D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 74 Citations 21,180 393 World Ranking 3482 National Ranking 1783

Research.com Recognitions

Awards & Achievements

2015 - Promega Biotechnology Research Award, American Society for Microbiology

2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

Biochemistry, Gene cluster, Polyketide, Stereochemistry and Polyketide synthase are his primary areas of study. His work investigates the relationship between Biochemistry and topics such as Streptomyces that intersect with problems in Platensimycin. His Gene cluster study combines topics in areas such as Streptomycetaceae, Sequence analysis and Mutant.

His biological study spans a wide range of topics, including Streptomyces verticillus, Multifunctional Enzymes and Peptide. His studies in Stereochemistry integrate themes in fields like Active site, Oxidase test and Enzyme. His Polyketide synthase research includes themes of Polyketide biosynthesis, Nonribosomal peptide and Sequence alignment.

His most cited work include:

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (1048 citations)
  • Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin (542 citations)
  • Decoding Human Cytomegalovirus (422 citations)

What are the main themes of his work throughout his whole career to date?

Ben Shen focuses on Biochemistry, Stereochemistry, Biosynthesis, Streptomyces and Gene cluster. His study in Biochemistry concentrates on Polyketide, Gene, Polyketide synthase, Platensimycin and Mutant. Ben Shen combines subjects such as Acyltransferase, Streptomyces griseus and Acyl carrier protein with his study of Polyketide.

The various areas that he examines in his Stereochemistry study include Leinamycin and Enzyme, Active site. He works mostly in the field of Biosynthesis, limiting it down to topics relating to Natural product and, in certain cases, Drug discovery. His Gene cluster research incorporates elements of Cloning, Streptomyces verticillus and Sequence analysis.

He most often published in these fields:

  • Biochemistry (39.72%)
  • Stereochemistry (28.04%)
  • Biosynthesis (28.74%)

What were the highlights of his more recent work (between 2015-2021)?

  • Biosynthesis (28.74%)
  • Biochemistry (39.72%)
  • Platensimycin (11.68%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Biosynthesis, Biochemistry, Platensimycin, Stereochemistry and Streptomyces. Ben Shen works mostly in the field of Biosynthesis, limiting it down to topics relating to Natural product and, in certain cases, Computational biology, as a part of the same area of interest. His Platensimycin research integrates issues from Antibacterial activity, Staphylococcus aureus, Fatty Acid Synthases, Streptomyces platensis and In vivo.

His study in Stereochemistry is interdisciplinary in nature, drawing from both Polyketide synthase, Polyketide, Active site and Stereoselectivity. His Streptomyces study combines topics from a wide range of disciplines, such as Protein structure, Titer and Enediyne. His Gene cluster study deals with the bigger picture of Gene.

Between 2015 and 2021, his most popular works were:

  • Synthetic biology to access and expand nature's chemical diversity. (262 citations)
  • Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function (55 citations)
  • Strain Prioritization and Genome Mining for Enediyne Natural Products. (39 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

His primary scientific interests are in Biochemistry, Gene, Platensimycin, Streptomyces and Computational biology. His Biochemistry research focuses on Biosynthesis, Mutant and Fermentation. His study in the field of Gene cluster and Regulator gene is also linked to topics like Micrococcal nuclease.

His research in Platensimycin intersects with topics in Streptomyces platensis and Fatty Acid Synthases. His work carried out in the field of Streptomyces brings together such families of science as Function, Small molecule and Cytochrome P450, Enzyme. His research on Computational biology also deals with topics like

  • Genome which is related to area like DNA sequencing, Drug discovery and Enediyne,
  • Natural product which connect with Leinamycin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers.
Natural Product Reports (2013)

1636 Citations

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

Tilman Schneider-Poetsch;Jianhua Ju;Daniel E Eyler;Yongjun Dang.
Nature Chemical Biology (2010)

881 Citations

Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms.

Ben Shen.
Current Opinion in Chemical Biology (2003)

672 Citations

Minimum Information about a Biosynthetic Gene cluster.

Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings.
Nature Chemical Biology (2015)

654 Citations

Decoding Human Cytomegalovirus

Noam Stern-Ginossar;Ben Weisburd;Annette Michalski;Vu Thuy Khanh Le.
Science (2012)

622 Citations

Antitumor antibiotics: bleomycin, enediynes, and mitomycin.

Ute Galm;Martin H. Hager;Steven G. Van Lanen;Jianhua Ju.
Chemical Reviews (2005)

589 Citations

Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution.

Sooncheol Lee;Botao Liu;Soohyun Lee;Sheng-Xiong Huang.
Proceedings of the National Academy of Sciences of the United States of America (2012)

477 Citations

A New Golden Age of Natural Products Drug Discovery

Ben Shen.
Cell (2015)

416 Citations

A genomics-guided approach for discovering and expressing cryptic metabolic pathways.

Emmanuel Zazopoulos;Kexue Huang;Alfredo Staffa;Wen Liu.
Nature Biotechnology (2003)

399 Citations

The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase

Liangcheng Du;César Sánchez;Mei Chen;Daniel J Edwards.
Chemistry & Biology (2000)

375 Citations

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