Karl-Norbert Klotz

Overview

Best Publications

• International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors

  Bertil B. Fredholm;Adriaan P. IJzerman;Kenneth A. Jacobson;Karl-Norbert Klotz

  3394
  Citations

• Comparative pharmacology of human adenosine receptor subtypes – characterization of stably transfected receptors in CHO cells

  K N Klotz;J Hessling;J Hegler;Christer Owman

  784
  Citations

• 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX)--a selective high affinity antagonist radioligand for A1 adenosine receptors.

  Martin J. Lohse;Karl-Norbert Klotz;Jutta Lindenborn-Fotinos;Martin Reddington

  499
  Citations

• Adenosine receptors and their ligands.

  Karl-Norbert Klotz

  458
  Citations

• Analysis of receptor oligomerization by FRAP microscopy.

  Sandra Dorsch;Karl-Norbert Klotz;Stefan Engelhardt;Martin J Lohse

  280
  Citations

• Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity

  Sebastian F. M. Häusler;Itsaso Montalbán del Barrio;Jenny Strohschein;P. Anoop Chandran

  237
  Citations

• 2-Chloro-N6-cyclopentyladenosine: a highly selective agonist at A1 adenosine receptors.

  Martin J. Lohse;Karl-Norbert Klotz;Ulrich Schwabe;Gloria Cristalli

  234
  Citations

• The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion.

  Michael P. Schön;Margarete Schön;Karl-Norbert Klotz

  215
  Citations

• Water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, A2A-Selective adenosine receptor antagonists

  Roland Sauer;Juris Maurinsh;Ulrike Reith;Friederike Fülle

  210
  Citations

• Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells.

  Stefania Merighi;Prisco Mirandola;Prisco Mirandola;Daniela Milani;Katia Varani

  189
  Citations

• 2-Chloro-N6-[3H]cyclopentyladenosine ([3H]CCPA)--a high affinity agonist radioligand for A1 adenosine receptors.

  Karl-Norbert Klotz;Martin J. Lohse;Ulrich Schwabe;Gloria Cristalli

  183
  Citations

• [(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.

  Katia Varani;Stefania Merighi;Stefania Gessi;Karl-Norbert Klotz

  179
  Citations

• Adenosine receptors and cancer.

  P. Fishman;S. Bar-Yehuda;M. Synowitz;J.D. Powell

  172
  Citations

• 2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors.

  Gloria Cristalli;Alessandra Eleuteri;Sauro Vittori;Rosaria Volpini

  169
  Citations

• Adenosine A1 receptor-mediated activation of phospholipase C in cultured astrocytes depends on the level of receptor expression

  Knut Biber;KN Klotz;M Berger;PJ GebickeHarter

  158
  Citations

• Photoaffinity labeling of A1-adenosine receptors.

  K N Klotz;G Cristalli;M Grifantini;S Vittori

  141
  Citations

• N(6)-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting point for searching A(2B) ligands.

  Rosaria Volpini;Stefano Costanzi;Catia Lambertucci;Sara Taffi

  134
  Citations

• Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonists.

  Pier Giovanni Baraldi;Barbara Cacciari;Stefano Moro;Giampiero Spalluto

  123
  Citations

• Synthesis of new delta 2-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic receptor antagonists.

  Paola Conti;Clelia Dallanoce;Marco De Amici;Carlo De Micheli

  122
  Citations

• [3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors.

  Stefania Gessi;Katia Varani;Stefania Merighi;K. N. Klotz

  27
  Citations