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Genetics

D-Index
57
Citations
67784
World Ranking
3346
National Ranking
404

Overview

Graham R. Bignell is affiliated with the Wellcome Sanger Institute in the United Kingdom. Their research spans several areas within the Agricultural and Biological Sciences, with a focus on Biochemistry, Horticulture, and Plant Science.

Their work covers key topics including Traditional and Medicinal Uses of Annonaceae, Cocoa and Sweet Potato Agronomy, and Banana Cultivation and Research.

Recent publications include the following papers:

  • Integrating multiomics and modern breeding tools for accelerating genetic improvement in Annonas (2025, Functional & Integrative Genomics)
  • Processed pseudogenes acquired somatically during cancer development (2020, UNC Libraries)

Frequent collaborators in their research include Shri Hari Prasad, Rhys G. R. Copeland, Vanika Garg, Annapurna Chitikineni, and Robert J Henry.

Their research has appeared in venues such as Functional & Integrative Genomics and UNC Libraries.

Best Publications

  • Mutations of the BRAF gene in human cancer

    Helen Davies;Graham R. Bignell;Charles Cox;Philip Stephens

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Identification of the breast cancer susceptibility gene BRCA2

    Wooster R;Bignell G;Lancaster J;Swift S

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Systematic identification of genomic markers of drug sensitivity in cancer cells

    Mathew J. Garnett;Elena J. Edelman;Sonja J. Heidorn;Christopher Greenman;Christopher Greenman

  • Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

    Philip J. Stephens;Chris D. Greenman;Beiyuan Fu;Fengtang Yang

  • A Landscape of Pharmacogenomic Interactions in Cancer

    Francesco Iorio;Francesco Iorio;Theo A. Knijnenburg;Theo A. Knijnenburg;Daniel J. Vis;Graham R. Bignell

  • A serine/threonine kinase gene defective in Peutz–Jeghers syndrome

    A Hemminki;D Markie;I Tomlinson;E Avizienyte

  • Mutational Processes Molding the Genomes of 21 Breast Cancers

    Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • A comprehensive catalogue of somatic mutations from a human cancer genome

    Erin D. Pleasance;R. Keira Cheetham;Philip J. Stephens;David J. Mcbride

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

    Ignacio Varela;Patrick Tarpey;Keiran Raine;Dachuan Huang

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

  • Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

    Gillian L. Dalgliesh;Kyle Furge;Chris Greenman;Lina Chen

  • Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

    Peter J Campbell;Philip J Stephens;Erin D Pleasance;Sarah O'Meara

  • Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

    Niccolo Bolli;Hervé Avet-Loiseau;David C. Wedge;Peter Van Loo

  • Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

    Gijs Van Haaften;Gillian L Dalgliesh;Helen Davies;Lina Chen

  • Identification of the familial cylindromatosis tumour-suppressor gene.

    Graham R. Bignell;William Warren;Sheila Seal;Meiko Takahashi

  • Signatures of mutation and selection in the cancer genome

    Graham R. Bignell;Chris D. Greenman;Helen Davies;Adam P. Butler

  • Erratum: Identification of the breast cancer susceptibility gene BRCA2

    Richard Wooster;Graham Bignell;Jonathan Lancaster;Sally Swift

Frequent Co-Authors

Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Adam Butler
Adam Butler Wellcome Sanger Institute
Ultan McDermott
Ultan McDermott AstraZeneca (United Kingdom)
Jon W. Teague
Jon W. Teague Wellcome Sanger Institute
Helen Davies
Helen Davies University of Cambridge
Andrew Menzies
Andrew Menzies Wellcome Sanger Institute
Keiran Raine
Keiran Raine Wellcome Sanger Institute
Sarah Edkins
Sarah Edkins Cardiff University
P. Andrew Futreal
P. Andrew Futreal The University of Texas MD Anderson Cancer Center

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