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Molecular Biology

D-Index
99
Citations
33608
World Ranking
556
National Ranking
304

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Myron F. Goodman is affiliated with the University of Southern California in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology, genetics, infectious diseases, immunology, and molecular medicine within these broader fields.

Their scientific work covers various topics including:

  • DNA Repair Mechanisms
  • Bacterial Genetics and Biotechnology
  • DNA and Nucleic Acid Chemistry
  • RNA and protein synthesis mechanisms
  • CRISPR and Genetic Engineering
  • T-cell and B-cell Immunology
  • Antibiotic Resistance in Bacteria

Goodman has authored numerous publications, with frequent contributions to journals such as Nucleic Acids Research, where they have published seven papers. Other notable venues include bioRxiv (Cold Spring Harbor Laboratory), Biochemistry, and Microbiology and Molecular Biology Reviews.

Selected recent papers include:

  • "Genomic landscape of single-stranded DNA gapped intermediates in Escherichia coli" (2021), Nucleic Acids Research
  • "Single-molecule live-cell imaging reveals RecB-dependent function of DNA polymerase IV in double strand break repair" (2020), Nucleic Acids Research
  • "Generation and Repair of Postreplication Gaps in Escherichia coli" (2023), Microbiology and Molecular Biology Reviews
  • "RecA and SSB genome-wide distribution in ssDNA gaps and ends in Escherichia coli" (2023), Nucleic Acids Research
  • "The mRNA tether model for activation-induced deaminase and its relevance for Ig somatic hypermutation and class switch recombination" (2021), DNA Repair

Frequent coauthors with whom Goodman has collaborated multiple times include Phuong Pham, Michael M. Cox, Roger Woodgate, Antoine M. van Oijen, and Andrew Robinson. These collaborations have contributed to expanding research in molecular biology and DNA repair mechanisms.

Goodman was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • The importance of repairing stalled replication forks

    Michael M. Cox;Myron F. Goodman;Kenneth N. Kreuzer;David J. Sherratt

  • Error-prone repair DNA polymerases in prokaryotes and eukaryotes.

    Myron F. Goodman

  • The Y-Family of DNA Polymerases

    Haruo Ohmori;Errol C. Friedberg;Robert P.P. Fuchs;Myron F. Goodman

  • Fidelity mechanisms in DNA replication.

    Harrison Echols;Myron F. Goodman

  • Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

    Ronda Bransteitter;Phuong Pham;Matthew D. Scharff;Myron F. Goodman

  • Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation.

    Phuong Pham;Ronda Bransteitter;John Petruska;Myron F. Goodman

  • UmuD′2C is an error-prone DNA polymerase, Escherichia coli pol V

    Mengjia Tang;Xuan Shen;Ekaterina G. Frank;Mike O’Donnell

  • The Biochemistry of Somatic Hypermutation

    Jonathan U. Peled;Fei Li Kuang;Maria D. Iglesias-Ussel;Sergio Roa

  • Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis

    Mengjia Tang;Phuong Pham;Xuan Shen;John-Stephen Taylor

  • Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR

    Mei mei Huang;Norman Arnheim;Myron F. Goodman

  • DNA polymerase insertion fidelity. Gel assay for site-specific kinetics.

    M S Boosalis;J Petruska;M F Goodman

  • Comparison between DNA melting thermodynamics and DNA polymerase fidelity.

    John Petruska;Myron F. Goodman;Michael S. Boosalis;Lawrence C. Sowers

  • A Biochemically Defined System for Mammalian Nonhomologous DNA End Joining

    Yunmei Ma;Haihui Lu;Brigette Tippin;Myron F. Goodman

  • Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase.

    L V Mendelman;J Petruska;M F Goodman

  • APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA.

    Linda Chelico;Phuong Pham;Peter Calabrese;Myron F Goodman

  • Translesion DNA Polymerases

    Myron F. Goodman;Roger Woodgate

  • Nearest neighbor influences on DNA polymerase insertion fidelity.

    L V Mendelman;M S Boosalis;J Petruska;M F Goodman

  • Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies.

    Steven Creighton;Linda B. Bloom;Myron F. Goodman

  • The APOBEC-2 crystal structure and functional implications for the deaminase AID

    Courtney Prochnow;Ronda Bransteitter;Michael G. Klein;Myron F. Goodman

  • Hydrogen bonding revisited: Geometric selection as a principal determinant of DNA replication fidelity

    Myron F. Goodman

Frequent Co-Authors

Roger Woodgate
Roger Woodgate National Institutes of Health
Mike O'Donnell
Mike O'Donnell Rockefeller University
Ramon Eritja
Ramon Eritja Spanish National Research Council
Michael M. Cox
Michael M. Cox University of Wisconsin–Madison
Samuel H. Wilson
Samuel H. Wilson National Institutes of Health
Lawrence C. Sowers
Lawrence C. Sowers The University of Texas Medical Branch at Galveston
Jan Florián
Jan Florián Loyola University Chicago
Antoine M. van Oijen
Antoine M. van Oijen Illawarra Health and Medical Research Institute
William A. Beard
William A. Beard National Institutes of Health
Arieh Warshel
Arieh Warshel University of Southern California

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