during Neural Stem Cells Infection and Provides a Promising Target for Antiviral Therapy, 2020, Cell Reports
  • Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug, 2021, Cell Reports
  • PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response, 2021, Proceedings of the National Academy of Sciences
  • Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer, 2021, Science Advances
  • Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas, 2020, EBioMedicine

Frequent co-authors collaborating with Furnari include:

  • Tomoyuki Koga
  • Shunichiro Miki
  • Clark C. Chen
  • C. Ryan Miller
  • Benjamin Lin

Best Publications

  • Malignant astrocytic glioma: genetics, biology, and paths to treatment.

    Frank B. Furnari;Tim Fenton;Robert M. Bachoo;Akitake Mukasa

  • Malignant glioma: Genetics and biology of a grave matter

    Elizabeth A. Maher;Frank B. Furnari;Robert M. Bachoo;David H. Rowitch

  • PHLPP: A Phosphatase that Directly Dephosphorylates Akt, Promotes Apoptosis, and Suppresses Tumor Growth

    Tianyan Gao;Frank Furnari;Alexandra C. Newton

  • Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

    Kristen M. Turner;Viraj Deshpande;Doruk Beyter;Tomoyuki Koga

  • Emerging insights into the molecular and cellular basis of glioblastoma

    Gavin P. Dunn;Mikael L. Rinne;Mikael L. Rinne;Jill Wykosky;Giannicola Genovese

  • Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

    John C. Sok;Francesca M. Coppelli;Sufi M. Thomas;Miriam N. Lango

  • Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

    Maria-del-Mar Inda;Rudy Bonavia;Akitake Mukasa;Akitake Mukasa;Yoshitaka Narita

  • Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.

    David A. Nathanson;Beatrice Gini;Jack Mottahedeh;Koppany Visnyei

  • Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

    Frank B. Furnari;Hong Lin;H.-J. Su Huang;Webster K. Cavenee

  • The Phosphoinositol Phosphatase Activity of PTEN Mediates a Serum-sensitive G1 Growth Arrest in Glioma Cells

    Frank B. Furnari;H-J. Su Huang;Webster K. Cavenee

  • Heterogeneity maintenance in glioblastoma: a social network.

    Rudy Bonavia;Maria-del-Mar Inda;Webster K. Cavenee;Frank B. Furnari

  • Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma.

    Paul H. Huang;Akitake Mukasa;Rudy Bonavia;Ryan A. Flynn

  • Circular ecDNA promotes accessible chromatin and high oncogene expression

    Sihan Wu;Kristen M. Turner;Nam Nguyen;Ramya Raviram

  • Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma

    Frank B. Furnari;Timothy F. Cloughesy;Webster K. Cavenee;Paul S. Mischel

  • Dynamics of Centromere and Kinetochore Proteins: Implications for Checkpoint Signaling and Silencing

    Jagesh V Shah;Elliot Botvinick;Elliot Botvinick;Zahid Bonday;Frank Furnari

  • Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor

    Corina E. Antal;Andrew M. Hudson;Emily Kang;Ciro Zanca

  • EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in Glioblastoma

    Bipasha Mukherjee;Brian McEllin;Cristel V. Camacho;Nozomi Tomimatsu

  • Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance.

    Tiffany E. Taylor;Frank B. Furnari;Webster K. Cavenee

  • An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers

    Genaro R. Villa;Jonathan J. Hulce;Ciro Zanca;Junfeng Bi

  • PCAF Modulates PTEN Activity

    Koichi Okumura;Michelle Mendoza;Robert M. Bachoo;Ronald A. DePinho

Frequent Co-Authors

Webster K. Cavenee
Webster K. Cavenee University of California, San Diego
Paul S. Mischel
Paul S. Mischel Stanford University
Bob S. Carter
Bob S. Carter Harvard University
Scott R. VandenBerg
Scott R. VandenBerg University of California, San Francisco
Ronald A. DePinho
Ronald A. DePinho The University of Texas MD Anderson Cancer Center
Michael E. Berens
Michael E. Berens Translational Genomics Research Institute
Terrance Grant Johns
Terrance Grant Johns Telethon Kids Institute
Cameron Brennan
Cameron Brennan Memorial Sloan Kettering Cancer Center
Lynda Chin
Lynda Chin The University of Texas Health Science Center at Houston
Kelly A. Frazer
Kelly A. Frazer University of California, San Diego

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Biology or Biochemistry can open doors to allied health careers, especially in fields like medical coding, billing, and health information management. With healthcare rapidly digitizing, there is growing demand for professionals equipped to handle sensitive records and medical data.

If you’re curious about earning potential, explore the ccs vs cpc salary details to compare credentials and job opportunities. Becoming a certified medical coder is a popular path; discover what you can expect in terms of certified medical coder salary and job outlook.

Wondering if this career choice is right for you? Review the benefits and challenges in the guide is medical coding a good career. For those seeking flexible study options, explore the online health information management degree programs that offer affordability and accessibility.

These pathways can blend your science background with essential healthcare skills, leading to rewarding and stable careers.

Best Scientists Citing Frank B. Furnari

Trending Scientists

Recently Published Articles