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Medicine

D-Index
143
Citations
71666
World Ranking
1518
National Ranking
881

Overview

Timothy F. Cloughesy is affiliated with the University of California, Los Angeles in the United States. Their research primarily focuses on medical fields with a strong emphasis on glioma diagnosis and treatment, radiomics and machine learning in medical imaging, and various cancer-related areas.

Cloughesy's work covers several main fields of study, including Medicine and Biochemistry, Genetics and Molecular Biology. Their subfields of study encompass Genetics, Radiology, Nuclear Medicine and Imaging, Cancer Research, Molecular Biology, and Pulmonary and Respiratory Medicine.

The main topics of their research include:

  • Glioma Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • MRI in cancer diagnosis
  • Cancer, Hypoxia, and Metabolism
  • Medical Imaging Techniques and Applications
  • Cancer Genomics and Diagnostics
  • Advanced MRI Techniques and Applications

Among recent publications attributed to their research domain are:

  • Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions, 2020, Neuro-Oncology
  • Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma, 2023, New England Journal of Medicine
  • Radiotherapy combined with nivolumab or temozolomide for newly diagnosed glioblastoma with unmethylated MGMT promoter: An international randomized phase III trial, 2022, Neuro-Oncology
  • RANO 2.0: Update to the Response Assessment in Neuro-Oncology Criteria for High- and Low-Grade Gliomas in Adults, 2023, Journal of Clinical Oncology
  • Federated learning enables big data for rare cancer boundary detection, 2022, Nature Communications

Frequent publication venues for Cloughesy include:

  • Neuro-Oncology
  • Journal of Clinical Oncology
  • Neuro-Oncology Advances
  • Journal of Neuro-Oncology
  • Nature Communications

The scientist has collaborated frequently with several co-authors such as:

  • Benjamin M. Ellingson
  • Patrick Y. Wen
  • Phioanh L. Nghiemphu
  • Linda M. Liau
  • Catalina Raymond

Best Publications

  • Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group

    Patrick Y. Wen;David R. Macdonald;David A. Reardon;Timothy F. Cloughesy

  • Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma

    Henry S. Friedman;Michael D. Prados;Patrick Y. Wen;Tom Mikkelsen

  • Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma

    Olivier L. Chinot;Wolfgang Wick;Warren Mason;Roger Henriksson

  • Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

    Ingo K. Mellinghoff;Maria Y. Wang;Igor Vivanco;Daphne A. Haas-Kogan

  • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

    Rameen Beroukhim;Gad Getz;Leia Nghiemphu;Jordi Barretina

  • High-throughput oncogene mutation profiling in human cancer

    Roman K. Thomas;Alissa C. Baker;Ralph M. DeBiasi;Ralph M. DeBiasi;Wendy Winckler;Wendy Winckler

  • Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma.

    Timothy F. Cloughesy;Aaron Y. Mochizuki;Joey R. Orpilla;Willy Hugo

  • Gene Expression Profiling of Gliomas Strongly Predicts Survival

    William A. Freije;F. Edmundo Castro-Vargas;Zixing Fang;Steve Horvath

  • Standards of care for treatment of recurrent glioblastoma—are we there yet?

    Michael Weller;Timothy Cloughesy;James R. Perry;Wolfgang Wick

  • Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions

    Patrick Y. Wen;Michael Weller;Eudocia Quant Lee;Brian M. Alexander

  • Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target

    S. Horvath;B. Zhang;M. Carlson;K. V. Lu

  • Consensus recommendations for a standardized Brain Tumor Imaging Protocol in clinical trials

    Benjamin M. Ellingson;Martin Bendszus;Martin Bendszus;Jerrold Boxerman;Daniel Barboriak

  • Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma

    Tim F Cloughesy;Koji Yoshimoto;Phioanh Leia Nghiemphu;Kevin Brown

  • Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment

    Linda M. Liau;Robert M. Prins;Sylvia M. Kiertscher;Sylvia K. Odesa

  • Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.

    David A. Nathanson;Beatrice Gini;Jack Mottahedeh;Koppany Visnyei

  • Randomized Phase II Study of Cilengitide, an Integrin-Targeting Arginine-Glycine-Aspartic Acid Peptide, in Recurrent Glioblastoma Multiforme

    David A. Reardon;Karen L. Fink;Tom Mikkelsen;Timothy F. Cloughesy

  • Glioblastoma: From Molecular Pathology to Targeted Treatment

    Timothy F. Cloughesy;Webster K. Cavenee;Paul S. Mischel

  • Analysis of the Phosphatidylinositol 3′-Kinase Signaling Pathway in Glioblastoma Patients in Vivo

    Gheeyoung Choe;Steve Horvath;Timothy F. Cloughesy;Katherine Crosby

  • Phase II Study of Bevacizumab Plus Temozolomide During and After Radiation Therapy for Patients With Newly Diagnosed Glioblastoma Multiforme

    Albert Lai;Anh Tran;Phioanh L. Nghiemphu;Whitney B. Pope

  • Imaging Proliferation in Brain Tumors with 18F-FLT PET: Comparison with 18F-FDG

    Wei Chen;Timothy Cloughesy;Nirav Kamdar;Nagichettiar Satyamurthy

Frequent Co-Authors

Albert Lai
Albert Lai University of Washington
Linda M. Liau
Linda M. Liau University of California, Los Angeles
Patrick Y. Wen
Patrick Y. Wen Harvard University
Paul S. Mischel
Paul S. Mischel Stanford University
David A. Reardon
David A. Reardon Harvard University
Michael D. Prados
Michael D. Prados University of California, San Francisco
Ingo K. Mellinghoff
Ingo K. Mellinghoff Memorial Sloan Kettering Cancer Center
Susan M. Chang
Susan M. Chang University of California, San Francisco
Wolfgang Wick
Wolfgang Wick German Cancer Research Center
Lisa M. DeAngelis
Lisa M. DeAngelis Memorial Sloan Kettering Cancer Center

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