World's Best Scientists 2026 revealed!
Jean-Louis Mergny

Jean-Louis Mergny

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Molecular Biology
France
2025
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Genetics and Molecular Biology
France
2024

D-Index & Metrics

Molecular Biology

D-Index
97
Citations
42219
World Ranking
587
National Ranking
14

Jean-Louis Mergny publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Jean-Louis Mergny sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 391 publications — 90th percentile

90% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Jean-Louis Mergny D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Jean-Louis Mergny sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 97 D-Index — 81st percentile

81% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Research.com Recognitions

  • 2025 - Research.com Molecular Biology in France Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award
  • 2023 - Research.com Molecular Biology in France Leader Award
  • 2019 - Member of Academia Europaea

Overview

Jean-Louis Mergny is affiliated with Inserm in France and works extensively in the field of Biochemistry, Genetics, and Molecular Biology. Their research focuses primarily on Molecular Biology, with additional work spanning Ecology, Plant Science, Materials Chemistry, and Organic Chemistry.

The scientist's main topics of research include:

  • DNA and Nucleic Acid Chemistry
  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • RNA and protein synthesis mechanisms
  • Bacteriophages and microbial interactions
  • Genomics and Chromatin Dynamics
  • Plant Virus Research Studies

Jean-Louis Mergny has contributed to a significant number of publications in various academic venues. The most frequent publication venues include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature (29 publications)
  • Nucleic Acids Research (15 publications)
  • Biochimie (10 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • Angewandte Chemie International Edition (5 publications)

The scientist has collaborated frequently with other researchers, including:

  • Jun Zhou (26 collaborations)
  • Huangxian Ju (21 collaborations)
  • Anne Cucchiarini (20 collaborations)
  • Václav Brázda (19 collaborations)
  • Mingpan Cheng (18 collaborations)

Some of the recent papers authored or co-authored by Jean-Louis Mergny include:

  • "G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies," 2020, Trends in Molecular Medicine
  • "Unlocking G-Quadruplexes as Antiviral Targets," 2021, Pharmacological Reviews
  • "G-quadruplex ligands in cancer therapy: Progress, challenges, and clinical perspectives," 2024, Life Sciences
  • "SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction," 2021, Nucleic Acids Research
  • "Thermal and pH Stabilities of i-DNA: Confronting in vitro Experiments with Models and In-Cell NMR Data," 2021, Angewandte Chemie International Edition

In 2019, Jean-Louis Mergny was recognized as a Member of Academia Europaea, reflecting their involvement in the wider European scientific community.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Analysis of thermal melting curves

    Jean-Louis Mergny;Laurent Lacroix

  • Following G-quartet formation by UV-spectroscopy

    Jean-Louis Mergny;Anh-Tuan Phan;Laurent Lacroix

  • Targeting telomeres and telomerase

    Anne De Cian;Laurent Lacroix;Laurent Lacroix;Céline Douarre;Nassima Temime-Smaali

  • Re-evaluation of G-quadruplex propensity with G4Hunter

    Amina Bedrat;Laurent Lacroix;Jean-Louis Mergny

  • Human telomeric DNA: G‐quadruplex, i‐motif and Watson–Crick double helix

    Anh Tuân Phan;Jean‐Louis Mergny

  • Thermal difference spectra: a specific signature for nucleic acid structures

    Jean-Louis Mergny;Jing Li;Laurent Lacroix;Samir Amrane

  • Natural and pharmacological regulation of telomerase

    Jean-Louis Mergny;Jean-François Riou;Patrick Mailliet;Marie-Paule Teulade-Fichou

  • Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands.

    J. F. Riou;L. Guittat;P. Mailliet;A. Laoui

  • G-quadruplex DNA: A target for drug design

    Jean-Louis Mergny;Claude Hélène

  • Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

    Anne De Cian;Elsa Delemos;Jean-Louis Mergny;Marie-Paule Teulade-Fichou

  • How long is too long? Effects of loop size on G-quadruplex stability

    Aurore Guédin;Julien Gros;Patrizia Alberti;Jean-Louis Mergny

  • DNA duplex–quadruplex exchange as the basis for a nanomolecular machine

    Patrizia Alberti;Jean-Louis Mergny

  • Fluorescence-based melting assays for studying quadruplex ligands

    Anne De Cian;Lionel Guittat;Markus Kaiser;Barbara Saccà

  • G-quadruplexes and helicases.

    Oscar Mendoza;Anne Bourdoncle;Anne Bourdoncle;Jean-Baptiste Boulé;Jean-Baptiste Boulé;Robert M. Brosh

  • Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay.

    Jean-Louis Mergny;Laurent Lacroix;Marie-Paule Teulade-Fichou;Candide Hounsou

  • Thioflavin T as a fluorescence light-up probe for G4 formation

    Amandine Renaud de la Faverie;Aurore Guédin;Amina Bedrat;Liliya A. Yatsunyk

  • The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

    Cyril Ribeyre;Judith Lopes;Jean Baptiste Boulé;Jean Baptiste Boulé;Aurèle Piazza

  • Intramolecular Folding of Pyrimidine Oligodeoxynucleotides into an i-DNA Motif

    Jean-Louis Mergny;Laurent Lacroix;Xiaogang Han;Jean-Louis Leroy

  • Triple Helix-Specific Ligands

    J. L. Mergny;G. Duval-Valentin;C. H. Nguyen;L. Perrouault

Frequent Co-Authors

Marie-Paule Teulade-Fichou
Marie-Paule Teulade-Fichou University of Paris-Saclay
Jean-François Riou
Jean-François Riou French National Museum of Natural History
Claude Hélène
Claude Hélène Grenoble Alpes University
Valérie Gabelica
Valérie Gabelica University of Bordeaux
João A. Queiroz
João A. Queiroz University of Beira Interior
Dik-Lung Ma
Dik-Lung Ma Hong Kong Baptist University
Chung-Hang Leung
Chung-Hang Leung University of Macau
Huangxian Ju
Huangxian Ju Nanjing University
Jiří Šponer
Jiří Šponer Masaryk University
Jean-Marie Lehn
Jean-Marie Lehn University of Strasbourg

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