Adam Butler spends much of his time researching Genetics, Cancer, Mutation, Kataegis and Germline mutation. His study in Genetics concentrates on DNA Mutational Analysis, Somatic evolution in cancer, Exome, Genetic heterogeneity and Exome sequencing. The various areas that Adam Butler examines in his Cancer study include Myeloid, Enasidenib and Midostaurin.
His Mutation study is related to the wider topic of Gene. His work focuses on many connections between Kataegis and other disciplines, such as Point mutation, that overlap with his field of interest in Cancer development, Sequence, Chromothripsis and Gene rearrangement. His work carried out in the field of Germline mutation brings together such families of science as Genome and Human genome.
Genetics, Mutation, Gene, Cancer and Genome are his primary areas of study. His study in Human genome, Germline mutation, Carcinogenesis, DNA Mutational Analysis and Exome are all subfields of Genetics. Adam Butler focuses mostly in the field of Mutation, narrowing it down to topics relating to Histone H3 and, in certain cases, SETD2.
His Cancer study incorporates themes from Cancer research, Kataegis and Point mutation. His studies examine the connections between Cancer research and genetics, as well as such issues in Exome sequencing, with regards to Malignancy and Genetic heterogeneity. His study in Genome is interdisciplinary in nature, drawing from both Genetic variation, Indel, DNA, Mutation rate and Computational biology.
His primary areas of study are Genetics, Gene, Genome, Computational biology and Cancer. Many of his research projects under Genetics are closely connected to Context with Context, tying the diverse disciplines of science together. His work on DNA Mutational Analysis is typically connected to PTEN as part of general Mutation study, connecting several disciplines of science.
As a part of the same scientific family, Adam Butler mostly works in the field of Gene, focusing on Cancer research and, on occasion, Chondroblastoma, Developmental biology, H3F3B and Chordoma. His biological study spans a wide range of topics, including Somatic cell, Mutation rate and Indel. His Cancer study combines topics in areas such as Leukemia and Bioinformatics.
His primary areas of investigation include Genetics, Genome, Mutation, Exome and Gene. While working on this project, Adam Butler studies both Genetics and Recombination signal sequences. His Genome research incorporates themes from Breast cancer, Internal medicine, Genetic variation and Oncology.
He has researched Mutation in several fields, including Carcinogenesis, Cancer and Genomics. His Exome research includes themes of Personal genomics, Whole genome sequencing, Mutation and Deep sequencing. His work on Human genome and Sequence analysis as part of general Gene research is frequently linked to Childhood Acute Lymphoblastic Leukemia and VJ recombination, bridging the gap between disciplines.
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Signatures of mutational processes in human cancer
Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio.
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.
Marco Gerlinger;Andrew J. Rowan;Stuart Horswell;James Larkin.
The New England Journal of Medicine (2012)
Patterns of somatic mutation in human cancer genomes
Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh.
Genomic Classification and Prognosis in Acute Myeloid Leukemia
Elli Papaemmanuil;Moritz Gerstung;Lars Bullinger;Verena I Gaidzik.
The New England Journal of Medicine (2016)
Systematic identification of genomic markers of drug sensitivity in cancer cells
Mathew J. Garnett;Elena J. Edelman;Sonja J. Heidorn;Christopher Greenman;Christopher Greenman.
Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
Philip J. Stephens;Chris D. Greenman;Beiyuan Fu;Fengtang Yang.
A comprehensive catalogue of somatic mutations from a human cancer genome
Erin D. Pleasance;R. Keira Cheetham;Philip J. Stephens;David J. Mcbride.
Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
J. Nangalia;C.E. Massie;E.J. Baxter;F.L. Nice.
The New England Journal of Medicine (2013)
Mutational Processes Molding the Genomes of 21 Breast Cancers
Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo.
The landscape of cancer genes and mutational processes in breast cancer
Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo.
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