World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
99
Citations
37626
World Ranking
1582
National Ranking
887

Chemistry

D-Index
97
Citations
36696
World Ranking
1457
National Ranking
560

Laurence H. Hurley publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Laurence H. Hurley sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 332 publications — 70th percentile

70% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Laurence H. Hurley D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Laurence H. Hurley sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 97 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Laurence H. Hurley is affiliated with the University of Arizona in the United States. Their research primarily spans the broad field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology as the dominant subfield among their work. Other subfields include Cell Biology, Epidemiology, Physiology, and Biotechnology.

The scientist's work covers various specialized topics, including:

  • DNA and Nucleic Acid Chemistry
  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • RNA and protein synthesis mechanisms
  • Cancer therapeutics and mechanisms
  • Heme Oxygenase-1 and Carbon Monoxide
  • Hemoglobin structure and function

Laurence H. Hurley has contributed to multiple publications in different scientific venues. Frequent publication venues include:

  • Bioorganic & Medicinal Chemistry Letters
  • Oncotarget
  • Journal of the American Chemical Society
  • Science
  • Cell Reports

Selected recent papers authored or coauthored by Laurence H. Hurley include:

  • "DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells," 2020, Journal of the American Chemical Society
  • "A first-in-class clinical G-quadruplex-targeting drug. The bench-to-bedside translation of the fluoroquinolone QQ58 to CX-5461 (Pidnarulex)," 2022, Bioorganic & Medicinal Chemistry Letters
  • "Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases," 2020, Cell Reports
  • "The role of G-Quadruplex DNA in Paraspeckle formation in cancer," 2021, Biochimie
  • "A synthetic lethal approach to drug targeting of G-quadruplexes based on CX-5461," 2023, Bioorganic & Medicinal Chemistry Letters

Frequent coauthors working with Laurence H. Hurley include:

  • Vijay Gokhale
  • Cameron W. Evans
  • K. Swaminathan Iyer
  • Nicole M. Smith
  • Hong Xu

Best Publications

  • Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.

    Adam Siddiqui-Jain;Cory L. Grand;David J. Bearss;Laurence H. Hurley

  • Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

    Shankar Balasubramanian;Laurence H. Hurley;Stephen Neidle

  • DNA and its associated processes as targets for cancer therapy

    Laurence H. Hurley

  • Inhibition of human telomerase by a G-quadruplex-interactive compound.

    Daekyu Sun;Brian Thompson;Brian E. Cathers;Miguel Salazar

  • Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex.

    Mu Yong Kim;Hariprasad Vankayalapati;Kazuo Shin-Ya;Konstanty Wierzba

  • G-quadruplex DNA: a potential target for anti-cancer drug design

    Haiyong Han;Laurence H Hurley

  • Cationic Porphyrins as Telomerase Inhibitors: the Interaction of Tetra-(N-methyl-4-pyridyl)porphine with Quadruplex DNA

    Richard T. Wheelhouse;Daekyu Sun;Haiyong Han;and Frank Xiaoguang Han

  • Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

    Yong Qin;Laurence H. Hurley

  • Making sense of G-quadruplex and i-motif functions in oncogene promoters

    Tracy A. Brooks;Samantha Kendrick;Laurence Hurley

  • Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents

    Daekyu Sun;Kexiao Guo;Jadrian J. Rusche;Laurence H. Hurley

  • Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells.

    E Izbicka;R T Wheelhouse;R T Wheelhouse;E Raymond;K K Davidson

  • The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression.

    Daekyu Sun;Laurence H. Hurley

  • NMR-Based Model of a Telomerase-Inhibiting Compound Bound to G-Quadruplex DNA†

    Oleg Yu Fedoroff;Miguel Salazar;Haiyong Han;Violetta V. Chemeris

  • The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo.

    Cory L Grand;Haiyong Han;Rubén M Muñoz;Steve Weitman

  • Interactions of TMPyP4 and TMPyP2 with Quadruplex DNA. Structural Basis for the Differential Effects on Telomerase Inhibition

    Frank Xiaoguang Han;Richard T. Wheelhouse;Laurence H. Hurley

  • The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4.

    Jeyaprakashnarayanan Seenisamy;Evonne M. Rezler;Tiffanie J. Powell;Denise Tye

  • Deconvoluting the Structural and Drug-Recognition Complexity of the G-Quadruplex-Forming Region Upstream of the bcl-2 P1 Promoter

    Thomas S. Dexheimer;Daekyu Sun;Laurence H. Hurley

  • Selective interactions of cationic porphyrins with G-quadruplex structures.

    Haiyong Han;David R. Langley;and Anupama Rangan;Laurence H. Hurley

  • NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.

    Jixun Dai;Ding Chen;Roger A. C. Jones;Laurence H. Hurley

  • Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure.

    Evonne M. Rezler;Jeyaprakashnarayanan Seenisamy;Sridevi Bashyam;Mu Yong Kim

Frequent Co-Authors

Danzhou Yang
Danzhou Yang Purdue University West Lafayette
David E. Thurston
David E. Thurston King's College London
Heinz G. Floss
Heinz G. Floss University of Washington
Stephen Neidle
Stephen Neidle University College London
Daniel D. Von Hoff
Daniel D. Von Hoff Translational Genomics Research Institute
Michael E. Berens
Michael E. Berens Translational Genomics Research Institute
Nikhil C. Munshi
Nikhil C. Munshi Harvard University
Lisa M. Rimsza
Lisa M. Rimsza Mayo Clinic
Sidney M. Hecht
Sidney M. Hecht Arizona State University
Jeffrey M. Trent
Jeffrey M. Trent Translational Genomics Research Institute

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