Francesco Ortuso

Overview

Best Publications

• Chalcones: a valid scaffold for monoamine oxidases inhibitors.

  Franco Chimenti;Rossella Fioravanti;Adriana Bolasco;Paola Chimenti

  256
  Citations

• Synthesis, Molecular Modeling, and Selective Inhibitory Activity against Human Monoamine Oxidases of 3-Carboxamido-7-Substituted Coumarins†

  Franco Chimenti;Daniela Secci;Adriana Bolasco;Paola Chimenti

  189
  Citations

• Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors

  Rossella Fioravanti;Adriana Bolasco;Fedele Manna;Francesca Rossi

  164
  Citations

• Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)- pyrazole derivatives.

  Franco Chimenti;Elias Maccioni;Daniela Secci;Adriana Bolasco

  162
  Citations

• Quercetin as the active principle of Hypericum hircinum exerts a selective inhibitory activity against MAO-A: Extraction, biological analysis, and computational study

  Franco Chimenti;Filippo Cottiglia;Leonardo Bonsignore;Laura Casu

  161
  Citations

• Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.

  Alexandra Gaspar;Tiago Silva;Matilde Yáñez;Dolores Vina

  158
  Citations

• Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study

  Franco Chimenti;Daniela Secci;Adriana Bolasco;Paola Chimenti

  126
  Citations

• Synthesis, Biological Evaluation, and Molecular Modeling of Oleuropein and Its Semisynthetic Derivatives as Cyclooxygenase Inhibitors

  Antonio Procopio;Stefano Alcaro;Monica Nardi;Manuela Oliverio

  124
  Citations

• A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.

  Franco Chimenti;Rossella Fioravanti;Adriana Bolasco;Paola Chimenti

  123
  Citations

• Selective inhibitory activity against MAO and molecular modeling studies of 2-thiazolylhydrazone derivatives.

  Franco Chimenti;Elias Maccioni;Daniela Secci;Adriana Bolasco

  122
  Citations

• GBPM: GRID-based pharmacophore model: concept and application studies to protein--protein recognition

  Francesco Ortuso;Thierry Langer;Stefano Alcaro

  122
  Citations

• Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations

  Federica Moraca;Jussara Amato;Francesco Ortuso;Anna Artese

  121
  Citations

• Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives

  Daniela Secci;Simone Carradori;Adriana Bolasco;Paola Chimenti

  120
  Citations

• Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones.

  Franco Chimenti;Elias Maccioni;Daniela Secci;Adriana Bolasco

  110
  Citations

• Homoisoflavonoids: natural scaffolds with potent and selective monoamine oxidase-B inhibition properties.

  Nicoletta Desideri;Adriana Bolasco;Rossella Fioravanti;Luca Proietti Monaco

  106
  Citations

• Modeling and biological evaluation of 3,3′-(1,2-ethanediyl)bis[2-(4-methoxyphenyl)-thiazolidin-4-one], a new synthetic cyclooxygenase-2 inhibitor

  Rosaria Ottaná;Emanuela Mazzon;Laura Dugo;Francesca Monforte

  102
  Citations

• Investigations on the 2-thiazolylhydrazyne scaffold: Synthesis and molecular modeling of selective human monoamine oxidase inhibitors

  Franco Chimenti;Adriana Bolasco;Daniela Secci;Paola Chimenti

  100
  Citations

• Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors

  Joana Reis;Fernando Cagide;Daniel Chavarria;Tiago Silva

  97
  Citations

• Monoamine Oxidase Isoform-Dependent Tautomeric Influence in the Recognition of 3,5-Diaryl Pyrazole Inhibitors

  Franco Chimenti;Rossella Fioravanti;Adriana Bolasco;Fedele Manna

  94
  Citations

• Further studies on the interaction of the 5-hydroxytryptamine3 (5-HT3) receptor with arylpiperazine ligands. development of a new 5-HT3 receptor ligand showing potent acetylcholinesterase inhibitory properties.

  Andrea Cappelli;Andrea Gallelli;Monica Manini;Maurizio Anzini

  90
  Citations

• SGK1, the New Player in the Game of Resistance: Chemo-Radio Molecular Target and Strategy for Inhibition

  Cristina Talarico;Vincenzo Dattilo;Lucia D'Antona;Miranda Menniti

  85
  Citations