D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 115 Citations 64,391 512 World Ranking 520 National Ranking 354

Research.com Recognitions

Awards & Achievements

2020 - Fellow of the American Association for the Advancement of Science (AAAS)

2002 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

David R. Liu mainly focuses on Computational biology, Genome editing, DNA, Genetics and Cas9. His Computational biology study incorporates themes from Genome, Gene, CRISPR and Small molecule. His Guide RNA study, which is part of a larger body of work in Genome editing, is frequently linked to Software, bridging the gap between disciplines.

His research integrates issues of RNA, Human genome and Point mutation in his study of DNA. His Point mutation study integrates concerns from other disciplines, such as genomic DNA and DNA glycosylase. Many of his studies involve connections with topics such as Protein engineering and Genetics.

His most cited work include:

  • Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1 (4043 citations)
  • Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage (1782 citations)
  • Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage (1782 citations)

What are the main themes of his work throughout his whole career to date?

David R. Liu mainly investigates Computational biology, DNA, Biochemistry, Genome editing and Genetics. David R. Liu studied Computational biology and Cas9 that intersect with Nuclease. His DNA study also includes

  • RNA and related Molecular biology,
  • Mutation which connect with Cell biology.

He interconnects HEK 293 cells, Base pair and Human genome in the investigation of issues within Genome editing. His is involved in several facets of Genetics study, as is seen by his studies on Directed evolution, Point mutation and Transcription activator-like effector nuclease. His work carried out in the field of Nucleic acid brings together such families of science as Combinatorial chemistry, Sequence and Polymer.

He most often published in these fields:

  • Computational biology (62.32%)
  • DNA (34.78%)
  • Biochemistry (26.23%)

What were the highlights of his more recent work (between 2019-2021)?

  • Computational biology (62.32%)
  • Genome editing (40.72%)
  • CRISPR (23.19%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Computational biology, Genome editing, CRISPR, Gene and DNA. His work deals with themes such as RNA, HEK 293 cells and Cas9, Guide RNA, which intersect with Computational biology. His study explores the link between Cas9 and topics such as genomic DNA that cross with problems in Whole genome sequencing.

His studies deal with areas such as Base pair and Dna breaks as well as Genome editing. His DNA research includes elements of Nucleic acid and Deamination. His Point mutation study deals with the bigger picture of Genetics.

Between 2019 and 2021, his most popular works were:

  • Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors. (165 citations)
  • Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors. (165 citations)
  • Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors. (165 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His scientific interests lie mostly in Computational biology, Mutation, DNA, Genome editing and Cas9. His Mutation study combines topics in areas such as RNA and Cytosine. His DNA research incorporates themes from Deamination and Guide RNA.

His Guide RNA research entails a greater understanding of Genetics. Genome and CRISPR are the subject areas of his Genome editing study. David R. Liu combines subjects such as HEK 293 cells, Enhancer and Deoxyadenosine with his study of Cas9.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Mamta V. Tahiliani;Kian Peng Koh;Yinghua Shen;William Abraham Pastor.
Science (2009)

5654 Citations

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor;Yongjoo B. Kim;Yongjoo B. Kim;Michael S. Packer;Michael S. Packer;John A. Zuris;John A. Zuris.
Nature (2016)

2191 Citations

DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists

Da Wei Huang;Brad T. Sherman;Qina Tan;Joseph Kir.
Nucleic Acids Research (2007)

1853 Citations

Search-and-replace genome editing without double-strand breaks or donor DNA

Andrew V. Anzalone;Andrew V. Anzalone;Andrew V. Anzalone;Peyton B. Randolph;Peyton B. Randolph;Peyton B. Randolph;Jessie R. Davis;Jessie R. Davis;Jessie R. Davis;Alexander A. Sousa;Alexander A. Sousa;Alexander A. Sousa.
Nature (2019)

1841 Citations

Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial

Eugene D. Kwon;Charles G. Drake;Howard I. Scher;Karim Fizazi.
Lancet Oncology (2014)

1592 Citations

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

Vikram Pattanayak;Steven Lin;John P Guilinger;Enbo Ma.
Nature Biotechnology (2013)

1581 Citations

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

Nicole M. Gaudelli;Alexis C. Komor;Holly A. Rees;Holly A. Rees;Holly A. Rees;Michael S. Packer.
Nature (2017)

1464 Citations

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

John A. Zuris;David B. Thompson;Yilai Shu;John Paul Guilinger.
Nature Biotechnology (2015)

1227 Citations

Sequence-controlled polymers.

Jean-François Lutz;Makoto Ouchi;David R. Liu;Mitsuo Sawamoto.
Science (2013)

1003 Citations

A Small Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

Justin K. Ichida;Joel Blanchard;Kelvin Lam;Esther Y. Son.
Cell Stem Cell (2009)

891 Citations

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