Zhi-Shu Huang

Overview

Best Publications

• G-Quadruplexes: Targets in Anticancer Drug Design

  Tian Miao Ou;Yu Jing Lu;Jia Heng Tan;Zhi Shu Huang

  669
  Citations

• Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives

  Tian-Miao Ou;Yu-Jing Lu;Chi Zhang;Zhi-Shu Huang

  360
  Citations

• α-Glucosidase inhibition of natural curcuminoids and curcumin analogs

  Zhi-yun Du;Rong-rong Liu;Wei-yan Shao;Xue-pu Mao

  282
  Citations

• Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.

  Jin Lin Zhou;Yu Jing Lu;Tian Miao Ou;Jun Min Zhou

  214
  Citations

• Tracking the Dynamic Folding and Unfolding of RNA G-Quadruplexes in Live Cells.

  Xiu-Cai Chen;Shuo-Bin Chen;Jing Dai;Jia-Hao Yuan

  195
  Citations

• From Indoles to Carbazoles: Tandem Cp*Rh(III)-Catalyzed C–H Activation/Brønsted Acid-Catalyzed Cyclization Reactions

  Jia-Qiang Wu;Zhen Yang;Shang-Shi Zhang;Chun-Yong Jiang

  191
  Citations

• 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.

  Yu Jing Lu;Tian Miao Ou;Jia Heng Tan;Jin Qiang Hou

  178
  Citations

• 9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA

  Wan-Jin Zhang;Tian-Miao Ou;Yu-Jing Lu;Ying-Yu Huang

  169
  Citations

• 9-N-Substituted berberine derivatives: Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc

  Yan Ma;Tian-Miao Ou;Jin-Qiang Hou;Yu-Jing Lu

  153
  Citations

• Rhodium(iii)-catalyzed C–H/C–C activation sequence: vinylcyclopropanes as versatile synthons in direct C–H allylation reactions

  Jia-Qiang Wu;Zhi-Ping Qiu;Shang-Shi Zhang;Jing-Gong Liu

  149
  Citations

• Visualization of NRAS RNA G-Quadruplex Structures in Cells with an Engineered Fluorogenic Hybridization Probe

  Shuo-Bin Chen;Ming-Hao Hu;Guo-Cai Liu;Jin Wang

  140
  Citations

• Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole.

  Ming-Hao Hu;Shuo-Bin Chen;Bo Wang;Tian-Miao Ou

  137
  Citations

• Inhibition of Cell Proliferation by Quindoline Derivative (SYUIQ-05) through its Preferential Interaction with c-myc Promoter G-Quadruplex

  Tian-Miao Ou;Jing Lin;Yu-Jing Lu;Jin-Qiang Hou

  131
  Citations

• Conformation Selective Antibody Enables Genome Profiling and Leads to Discovery of Parallel G-Quadruplex in Human Telomeres

  Hui-Yun Liu;Qi Zhao;Tian-Peng Zhang;Yue Wu

  123
  Citations

• Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex.

  Ming-Hao Hu;Ming-Hao Hu;Yu-Qing Wang;Ze-Yi Yu;Lu-Ni Hu

  118
  Citations

• Turning off Transcription of the bcl-2 Gene by Stabilizing the bcl-2 Promoter Quadruplex with Quindoline Derivatives

  Xiao-Dong Wang;Tian-Miao Ou;Yu-Jing Lu;Zeng Li

  117
  Citations

• Synthesis and biological evaluation of functionalized coumarins as acetylcholinesterase inhibitors.

  Qiong Shen;Quan Peng;Jialiang Shao;Xufeng Liu

  117
  Citations

• Cp*Rh(III) and Cp*Ir(III)-catalysed redox-neutral C–H arylation with quinone diazides: quick and facile synthesis of arylated phenols

  Shang-Shi Zhang;Chun-Yong Jiang;Jia-Qiang Wu;Xu-Ge Liu

  117
  Citations

• Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer’s disease

  Shang-Ying Chen;Yuan Chen;Yan-Ping Li;Shu-Han Chen

  114
  Citations

• Akt/Ezrin Tyr353/NF-κB pathway regulates EGF-induced EMT and metastasis in tongue squamous cell carcinoma.

  Y Wang;Z Lin;L Sun;S Fan

  112
  Citations

• Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase.

  Huang Tang;Yong-Biao Wei;Chi Zhang;Fang-Xian Ning

  111
  Citations