World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
131
Citations
125831
World Ranking
243
National Ranking
126

Research.com Recognitions

  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mutation
  • Cancer

His primary areas of study are Genetics, Human genome, Cancer research, Genome and Mutation. His Human genome research is multidisciplinary, incorporating elements of DNA sequencing and Paired-end tag. His Cancer research research is multidisciplinary, incorporating perspectives in Exome sequencing, Breast cancer, Polycythemia vera and Proto-Oncogene Proteins B-raf.

His Breast cancer study integrates concerns from other disciplines, such as Penetrance, Hereditary breast–ovarian cancer syndrome and Gene mutation. The concepts of his Genome study are interwoven with issues in Gene rearrangement, Germline mutation and Somatic cell. P. Andrew Futreal interconnects Targeted therapy, Carcinoma, Melanoma, Lung cancer and Kinase in the investigation of issues within Mutation.

His most cited work include:

  • A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 (5177 citations)
  • A census of human cancer genes (2604 citations)
  • The cancer genome (2310 citations)

What are the main themes of his work throughout his whole career to date?

P. Andrew Futreal focuses on Genetics, Cancer research, Cancer, Mutation and Gene. His study in Human genome, Genome, Carcinogenesis, X chromosome and Exome sequencing is carried out as part of his Genetics studies. Many of his research projects under Human genome are closely connected to Nucleic acid amplification technique with Nucleic acid amplification technique, tying the diverse disciplines of science together.

His Cancer research research incorporates themes from Germline mutation, Malignancy, Carcinoma, Tumor suppressor gene and Breast cancer. His Cancer research integrates issues from COSMIC cancer database, Somatic cell, Oncology and Pathology. His research investigates the connection between Mutation and topics such as Lung cancer that intersect with problems in Kinase.

He most often published in these fields:

  • Genetics (47.12%)
  • Cancer research (31.73%)
  • Cancer (27.88%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cancer research (31.73%)
  • Cancer (27.88%)
  • Pathology (7.69%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cancer research, Cancer, Pathology, Adenoid cystic carcinoma and Carcinoma. His study in the field of Myeloid leukemia is also linked to topics like Atlas. As part of his studies on Cancer, P. Andrew Futreal often connects relevant subjects like Transcriptome.

His research in Pathology intersects with topics in Gene expression, Gene expression profiling, Tumor microenvironment, Concordance and MSH6. His study in Adenoid cystic carcinoma is interdisciplinary in nature, drawing from both Germline mutation, Malignancy, Head and neck cancer, Carcinogenesis and Intratumoral Genetic Heterogeneity. P. Andrew Futreal works mostly in the field of Carcinoma, limiting it down to topics relating to Metastasis and, in certain cases, Genetic heterogeneity.

Between 2013 and 2021, his most popular works were:

  • Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing (842 citations)
  • Recurrent PTPRB and PLCG1 mutations in angiosarcoma (172 citations)
  • Genomic heterogeneity of multiple synchronous lung cancer (80 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • DNA

The scientist’s investigation covers issues in Cancer research, Genetics, Mutation, PTEN and CDH1. His Cancer research research includes elements of Missense mutation and Angiosarcoma. Genetics is represented through his Exome sequencing, CpG site, Tumor progression, Clear cell and PBRM1 research.

He has included themes like Lung cancer, Human genetics and Cohort in his Mutation study. His PTEN studies intersect with other disciplines such as GATA3, Cell Cycle Gene, Genome, Oncogene and Transcriptome. Borrowing concepts from Cancer, P. Andrew Futreal weaves in ideas under CDH1.

Best Publications

  • Mutations of the BRAF gene in human cancer

    Helen Davies;Graham R. Bignell;Charles Cox;Philip Stephens

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.

    Marco Gerlinger;Andrew J. Rowan;Stuart Horswell;James Larkin

  • The cancer genome

    Michael R. Stratton;Michael R. Stratton;Peter J. Campbell;Peter J. Campbell;P. Andrew Futreal

  • A census of human cancer genes

    P. Andrew Futreal;Lachlan Coin;Mhairi Marshall;Thomas Down

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Systematic identification of genomic markers of drug sensitivity in cancer cells

    Mathew J. Garnett;Elena J. Edelman;Sonja J. Heidorn;Christopher Greenman;Christopher Greenman

  • COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer.

    Simon A. Forbes;Nidhi Bindal;Sally Bamford;Charlotte Cole

  • Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

    Philip J. Stephens;Chris D. Greenman;Beiyuan Fu;Fengtang Yang

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Mutational Processes Molding the Genomes of 21 Breast Cancers

    Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • A comprehensive catalogue of somatic mutations from a human cancer genome

    Erin D. Pleasance;R. Keira Cheetham;Philip J. Stephens;David J. Mcbride

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

    Xose S. Puente;Magda Pinyol;Víctor Quesada;Laura Conde

  • Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

    Ignacio Varela;Patrick Tarpey;Keiran Raine;Dachuan Huang

  • JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis.

    Linda M. Scott;Wei Tong;Ross L. Levine;Mike A. Scott

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

  • The patterns and dynamics of genomic instability in metastatic pancreatic cancer

    Peter J. Campbell;Peter J. Campbell;Shinichi Yachida;Laura J. Mudie;Philip J. Stephens

  • Erratum: Identification of the breast cancer susceptibility gene BRCA2

    Richard Wooster;Graham Bignell;Jonathan Lancaster;Sally Swift

Frequent Co-Authors

Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Patrick S. Tarpey
Patrick S. Tarpey Wellcome Sanger Institute
Helen Davies
Helen Davies University of Cambridge
Sarah Edkins
Sarah Edkins Cardiff University
Graham R. Bignell
Graham R. Bignell Wellcome Sanger Institute
Adam Butler
Adam Butler Wellcome Sanger Institute
Jon W. Teague
Jon W. Teague Wellcome Sanger Institute
Andrew Menzies
Andrew Menzies Wellcome Sanger Institute
Richard Wooster
Richard Wooster Wellcome Sanger Institute

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Related Online Degrees & Career Pathways

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