What is he best known for?
The fields of study he is best known for:
Kazuo Shin-ya spends much of his time researching Telomestatin, Stereochemistry, Biochemistry, G-quadruplex and Telomere.
His Telomestatin research is multidisciplinary, relying on both Cancer research, Telomeric dna and Analytical chemistry.
His Stereochemistry study combines topics from a wide range of disciplines, such as Carboxylic acid, Biosynthesis, Polyketide and Pseudomonas.
His Biochemistry study frequently draws connections to adjacent fields such as Streptomyces.
His work deals with themes such as Selectivity, Intramolecular force, Ligand and Circular dichroism, which intersect with G-quadruplex.
Kazuo Shin-ya has included themes like Telomere-binding protein, Molecular biology, Telomere Recombination and DNA damage in his Telomere study.
His most cited work include:
- Telomestatin, a Novel Telomerase Inhibitor from Streptomyces anulatus (399 citations)
- Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex. (392 citations)
- FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability. (293 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Stereochemistry, Biochemistry, Streptomyces, Microbiology and Telomestatin.
The various areas that Kazuo Shin-ya examines in his Stereochemistry study include Derivative and Sponge.
His biological study spans a wide range of topics, including Cell culture and Cytotoxicity.
Telomestatin is the topic of his studies on Telomerase, G-quadruplex and Telomere.
His study in Telomere is interdisciplinary in nature, drawing from both Molecular biology and Cancer research.
As a part of the same scientific family, he mostly works in the field of Biosynthesis, focusing on Gene cluster and, on occasion, Polyketide.
He most often published in these fields:
- Stereochemistry (44.89%)
- Biochemistry (31.06%)
- Streptomyces (25.25%)
What were the highlights of his more recent work (between 2016-2021)?
- Heterologous expression (12.42%)
- Gene cluster (12.63%)
- Biosynthesis (11.22%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Heterologous expression, Gene cluster, Biosynthesis, Gene and Biochemistry.
Kazuo Shin-ya has researched Heterologous expression in several fields, including Streptomyces avermitilis, Bacterial artificial chromosome, Polyketide synthase, Cloning and Computational biology.
Many of his studies involve connections with topics such as Streptomyces and Gene cluster.
His Streptomyces research incorporates elements of Fermentation, Carbazole, Molecular chaperone GRP78, Stereochemistry and Cytotoxicity.
The concepts of his Stereochemistry study are interwoven with issues in Pikromycin, Ring, Biotransformation and Carboxylic acid.
The study incorporates disciplines such as Amino acid and Moiety in addition to Biosynthesis.
Between 2016 and 2021, his most popular works were:
- Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides. (52 citations)
- Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria. (31 citations)
- Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria. (31 citations)
In his most recent research, the most cited papers focused on:
Kazuo Shin-ya focuses on Heterologous expression, Gene cluster, Biosynthesis, Biochemistry and Gene.
The Biosynthesis study combines topics in areas such as Moiety, Stereochemistry, Nucleophilic addition and Aziridine.
Many of his studies on Biochemistry apply to Triple helix as well.
His Gene research is multidisciplinary, incorporating perspectives in Streptomyces avermitilis and Streptomyces.
His Streptomyces study incorporates themes from Hydrazone and Natural product.
Kazuo Shin-ya combines subjects such as Telomestatin and Cell biology with his study of Peptide.
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