2026 David R. Liu: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	137	139	123	89	78	435	95292
Biology and Biochemistry	143	235	206	161	139	542	101072

Research.com Recognitions

2026 - Research.com Molecular Biology in United States Leader Award
2020 - Member of the National Academy of Medicine (NAM)
2020 - Fellow of the American Association for the Advancement of Science (AAAS)
2006 - ACS Award in Pure Chemistry, American Chemical Society (ACS)
2002 - Fellow of Alfred P. Sloan Foundation

Overview

David R. Liu is affiliated with the Broad Institute in the United States. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with significant contributions to Molecular Biology, Genetics, Immunology, Epidemiology, and Oncology.

The scientist's main research topics include:

CRISPR and Genetic Engineering
RNA regulation and disease
Virus-based gene therapy research
RNA and protein synthesis mechanisms
Advanced biosensing and bioanalysis techniques
RNA Interference and Gene Delivery
Cytomegalovirus and herpesvirus research

Frequent co-authors in their work have been:

Gregory A. Newby
Aditya Raguram
Jessie R. Davis
Jonathan M. Levy
Luke W. Koblan

David R. Liu's publications have appeared predominantly in the following venues:

Nature Biotechnology
bioRxiv (Cold Spring Harbor Laboratory)
Nature Communications
Nature Biomedical Engineering
Cell

Notable recent papers include:

Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors, 2020, Nature Biotechnology
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity, 2020, Nature Biotechnology
Prime genome editing in rice and wheat, 2020, Nature Biotechnology
Enhanced prime editing systems by manipulating cellular determinants of editing outcomes, 2021, Cell
A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing, 2020, Nature

David R. Liu has been recognized with several awards including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2020 and a Fellow of the Alfred P. Sloan Foundation in 2002.

Best Publications

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Mamta V. Tahiliani;Kian Peng Koh;Yinghua Shen;William Abraham Pastor

6284
Citations
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor;Yongjoo B. Kim;Yongjoo B. Kim;Michael S. Packer;Michael S. Packer;John A. Zuris;John A. Zuris

4661
Citations
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

Nicole M. Gaudelli;Alexis C. Komor;Holly A. Rees;Holly A. Rees;Holly A. Rees;Michael S. Packer

3437
Citations
Search-and-replace genome editing without double-strand breaks or donor DNA

Andrew V. Anzalone;Andrew V. Anzalone;Andrew V. Anzalone;Peyton B. Randolph;Peyton B. Randolph;Peyton B. Randolph;Jessie R. Davis;Jessie R. Davis;Jessie R. Davis;Alexander A. Sousa;Alexander A. Sousa;Alexander A. Sousa

3408
Citations
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists

Da Wei Huang;Brad T. Sherman;Qina Tan;Joseph Kir

2360
Citations
Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial

Eugene D. Kwon;Charles G. Drake;Howard I. Scher;Karim Fizazi

1902
Citations
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

Vikram Pattanayak;Steven Lin;John P Guilinger;Enbo Ma

1768
Citations
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Andrew V. Anzalone;Luke W. Koblan;Luke W. Koblan;Luke W. Koblan;David R. Liu;David R. Liu;David R. Liu

1653
Citations
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

John A. Zuris;David B. Thompson;Yilai Shu;John Paul Guilinger

1485
Citations
Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

Johnny H. Hu;Shannon M. Miller;Shannon M. Miller;Shannon M. Miller;Maarten H. Geurts;Maarten H. Geurts;Maarten H. Geurts;Weixin Tang;Weixin Tang;Weixin Tang

1443
Citations
A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

Livnat Jerby-Arnon;Parin Shah;Michael S. Cuoco;Christopher Rodman

1386
Citations
Base editing: precision chemistry on the genome and transcriptome of living cells

Holly A. Rees;David R. Liu;David R. Liu;David R. Liu

1351
Citations
Sequence-controlled polymers.

Jean-François Lutz;Makoto Ouchi;David R. Liu;Mitsuo Sawamoto

1326
Citations
CRISPResso2 provides accurate and rapid genome editing sequence analysis.

Clement K;Rees H;Canver Mc;Canver Mc;Gehrke Jm

1174
Citations
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.

Alexis C. Komor;Alexis C. Komor;Alexis C. Komor;Ahmed H. Badran;Ahmed H. Badran;Ahmed H. Badran;David R. Liu;David R. Liu;David R. Liu

1109
Citations
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

John Paul Guilinger;David B. Thompson;David B. Thompson;David R. Liu;David R. Liu

1060
Citations
Methods for the directed evolution of proteins

Michael S. Packer;David R. Liu

980
Citations
A Small Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

Justin K. Ichida;Joel Blanchard;Kelvin Lam;Esther Y. Son

939
Citations
The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

Yun Huang;William A. Pastor;Yinghua Shen;Mamta Tahiliani

848
Citations
Brivanib Versus Sorafenib As First-Line Therapy in Patients With Unresectable, Advanced Hepatocellular Carcinoma: Results From the Randomized Phase III BRISK-FL Study

Philip J. Johnson;Shukui Qin;Joong Won Park;Ronnie T.P. Poon

810
Citations