2017 - Fellow of the American Association for the Advancement of Science (AAAS)
Reuben S. Harris mostly deals with Genetics, APOBEC3A, APOBEC3G, DNA and Cytidine deaminase. His Genetics research focuses on Somatic hypermutation, Adaptive mutation, Mutation, APOBEC1 and APOBEC Deaminases. His work deals with themes such as Cancer, Cancer research and DNA damage, which intersect with Mutation.
Reuben S. Harris studied APOBEC3A and RNA editing that intersect with Cytidine deaminase activity. His studies deal with areas such as Complementary DNA and Retrotransposon as well as APOBEC3G. His DNA study integrates concerns from other disciplines, such as Gene, Deamination and DNA deamination.
Reuben S. Harris focuses on DNA, Genetics, APOBEC3G, Cytidine deaminase and Virology. Reuben S. Harris has researched DNA in several fields, including Molecular biology and Cell biology. His Genetics study is mostly concerned with Mutation, Somatic hypermutation, Gene, Mutation and Adaptive mutation.
His Mutation research is multidisciplinary, relying on both Cancer, Breast cancer, Cancer research and Kataegis. His biological study spans a wide range of topics, including Complementary DNA, APOBEC1 and Infectivity. His Cytidine deaminase study incorporates themes from Plasma protein binding and Ubiquitin.
His main research concerns DNA, Cell biology, APOBEC, Cancer research and APOBEC3G. His work carried out in the field of DNA brings together such families of science as Monoclonal antibody, Small molecule and Enzyme. His APOBEC research incorporates elements of RNA, Cas9 and DNA sequencing.
His Cancer research study combines topics from a wide range of disciplines, such as Immune checkpoint, Cancer, Immunotherapy, Antigen and Lung cancer. His studies examine the connections between APOBEC3G and genetics, as well as such issues in Simian immunodeficiency virus, with regards to Lentivirus, Viral infectivity factor, Viral evolution and Cell. His APOBEC3A study introduces a deeper knowledge of Genetics.
Reuben S. Harris mainly investigates Cell biology, APOBEC, Cancer research, DNA and Cancer. His research integrates issues of RNA and Cytosine in his study of APOBEC. His Cancer research study also includes fields such as
His DNA research focuses on APOBEC3A in particular. His APOBEC3A study is associated with Genetics. He combines subjects such as genomic DNA, Molecular biology, Innate immune system and Monoclonal with his study of Cancer.
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AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
Svend K. Petersen-Mahrt;Reuben S. Harris;Michael S. Neuberger.
Nature (2002)
Retroviral restriction by APOBEC proteins
Reuben S. Harris;Mark T. Liddament.
Nature Reviews Immunology (2004)
RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators.
Reuben S. Harris;Svend K. Petersen-Mahrt;Michael S. Neuberger.
Molecular Cell (2002)
The Vif Protein of HIV Triggers Degradation of the Human Antiretroviral DNA Deaminase APOBEC3G
Silvestro G Conticello;Reuben S Harris;Michael S Neuberger.
Current Biology (2003)
APOBEC3B is an enzymatic source of mutation in breast cancer
Michael B. Burns;Lela Lackey;Michael A. Carpenter;Anurag Rathore.
Nature (2013)
APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo.
Mark T. Liddament;William L. Brown;April J. Schumacher;Reuben S. Harris.
Current Biology (2004)
Evidence for APOBEC3B mutagenesis in multiple human cancers
Michael B Burns;Nuri A Temiz;Reuben S Harris.
Nature Genetics (2013)
Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo.
Rupert C.L. Beale;Svend K. Petersen-Mahrt;Svend K. Petersen-Mahrt;Ian N. Watt;Reuben S. Harris.
Journal of Molecular Biology (2004)
APOBECs and virus restriction
Reuben S. Harris;Jaquelin P. Dudley.
Virology (2015)
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection
Stefanie Jäger;Dong Young Kim;Judd F. Hultquist;Keisuke Shindo.
Nature (2012)
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