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Karl-Norbert Klotz

Karl-Norbert Klotz

University of Würzburg
Germany

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
13767
World Ranking
12443
National Ranking
887

Karl-Norbert Klotz publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Karl-Norbert Klotz sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 229 publications — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Karl-Norbert Klotz D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Karl-Norbert Klotz sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 59 D-Index — 38th percentile

38% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Karl-Norbert Klotz is affiliated with the University of Würzburg in Germany. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a strong emphasis on subfields such as Physiology, Molecular Biology, and Organic Chemistry. Additional areas of specialization include Pulmonary and Respiratory Medicine as well as Materials Chemistry.

The main topics addressed in their work focus on Adenosine and Purinergic Signaling, Pharmacological Receptor Mechanisms and Effects, and Receptor Mechanisms and Signaling. They also explore Synthesis and Biological Evaluation, Click Chemistry and Applications, Respiratory and Cough-Related Research, and Advanced biosensing and bioanalysis techniques.

Key recent publications by Karl-Norbert Klotz include:

  • Pharmacological characterisation of novel adenosine A3 receptor antagonists, 2020, Scientific Reports
  • Adenosine Receptor Ligands: Coumarin-Chalcone Hybrids as Modulating Agents on the Activity of hARs, 2020, Molecules
  • A2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable?, 2022, Molecules
  • Bronchospasmolytic activity and adenosine receptor binding of some newer 1,3-dipropyl-8-phenyl substituted xanthine derivatives, 2020, Chemical Biology & Drug Design
  • Targeting G Protein-Coupled Receptors with Magnetic Carbon Nanotubes: The Case of the A3 Adenosine Receptor, 2020, ChemMedChem

Frequent co-authors collaborating with Klotz include Sonja Kachler, Stephanie Federico, Giampiero Spalluto, Stefano Moro, and Andrea Spinaci. Their work is often published in venues such as the IUPHAR/BPS Guide to Pharmacology CITE, Molecules, ChemMedChem, Current Drug Discovery Technologies, and Scientific Reports.

Best Publications

  • International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors

    Bertil B. Fredholm;Adriaan P. IJzerman;Kenneth A. Jacobson;Karl-Norbert Klotz

  • Comparative pharmacology of human adenosine receptor subtypes – characterization of stably transfected receptors in CHO cells

    K N Klotz;J Hessling;J Hegler;Christer Owman

  • 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX)--a selective high affinity antagonist radioligand for A1 adenosine receptors.

    Martin J. Lohse;Karl-Norbert Klotz;Jutta Lindenborn-Fotinos;Martin Reddington

  • Adenosine receptors and their ligands.

    Karl-Norbert Klotz

  • Analysis of receptor oligomerization by FRAP microscopy.

    Sandra Dorsch;Karl-Norbert Klotz;Stefan Engelhardt;Martin J Lohse

  • Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity

    Sebastian F. M. Häusler;Itsaso Montalbán del Barrio;Jenny Strohschein;P. Anoop Chandran

  • 2-Chloro-N6-cyclopentyladenosine: a highly selective agonist at A1 adenosine receptors.

    Martin J. Lohse;Karl-Norbert Klotz;Ulrich Schwabe;Gloria Cristalli

  • The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion.

    Michael P. Schön;Margarete Schön;Karl-Norbert Klotz

  • Water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, A2A-Selective adenosine receptor antagonists

    Roland Sauer;Juris Maurinsh;Ulrike Reith;Friederike Fülle

  • Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells.

    Stefania Merighi;Prisco Mirandola;Prisco Mirandola;Daniela Milani;Katia Varani

  • 2-Chloro-N6-[3H]cyclopentyladenosine ([3H]CCPA)--a high affinity agonist radioligand for A1 adenosine receptors.

    Karl-Norbert Klotz;Martin J. Lohse;Ulrich Schwabe;Gloria Cristalli

  • [(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.

    Katia Varani;Stefania Merighi;Stefania Gessi;Karl-Norbert Klotz

  • Adenosine receptors and cancer.

    P. Fishman;S. Bar-Yehuda;M. Synowitz;J.D. Powell

  • 2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors.

    Gloria Cristalli;Alessandra Eleuteri;Sauro Vittori;Rosaria Volpini

  • Adenosine A1 receptor-mediated activation of phospholipase C in cultured astrocytes depends on the level of receptor expression

    Knut Biber;KN Klotz;M Berger;PJ GebickeHarter

  • Photoaffinity labeling of A1-adenosine receptors.

    K N Klotz;G Cristalli;M Grifantini;S Vittori

  • N(6)-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting point for searching A(2B) ligands.

    Rosaria Volpini;Stefano Costanzi;Catia Lambertucci;Sara Taffi

  • Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonists.

    Pier Giovanni Baraldi;Barbara Cacciari;Stefano Moro;Giampiero Spalluto

  • Synthesis of new delta 2-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic receptor antagonists.

    Paola Conti;Clelia Dallanoce;Marco De Amici;Carlo De Micheli

  • [3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors.

    Stefania Gessi;Katia Varani;Stefania Merighi;K. N. Klotz

Frequent Co-Authors

Martin J. Lohse
Martin J. Lohse ISAR Bioscience Institute
Stefano Moro
Stefano Moro University of Padua
Sauro Vittori
Sauro Vittori University of Camerino
Maria João Matos
Maria João Matos University of Santiago de Compostela
Pier Giovanni Baraldi
Pier Giovanni Baraldi University of Ferrara
Antonio Lavecchia
Antonio Lavecchia University of Naples Federico II
Claudia Martini
Claudia Martini University of Pisa
Eugenio Uriarte
Eugenio Uriarte University of Santiago de Compostela
Stefania Gessi
Stefania Gessi University of Ferrara
Pier Andrea Borea
Pier Andrea Borea University of Ferrara

External Links

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Best Scientists Citing Karl-Norbert Klotz

Kenneth A. Jacobson

Kenneth A. Jacobson

National Institutes of Health

Publications: 163

Katia Varani

Katia Varani

University of Ferrara

Publications: 131

Pier Andrea Borea

Pier Andrea Borea

University of Ferrara

Publications: 122

Christa E. Müller

Christa E. Müller

University of Bonn

Publications: 114

Bertil B. Fredholm

Bertil B. Fredholm

Karolinska Institute

Publications: 86

Adriaan P. IJzerman

Adriaan P. IJzerman

Leiden University

Publications: 78

Zhan-Guo Gao

Zhan-Guo Gao

National Institutes of Health

Publications: 77

Stefania Gessi

Stefania Gessi

University of Ferrara

Publications: 71

Joel Linden

Joel Linden

University of Virginia

Publications: 69

Michael R. Blackburn

Michael R. Blackburn

The University of Texas Health Science Center at Houston

Publications: 66

Stefania Merighi

Stefania Merighi

University of Ferrara

Publications: 66

Pier Giovanni Baraldi

Pier Giovanni Baraldi

University of Ferrara

Publications: 63

Martin J. Lohse

Martin J. Lohse

ISAR Bioscience Institute

Publications: 52

Rafael Franco

Rafael Franco

University of Barcelona

Publications: 47

Ana M. Sebastião

Ana M. Sebastião

University of Lisbon

Publications: 46

György Haskó

György Haskó

Columbia University

Publications: 46

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