2026 Reuben S. Harris: Genetics Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Genetics	86	1252	1184	595	557	333	29083

Research.com Recognitions

2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Reuben S. Harris is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research spans biochemistry, genetics, molecular biology, and medicine, with a particular focus on molecular biology, oncology, infectious diseases, epidemiology, and cancer research.

Harris's work encompasses multiple areas of study, including:

Cancer Genomics and Diagnostics
RNA modifications and cancer
CRISPR and Genetic Engineering
HIV Research and Treatment
Cytomegalovirus and herpesvirus research
SARS-CoV-2 and COVID-19 Research
Epigenetics and DNA Methylation

They have contributed extensively to the scientific literature with numerous publications in prominent journals and platforms. Frequent publication venues include:

bioRxiv (Cold Spring Harbor Laboratory)
Cancer Research
Clinical Cancer Research
Nature Communications
Nature Genetics

Some of Harris's recent papers are:

"Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors," 2023, Science Advances
"Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA," 2022, Nature
"APOBEC3A catalyzes mutation and drives carcinogenesis in vivo," 2020, The Journal of Experimental Medicine
"Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution," 2021, Cancer Discovery
"SARS-CoV-2 3CL ^pro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC376," 2022, Science Translational Medicine

Frequent co-authors collaborating with Harris include:

Michael A. Carpenter
Hideki Aihara
Prokopios P. Argyris
Nuri A. Temiz
Cameron Durfee

Harris's research contributions have earned recognition such as being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2017.

Best Publications

DNA deamination mediates innate immunity to (retro)viral infection

Michael Malim;Ann Sheehy;Reuben Harris;Kate Bishop

1757
Citations
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

Svend K. Petersen-Mahrt;Reuben S. Harris;Michael S. Neuberger

1166
Citations
APOBEC3B is an enzymatic source of mutation in breast cancer

Michael B. Burns;Lela Lackey;Michael A. Carpenter;Anurag Rathore

898
Citations
Retroviral restriction by APOBEC proteins

Reuben S. Harris;Mark T. Liddament

868
Citations
Evidence for APOBEC3B mutagenesis in multiple human cancers

Michael B Burns;Nuri A Temiz;Reuben S Harris

813
Citations
RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators.

Reuben S. Harris;Svend K. Petersen-Mahrt;Michael S. Neuberger

758
Citations
The Vif Protein of HIV Triggers Degradation of the Human Antiretroviral DNA Deaminase APOBEC3G

Silvestro G Conticello;Reuben S Harris;Michael S Neuberger

639
Citations
APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo.

Mark T. Liddament;William L. Brown;April J. Schumacher;Reuben S. Harris

606
Citations
APOBECs and virus restriction

Reuben S. Harris;Jaquelin P. Dudley

568
Citations
APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

Charles Swanton;Nicholas McGranahan;Gabriel J. Starrett;Reuben S. Harris

493
Citations
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection

Stefanie Jäger;Dong Young Kim;Judd F. Hultquist;Keisuke Shindo

433
Citations
Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo.

Rupert C.L. Beale;Svend K. Petersen-Mahrt;Svend K. Petersen-Mahrt;Ian N. Watt;Reuben S. Harris

411
Citations
Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

Eric W. Refsland;Mark D. Stenglein;Keisuke Shindo;John S. Albin

408
Citations
Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1

Judd F. Hultquist;Joy A. Lengyel;Eric W. Refsland;Rebecca S. LaRue

407
Citations
APOBEC3 proteins mediate the clearance of foreign DNA from human cells.

Mark D Stenglein;Mark D Stenglein;Michael B Burns;Ming Li;Joy Lengyel

387
Citations
The Restriction Factors of Human Immunodeficiency Virus

Reuben S. Harris;Judd F. Hultquist;David T. Evans

348
Citations
Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration

Jean L. Mbisa;Rebekah Barr;James A. Thomas;Nick Vandegraaff

345
Citations
Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

Kuan Ming Chen;Elena Harjes;Phillip J. Gross;Amr Fahmy

342
Citations
APOBEC3B and APOBEC3F Inhibit L1 Retrotransposition by a DNA Deamination-independent Mechanism

Mark D. Stenglein;Reuben S. Harris

336
Citations
The SOS response regulates adaptive mutation

Gregory J. McKenzie;Reuben S. Harris;Reuben S. Harris;Peter L. Lee;Susan M. Rosenberg;Susan M. Rosenberg

327
Citations

Frequent Co-Authors

Susan M. Rosenberg Baylor College of Medicine

Nevan J. Krogan University of California, San Francisco

Yuri L. Lyubchenko University of Nebraska Medical Center

Celia A. Schiffer University of Massachusetts Chan Medical School

Charles Swanton The Francis Crick Institute

Yoshio Koyanagi Kyoto University

Jeffrey R. Johnson Icahn School of Medicine at Mount Sinai

Michael S. Neuberger MRC Laboratory of Molecular Biology

Nicholas McGranahan University College London

David A. Largaespada University of Minnesota

External Links

Personal website of Reuben S. Harris

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