2017 - Fellow of the American Association for the Advancement of Science (AAAS)
Reuben S. Harris undertakes multidisciplinary investigations into Enzyme and Mutation in his work. With his scientific publications, his incorporates both Mutation and Gene. He conducts interdisciplinary study in the fields of Gene and Genetics through his research. His Genetics study frequently links to related topics such as Virus. Reuben S. Harris performs multidisciplinary study in Virus and Drug resistance in his work. Borrowing concepts from Enzyme, Reuben S. Harris weaves in ideas under Drug resistance. His Protease study often links to related topics such as Biochemistry. His research on Biochemistry often connects related topics like Protease. His research on Antiretroviral therapy often connects related areas such as Protease inhibitor (pharmacology).
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AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
Svend K. Petersen-Mahrt;Reuben S. Harris;Michael S. Neuberger.
Retroviral restriction by APOBEC proteins
Reuben S. Harris;Mark T. Liddament.
Nature Reviews Immunology (2004)
APOBEC3B is an enzymatic source of mutation in breast cancer
Michael B. Burns;Lela Lackey;Michael A. Carpenter;Anurag Rathore.
RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators.
Reuben S. Harris;Svend K. Petersen-Mahrt;Michael S. Neuberger.
Molecular Cell (2002)
Evidence for APOBEC3B mutagenesis in multiple human cancers
Michael B Burns;Nuri A Temiz;Reuben S Harris.
Nature Genetics (2013)
The Vif Protein of HIV Triggers Degradation of the Human Antiretroviral DNA Deaminase APOBEC3G
Silvestro G Conticello;Reuben S Harris;Michael S Neuberger.
Current Biology (2003)
APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo.
Mark T. Liddament;William L. Brown;April J. Schumacher;Reuben S. Harris.
Current Biology (2004)
APOBECs and virus restriction
Reuben S. Harris;Jaquelin P. Dudley.
Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo.
Rupert C.L. Beale;Svend K. Petersen-Mahrt;Svend K. Petersen-Mahrt;Ian N. Watt;Reuben S. Harris.
Journal of Molecular Biology (2004)
APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity
Charles Swanton;Nicholas McGranahan;Gabriel J. Starrett;Reuben S. Harris.
Cancer Discovery (2015)
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