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Chemistry

D-Index
73
Citations
17191
World Ranking
5035
National Ranking
138

Overview

Eugenio Uriarte is affiliated with the University of Santiago de Compostela in Spain, focusing primarily on research within the fields of Medicine and Chemistry. Their work also spans several subfields including Organic Chemistry, Pharmacology, Molecular Biology, Computational Theory and Mathematics, and Materials Chemistry.

Uriarte's recent scientific contributions include a variety of papers showcasing a focus on chemical and pharmacological studies, especially related to bioactive compounds and drug discovery. Notable recent publications include:

  • Trending Topics on Coumarin and Its Derivatives in 2020 (2021, Molecules)
  • In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease (2021, Frontiers in Chemistry)
  • Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors (2021, Bioorganic Chemistry)
  • Looking for new xanthine oxidase inhibitors: 3-Phenylcoumarins versus 2-phenylbenzofurans (2020, International Journal of Biological Macromolecules)
  • Coumarin-Rasagiline Hybrids as Potent and Selective hMAO-B Inhibitors, Antioxidants, and Neuroprotective Agents (2020, ChemMedChem)

The main topics within Uriarte's research encompass areas such as:

  • Cholinesterase and Neurodegenerative Diseases
  • Synthesis and Biological Evaluation
  • Computational Drug Discovery Methods
  • Click Chemistry and Applications
  • Synthesis and biological activity
  • Pharmacological Effects of Natural Compounds
  • Gout, Hyperuricemia, Uric Acid

Frequent coauthors in their publications include María João Matos, Fernanda Borges, Dolores Viña, Lourdes Santana, and Benedetta Era, indicating collaborative research efforts within overlapping chemical and pharmacological disciplines.

Uriarte has published extensively in several scientific journals, with repeated contributions to the following venues:

  • Molecules
  • ChemMedChem
  • Bioorganic Chemistry
  • European Journal of Medicinal Chemistry
  • Arabian Journal of Chemistry

The scope of Uriarte's work integrates computational approaches and experimental synthesis to address challenges in drug discovery and medicinal chemistry. Their research includes the design of inhibitors for enzymes such as monoamine oxidase B and xanthine oxidase, along with studies involving coumarin derivatives in various biomedical contexts.

Best Publications

  • Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity.

    F. Borges;F. Roleira;N. Milhazes;L. Santana

  • Chromone: A Valid Scaffold in Medicinal Chemistry

    Alexandra Gaspar;Alexandra Gaspar;Maria João Matos;Maria João Matos;Jorge Garrido;Jorge Garrido;Eugenio Uriarte

  • Recent advances on the role of topological indices in drug discovery research.

    Ernesto Estrada;Eugenio Uriarte

  • Medicinal chemistry and bioinformatics--current trends in drugs discovery with networks topological indices.

    Humberto Gonzalez-Diaz;Santiago Vilar;Lourdes Santana;Eugenio Uriarte

  • Hesperidin as a Neuroprotective Agent: A Review of Animal and Clinical Evidence

    Marziyeh Hajialyani;Mohammad Hosein Farzaei;Javier Echeverría;Seyed Mohammad Nabavi

  • Proteomics, networks and connectivity indices.

    Humberto González-Díaz;Yenny González-Díaz;Lourdes Santana;Florencio M. Ubeira

  • Similarity-based modeling in large-scale prediction of drug-drug interactions

    Santiago Vilar;Eugenio Uriarte;Lourdes Santana;Tal Lorberbaum

  • Drug—drug interaction through molecular structure similarity analysis

    Santiago Vilar;Santiago Vilar;Rave Harpaz;Eugenio Uriarte;Lourdes Santana

  • Effects of cis-resveratrol on inflammatory murine macrophages: antioxidant activity and down-regulation of inflammatory genes.

    José Leiro;Ezequiel Álvarez;Juan A. Arranz;Reyes Laguna

  • Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity.

    L. Santana;E. Uriarte;F. Roleira;N. Milhazes

  • Coumarins — An Important Class of Phytochemicals

    Maria João Matos;Lourdes Santana;Eugenio Uriarte;Orlando A.Abreu

  • A Novel Approach for the Virtual Screening and Rational Design of Anticancer Compounds

    E Estrada;E Uriarte;A Montero;M Teijeira

  • Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin-resveratrol hybrids.

    Santiago Vilar;Elías Quezada;Lourdes Santana;Eugenio Uriarte

  • A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins.

    Lourdes Santana;Eugenio Uriarte;Humberto González-Díaz;Giuseppe Zagotto

  • Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors.

    Maria J Matos;Carmen Terán;Yunierkis Pérez-Castillo;Eugenio Uriarte

  • Potential pharmacological uses of chalcones: a patent review (from June 2011 – 2014)

    Maria João Matos;Saleta Vazquez-Rodriguez;Eugenio Uriarte;Lourdes Santana

  • Coumarin as Attractive Casein Kinase 2 (CK2) Inhibitor Scaffold: An Integrate Approach To Elucidate the Putative Binding Motif and Explain Structure–Activity Relationships

    Adriana Chilin;Roberto Battistutta;Andrea Bortolato;Giorgio Cozza

  • A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors.

    Maria Joao Matos;Dolores Viña;Elias Quezada;Carmen Picciau

  • Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.

    Alexandra Gaspar;Tiago Silva;Matilde Yáñez;Dolores Vina

  • Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

    Lourdes Santana;Humberto González-Díaz;Elías Quezada;Eugenio Uriarte

Frequent Co-Authors

Lourdes Santana
Lourdes Santana University of Santiago de Compostela
Maria João Matos
Maria João Matos University of Santiago de Compostela
Fernanda Borges
Fernanda Borges University of Porto
Humberto González-Díaz
Humberto González-Díaz University of the Basque Country
Ernesto Estrada
Ernesto Estrada Institute for Cross-Disciplinary Physics and Complex Systems
Karl-Norbert Klotz
Karl-Norbert Klotz University of Würzburg
Stefano Alcaro
Stefano Alcaro Magna Graecia University
George Hripcsak
George Hripcsak Columbia University
Francesco Ortuso
Francesco Ortuso Magna Graecia University
Florencio M. Ubeira
Florencio M. Ubeira University of Santiago de Compostela

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