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Laurence H. Hurley

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Chemistry 97 1457 1293 560 459 332 36696
Biology and Biochemistry 99 1581 1426 886 783 350 37626

Laurence H. Hurley publications per year

The chart shows the history of publications by Laurence H. Hurley between 1969 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Laurence H. Hurley published across 57 years, from 1969 to 2025, averaging 6.7 papers a year. Output peaked at 19 publications in 1999. 3 of the 381 publications appeared in the last two years.

No. of publications
5 10 15
Bar chart. Horizontal axis: year, 1969 to 2025. Vertical axis: number of publications, 0 to 19. Peak 19 publications in 1999. 1969: 2 publications 1970: 2 publications 1971: 1 publication 1972: 0 publications 1973: 0 publications 1974: 2 publications 1975: 2 publications 1976: 4 publications 1977: 3 publications 1978: 2 publications 1979: 11 publications 1980: 6 publications 1981: 8 publications 1982: 3 publications 1983: 2 publications 1984: 5 publications 1985: 4 publications 1986: 8 publications 1987: 4 publications 1988: 7 publications 1989: 1 publication 1990: 5 publications 1991: 5 publications 1992: 9 publications 1993: 10 publications 1994: 6 publications 1995: 10 publications 1996: 14 publications 1997: 11 publications 1998: 16 publications 1999: 19 publications 2000: 8 publications 2001: 10 publications 2002: 11 publications 2003: 11 publications 2004: 13 publications 2005: 13 publications 2006: 8 publications 2007: 8 publications 2008: 8 publications 2009: 13 publications 2010: 12 publications 2011: 10 publications 2012: 5 publications 2013: 2 publications 2014: 3 publications 2015: 3 publications 2016: 11 publications 2017: 11 publications 2018: 6 publications 2019: 5 publications 2020: 7 publications 2021: 1 publication 2022: 2 publications 2023: 15 publications 2024: 1 publication 2025: 2 publications
1969 2025

381 publications in total across all disciplines

View publications per year as a table
Laurence H. Hurley: publications per year, 1969 to 2025
Year Publications
1969 2
1970 2
1971 1
1972 0
1973 0
1974 2
1975 2
1976 4
1977 3
1978 2
1979 11
1980 6
1981 8
1982 3
1983 2
1984 5
1985 4
1986 8
1987 4
1988 7
1989 1
1990 5
1991 5
1992 9
1993 10
1994 6
1995 10
1996 14
1997 11
1998 16
1999 19
2000 8
2001 10
2002 11
2003 11
2004 13
2005 13
2006 8
2007 8
2008 8
2009 13
2010 12
2011 10
2012 5
2013 2
2014 3
2015 3
2016 11
2017 11
2018 6
2019 5
2020 7
2021 1
2022 2
2023 15
2024 1
2025 2
Total 381
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Laurence H. Hurley publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Laurence H. Hurley sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 321–340 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 332 publications — 70th percentile

70% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623
121–140 918
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979
281–300 939
301–320 764
321–340 643 332
341–360 628
361–380 522
381–400 459
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
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Laurence H. Hurley D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Laurence H. Hurley sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 96–97 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 97 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051
58–59 930
60–61 882
62–63 834
64–65 731
66–67 775
68–69 683
70–71 646
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235
90–91 185
92–93 192
94–95 155
96–97 163 97
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
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Overview

Laurence H. Hurley is affiliated with the University of Arizona in the United States. Their research primarily spans the broad field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology as the dominant subfield among their work. Other subfields include Cell Biology, Epidemiology, Physiology, and Biotechnology.

The scientist's work covers various specialized topics, including:

  • DNA and Nucleic Acid Chemistry
  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • RNA and protein synthesis mechanisms
  • Cancer therapeutics and mechanisms
  • Heme Oxygenase-1 and Carbon Monoxide
  • Hemoglobin structure and function

Laurence H. Hurley has contributed to multiple publications in different scientific venues. Frequent publication venues include:

  • Bioorganic & Medicinal Chemistry Letters
  • Oncotarget
  • Journal of the American Chemical Society
  • Science
  • Cell Reports

Selected recent papers authored or coauthored by Laurence H. Hurley include:

  • "DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells," 2020, Journal of the American Chemical Society
  • "A first-in-class clinical G-quadruplex-targeting drug. The bench-to-bedside translation of the fluoroquinolone QQ58 to CX-5461 (Pidnarulex)," 2022, Bioorganic & Medicinal Chemistry Letters
  • "Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases," 2020, Cell Reports
  • "The role of G-Quadruplex DNA in Paraspeckle formation in cancer," 2021, Biochimie
  • "A synthetic lethal approach to drug targeting of G-quadruplexes based on CX-5461," 2023, Bioorganic & Medicinal Chemistry Letters

Frequent coauthors working with Laurence H. Hurley include:

  • Vijay Gokhale
  • Cameron W. Evans
  • K. Swaminathan Iyer
  • Nicole M. Smith
  • Hong Xu

Best Publications

  • Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.

