Wen Liu

Overview

Best Publications

• Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

  Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers

  2194
  Citations

• Minimum Information about a Biosynthetic Gene cluster.

  Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  925
  Citations

• A genomics-guided approach for discovering and expressing cryptic metabolic pathways.

  Emmanuel Zazopoulos;Kexue Huang;Alfredo Staffa;Wen Liu

  415
  Citations

• Biosynthesis of the enediyne antitumor antibiotic C-1027.

  Wen Liu;Steven D. Christenson;Scott Standage;Ben Shen

  359
  Citations

• Thiopeptide Biosynthesis Featuring Ribosomally Synthesized Precursor Peptides and Conserved Posttranslational Modifications

  Rijing Liao;Lian Duan;Chun Lei;Haixue Pan

  227
  Citations

• Radical-mediated enzymatic methylation: a tale of two SAMS.

  Qi Zhang;Wilfred A. van der Donk;Wilfred A. van der Donk;Wen Liu

  223
  Citations

• Genetic Characterization of the Chlorothricin Gene Cluster as a Model for Spirotetronate Antibiotic Biosynthesis

  Xin-Ying Jia;Zhen-Hua Tian;Lei Shao;Lei Shao;Xu-Dong Qu

  193
  Citations

• Nosiheptide Biosynthesis Featuring a Unique Indole Side Ring Formation on the Characteristic Thiopeptide Framework

  Yi Yu;Lian Duan;Qi Zhang;Rijing Liao

  182
  Citations

• The Neocarzinostatin Biosynthetic Gene Cluster from Streptomyces carzinostaticus ATCC 15944 Involving Two Iterative Type I Polyketide Synthases

  Wen Liu;Koichi Nonaka;Liping Nie;Jian Zhang

  150
  Citations

• An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins.

  Zhenhua Tian;Peng Sun;Yan Yan;Zhuhua Wu

  148
  Citations

• Characterization of the saframycin a gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner

  Lei Li;Wei Deng;Jie Song;Wei Ding

  147
  Citations

• A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis.

  Steven D. Christenson;Wen Liu;Michael D. Toney;Ben Shen

  145
  Citations

• Radical-mediated enzymatic carbon chain fragmentation-recombination

  Qi Zhang;Yuxue Li;Dandan Chen;Yi Yu

  135
  Citations

• Cloning and Characterization of the Tetrocarcin A Gene Cluster from Micromonospora chalcea NRRL 11289 Reveals a Highly Conserved Strategy for Tetronate Biosynthesis in Spirotetronate Antibiotics

  Jie Fang;Yiping Zhang;Lijuan Huang;Xinying Jia

  132
  Citations

• Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A

  Qunfei Zhao;Min Wang;Dongxiao Xu;Qinglin Zhang

  128
  Citations

• Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.

  Steven G. Van Lanen;Tae-jin Oh;Wen Liu;Evelyn Wendt-Pienkowski

  128
  Citations

• Characterization of the Azinomycin B Biosynthetic Gene Cluster Revealing a Different Iterative Type I Polyketide Synthase for Naphthoate Biosynthesis

  Qunfei Zhao;Qingli He;Wei Ding;Wei Ding;Mancheng Tang

  124
  Citations

• Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model

  Wen Liu;Joachim Ahlert;Qunjie Gao;Evelyn Wendt-Pienkowski

  123
  Citations

• A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis

  Jian Zhang;Steven G. Van Lanen;Jianhua Ju;Wen Liu

  119
  Citations

• Biosynthesis of thiopeptide antibiotics and their pathway engineering

  Qi Zhang;Wen Liu

  115
  Citations