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D-Index & Metrics

Chemistry

D-Index
47
Citations
10780
World Ranking
15496
National Ranking
3913

Overview

Danzhou Yang is affiliated with Purdue University West Lafayette in the United States and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their publication record includes 85 works primarily centered on molecular biology, with additional research in organic chemistry, ecology, pulmonary and respiratory medicine, and epidemiology.

Their research focuses on areas such as DNA and nucleic acid chemistry, advanced biosensing and bioanalysis techniques, RNA interference and gene delivery, mechanisms of RNA and protein synthesis, RNA modifications in cancer, cancer therapeutics and mechanisms, and bacteriophage and microbial interactions.

Frequent coauthors who have collaborated with Yang include Jonathan Dickerhoff, Guanhui Wu, Kai-Bo Wang, Luying Chen, and Yichen Han, reflecting productive research partnerships.

Their recent notable publications include:

  • DNA G-Quadruplex in Human Telomeres and Oncogene Promoters: Structures, Functions, and Small Molecule Targeting (2022) in Accounts of Chemical Research
  • Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes (2021) in Nucleic Acids Research
  • Custom DNA Microarrays Reveal Diverse Binding Preferences of Proteins and Small Molecules to Thousands of G-Quadruplexes (2020) in ACS Chemical Biology
  • PDGFR-β Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs (2020) in Journal of the American Chemical Society
  • RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes (2021) in Gut

Yang's work has been published frequently in several scientific venues, including:

  • Cancer Research
  • Journal of the American Chemical Society
  • Nucleic Acids Research
  • Journal of Medicinal Chemistry
  • Molecules

Best Publications

  • Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution

    Attila Ambrus;Ding Chen;Jixun Dai;Tiffanie Bialis

  • Solution Structure of the Biologically Relevant G-Quadruplex Element in the Human c-MYC Promoter. Implications for G-Quadruplex Stabilization†

    Attila Ambrus;Ding Chen;Jixun Dai;Roger A. Jones

  • Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence

    Jixun Dai;Megan Carver;Chandanamali Punchihewa;Roger A. C. Jones

  • An Intramolecular G-Quadruplex Structure with Mixed Parallel/Antiparallel G-Strands Formed in the Human BCL-2 Promoter Region in Solution

    Jixun Dai;Thomas S. Dexheimer;Ding Chen;Megan Carver

  • Polymorphism of human telomeric quadruplex structures

    Jixun Dai;Megan Carver;Danzhou Yang

  • Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation

    Jixun Dai;Chandanamali Punchihewa;Attila Ambrus;Ding Chen

  • NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.

    Jixun Dai;Ding Chen;Roger A. C. Jones;Laurence H. Hurley

  • Solution Structure of a 2:1 Quindoline-c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design.

    Jixun Dai;Megan Carver;Laurence H. Hurley;Danzhou Yang

  • Structural insights into G-quadruplexes: towards new anticancer drugs

    Danzhou Yang;Keika Okamoto

  • c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability.

    Raveendra I. Mathad;Emmanuel Hatzakis;Jixun Dai;Danzhou Yang

  • Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis.

    Danzhou Yang;S. S. G. E. Van Boom;J. Reedijk;J. H. Van Boom

  • The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure

    Samantha Kendrick;Hyun Jin Kang;Mohammad P. Alam;Manikandadas M. Madathil

  • Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures

    Zhenjiang Zhang;Jixun Dai;Elizabeth Veliath;Roger A. C. Jones

  • Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

    Danzhou Yang;Laurence H Hurley

  • Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression

    Christine E. Kaiser;Natalie A. Van Ert;Prashansa Agrawal;Reena Chawla

  • The major G-quadruplex formed in the human BCL-2 proximal promoter adopts a parallel structure with a 13-nt loop in K+ solution.

    Prashansa Agrawal;Clement Lin;Raveendra I. Mathad;Megan Carver

  • Solution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexes.

    Prashansa Agrawal;Emmanuel Hatzakis;Kexiao Guo;Megan Carver

  • DNA G-Quadruplex in Human Telomeres and Oncogene Promoters: Structures, Functions, and Small Molecule Targeting.

    Unknown

  • Drug targeting of the c-MYC promoter to repress gene expression via a G-quadruplex silencer element.

    Laurence H. Hurley;Daniel D. Von Hoff;Adam Siddiqui-Jain;Danzhou Yang

  • A New G-Quadruplex with Hairpin Loop Immediately Upstream of the Human BCL2 P1 Promoter Modulates Transcription

    Buket Onel;Megan Carver;Guanhui Wu;Daria Timonina

  • Sequence, Stability, and Structure of G‐Quadruplexes and Their Interactions with Drugs

    Yuwei Chen;Danzhou Yang

Frequent Co-Authors

Laurence H. Hurley
Laurence H. Hurley University of Arizona
Andrew H.-J. Wang
Andrew H.-J. Wang Academia Sinica
Roger A. Jones
Roger A. Jones Rutgers, The State University of New Jersey
Jan Reedijk
Jan Reedijk Leiden University
J. H. Van Boom
J. H. Van Boom Leiden University
Zong-Wan Mao
Zong-Wan Mao Sun Yat-sen University
Charles Vinson
Charles Vinson National Institutes of Health
Nicholas Farrell
Nicholas Farrell Virginia Commonwealth University
Mark Cushman
Mark Cushman Purdue University West Lafayette

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