World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
26461
World Ranking
3845
National Ranking
1904

Research.com Recognitions

  • 2015 - Promega Biotechnology Research Award, American Society for Microbiology
  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Ben Shen is affiliated with the Scripps Research Institute in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a strong focus on Molecular Biology and Pharmacology. Other areas of study include Organic Chemistry, Biotechnology, and Materials Chemistry.

The scientist's scholarly output covers several specific topics, such as:

  • Microbial Natural Products and Biosynthesis
  • Genomics and Phylogenetic Studies
  • Plant Biochemistry and Biosynthesis
  • Chemical Synthesis and Analysis
  • Phytochemical Compounds Biological Activities
  • Synthetic Organic Chemistry Methods
  • Carbohydrate Chemistry and Synthesis

Ben Shen's publishing record shows frequent contributions to prominent journals, including:

  • Journal of the American Chemical Society
  • Journal of Industrial Microbiology & Biotechnology
  • Nature Chemical Biology
  • ACS Chemical Biology
  • Biochemistry

Coauthorship collaborations are notable with researchers such as Dong Yang, Edward Kalkreuter, Ajeeth Adhikari, Andrew D. Steele, and Christiana N. Teijaro, reflecting a consistent partnership network.

Among the recent papers authored or coauthored by Ben Shen are:

  • "Divergent synthesis of complex diterpenes through a hybrid oxidative approach" (2020, Science)
  • "Challenges and opportunities to develop enediyne natural products as payloads for antibody-drug conjugates" (2021, Antibody Therapeutics)
  • "Platensimycin-Encapsulated Poly(lactic-co-glycolic acid) and Poly(amidoamine) Dendrimers Nanoparticles with Enhanced Anti-Staphylococcal Activity in Vivo" (2020, Bioconjugate Chemistry)
  • "Platensimycin-Encapsulated Liposomes or Micelles as Biosafe Nanoantibiotics Exhibited Strong Antibacterial Activities against Methicillin-Resistant Staphylococcus aureus Infection in Mice" (2020, Molecular Pharmaceutics)
  • "Characterization of TnmH as an O-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody-Tiancimycin Conjugates" (2020, Journal of Medicinal Chemistry)

Throughout their career, Ben Shen has been recognized with awards including the Promega Biotechnology Research Award from the American Society for Microbiology in 2015 and election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2011.

Best Publications

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

    Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers

  • Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

    Tilman Schneider-Poetsch;Jianhua Ju;Daniel E Eyler;Yongjun Dang

  • Minimum Information about a Biosynthetic Gene cluster.

    Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  • Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms.

    Ben Shen

  • Decoding Human Cytomegalovirus

    Noam Stern-Ginossar;Ben Weisburd;Annette Michalski;Vu Thuy Khanh Le

  • A New Golden Age of Natural Products Drug Discovery

    Ben Shen

  • Antitumor antibiotics: bleomycin, enediynes, and mitomycin.

    Ute Galm;Martin H. Hager;Steven G. Van Lanen;Jianhua Ju

  • Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution.

    Sooncheol Lee;Botao Liu;Soohyun Lee;Sheng-Xiong Huang

  • Synthetic biology to access and expand nature's chemical diversity.

    Michael J. Smanski;Hui Zhou;Jan Claesen;Ben Shen

  • A genomics-guided approach for discovering and expressing cryptic metabolic pathways.

    Emmanuel Zazopoulos;Kexue Huang;Alfredo Staffa;Wen Liu

  • The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase

    Liangcheng Du;César Sánchez;Mei Chen;Daniel J Edwards

  • Biosynthesis of the enediyne antitumor antibiotic C-1027.

    Wen Liu;Steven D. Christenson;Scott Standage;Ben Shen

  • Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis

    Yi Qiang Cheng;Gong Li Tang;Ben Shen

  • Hybrid peptide-polyketide natural products: biosynthesis and prospects toward engineering novel molecules.

    Liangcheng Du;César Sánchez;Ben Shen

  • Intrinsic fluorescence from DNA can be enhanced by metallic particles.

    Joseph R. Lakowicz;Ben Shen;Zygmunt Gryczynski;Sabato D'Auria

  • Quantitative profiling of initiating ribosomes in vivo

    Xiangwei Gao;Ji Wan;Botao Liu;Ming Ma

  • Thiopeptide Biosynthesis Featuring Ribosomally Synthesized Precursor Peptides and Conserved Posttranslational Modifications

    Rijing Liao;Lian Duan;Chun Lei;Haixue Pan

  • Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide–polyketide antitumor drug bleomycin

    César Sánchez;Liangcheng Du;Daniel J Edwards;Michael D Toney

  • Microbial genomics for the improvement of natural product discovery.

    Steven G Van Lanen;Ben Shen

  • Synthetic biology to access and expand nature's chemical diversity

    Jan Claesen;Ben Shen;Michael A. Fischbach;Hui Zhou

Frequent Co-Authors

Jianhua Ju
Jianhua Ju Chinese Academy of Sciences
Sheng-Xiong Huang
Sheng-Xiong Huang Chinese Academy of Sciences
Wen Liu
Wen Liu Chinese Academy of Sciences
Rui Zhang
Rui Zhang National University of Singapore
Rong Zhang
Rong Zhang Nanjing University
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory
Liangcheng Du
Liangcheng Du University of Nebraska–Lincoln
George N. Phillips
George N. Phillips Rice University
Yi Shi
Yi Shi Nanjing University
Takao Someya
Takao Someya University of Tokyo

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