    Adam Siddiqui-Jain;Cory L. Grand;David J. Bearss;Laurence H. Hurley

  • Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

    Shankar Balasubramanian;Laurence H. Hurley;Stephen Neidle

  • DNA and its associated processes as targets for cancer therapy

    Laurence H. Hurley

  • Inhibition of human telomerase by a G-quadruplex-interactive compound.

    Daekyu Sun;Brian Thompson;Brian E. Cathers;Miguel Salazar

  • Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex.

    Mu Yong Kim;Hariprasad Vankayalapati;Kazuo Shin-Ya;Konstanty Wierzba

  • G-quadruplex DNA: a potential target for anti-cancer drug design

    Haiyong Han;Laurence H Hurley

  • Cationic Porphyrins as Telomerase Inhibitors: the Interaction of Tetra-(N-methyl-4-pyridyl)porphine with Quadruplex DNA

    Richard T. Wheelhouse;Daekyu Sun;Haiyong Han;and Frank Xiaoguang Han

  • Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

    Yong Qin;Laurence H. Hurley

  • Making sense of G-quadruplex and i-motif functions in oncogene promoters

    Tracy A. Brooks;Samantha Kendrick;Laurence Hurley

  • Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents

    Daekyu Sun;Kexiao Guo;Jadrian J. Rusche;Laurence H. Hurley

  • Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells.

    E Izbicka;R T Wheelhouse;R T Wheelhouse;E Raymond;K K Davidson

  • The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression.

    Daekyu Sun;Laurence H. Hurley

  • NMR-Based Model of a Telomerase-Inhibiting Compound Bound to G-Quadruplex DNA†

    Oleg Yu Fedoroff;Miguel Salazar;Haiyong Han;Violetta V. Chemeris

  • The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo.

    Cory L Grand;Haiyong Han;Rubén M Muñoz;Steve Weitman

  • Interactions of TMPyP4 and TMPyP2 with Quadruplex DNA. Structural Basis for the Differential Effects on Telomerase Inhibition

    Frank Xiaoguang Han;Richard T. Wheelhouse;Laurence H. Hurley

  • The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4.

    Jeyaprakashnarayanan Seenisamy;Evonne M. Rezler;Tiffanie J. Powell;Denise Tye

  • Deconvoluting the Structural and Drug-Recognition Complexity of the G-Quadruplex-Forming Region Upstream of the bcl-2 P1 Promoter

    Thomas S. Dexheimer;Daekyu Sun;Laurence H. Hurley

  • Selective interactions of cationic porphyrins with G-quadruplex structures.

    Haiyong Han;David R. Langley;and Anupama Rangan;Laurence H. Hurley

  • NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.

    Jixun Dai;Ding Chen;Roger A. C. Jones;Laurence H. Hurley

  • Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure.

    Evonne M. Rezler;Jeyaprakashnarayanan Seenisamy;Sridevi Bashyam;Mu Yong Kim

Frequent Co-Authors

Danzhou Yang
Danzhou Yang Purdue University West Lafayette
David E. Thurston
David E. Thurston King's College London
Heinz G. Floss
Heinz G. Floss University of Washington
Stephen Neidle
Stephen Neidle University College London
Daniel D. Von Hoff
Daniel D. Von Hoff Translational Genomics Research Institute
Michael E. Berens
Michael E. Berens Translational Genomics Research Institute
Nikhil C. Munshi
Nikhil C. Munshi Harvard University
Lisa M. Rimsza
Lisa M. Rimsza Mayo Clinic
Sidney M. Hecht
Sidney M. Hecht Arizona State University
Jeffrey M. Trent
Jeffrey M. Trent Translational Genomics Research Institute

External Links

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Publications: 94

Marie-Paule Teulade-Fichou

Marie-Paule Teulade-Fichou

University of Paris-Saclay

Publications: 79

Zhi-Shu Huang

Zhi-Shu Huang

Sun Yat-sen University

Publications: 68

Anh Tuân Phan

Anh Tuân Phan

Nanyang Technological University

Publications: 68

Hiroshi Sugiyama

Hiroshi Sugiyama

Kyoto University

Publications: 67

Jia-Heng Tan

Jia-Heng Tan

Sun Yat-sen University

Publications: 61

Naoki Sugimoto

Naoki Sugimoto

Konan University

Publications: 60

Dale L. Boger

Dale L. Boger

Scripps Research Institute

Publications: 59

David E. Thurston

David E. Thurston

King's College London

Publications: 59

Yalin Tang

Yalin Tang

Chinese Academy of Sciences

Publications: 59

Tian-Miao Ou

Tian-Miao Ou

Sun Yat-sen University

Publications: 57

Xiang Zhou

Xiang Zhou

Wuhan University

Publications: 49

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Chinese Academy of Sciences

Publications: 46

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