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Genetics

D-Index
54
Citations
59626
World Ranking
3600
National Ranking
426

Overview

Andrew Menzies is affiliated with the Wellcome Sanger Institute in the United Kingdom. Their research spans primarily the field of Earth and Planetary Sciences, with significant contributions in subfields including Geophysics, Artificial Intelligence, Cancer Research, Molecular Biology, and Biomedical Engineering.

The topics central to Menzies's work include Geological and Geochemical Analysis, Geochemistry and Geologic Mapping, Cancer Genomics and Diagnostics, earthquake and tectonic studies, Acute Myeloid Leukemia Research, Mineralogy and Gemology Studies, and Metal Extraction and Bioleaching.

Menzies has published extensively, with frequent appearances in the venues Microscopy and Microanalysis, Journal of Volcanology and Geothermal Research, Nature, bioRxiv (Cold Spring Harbor Laboratory), and Nature Communications.

Representative recent papers authored or coauthored by Menzies include:

  • Tobacco smoking and somatic mutations in human bronchial epithelium, 2020, Nature
  • The mutational landscape of human somatic and germline cells, 2021, Nature
  • Extensive heterogeneity in somatic mutation and selection in the human bladder, 2020, Science
  • Life histories of myeloproliferative neoplasms inferred from phylogenies., 2022, Apollo (University of Cambridge)
  • Tourmaline as a Tracer of Late-Magmatic to Hydrothermal Fluid Evolution: The World-Class San Rafael Tin (-Copper) Deposit, Peru, 2020, Economic Geology

Frequent collaborators include Peter J. Campbell, Tim Coorens, Luiza Moore, Iñigo Martincorena, and Kevin J. Dawson.

Best Publications

  • Mutations of the BRAF gene in human cancer

    Helen Davies;Graham R. Bignell;Charles Cox;Philip Stephens

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer.

    Simon A. Forbes;Nidhi Bindal;Sally Bamford;Charlotte Cole

  • Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

    Philip J. Stephens;Chris D. Greenman;Beiyuan Fu;Fengtang Yang

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Mutational Processes Molding the Genomes of 21 Breast Cancers

    Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • A comprehensive catalogue of somatic mutations from a human cancer genome

    Erin D. Pleasance;R. Keira Cheetham;Philip J. Stephens;David J. Mcbride

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

    Ignacio Varela;Patrick Tarpey;Keiran Raine;Dachuan Huang

  • High burden and pervasive positive selection of somatic mutations in normal human skin

    Iñigo Martincorena;Amit Roshan;Moritz Gerstung;Peter Ellis

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

  • The patterns and dynamics of genomic instability in metastatic pancreatic cancer

    Peter J. Campbell;Peter J. Campbell;Shinichi Yachida;Laura J. Mudie;Philip J. Stephens

  • Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

    Gillian L. Dalgliesh;Kyle Furge;Chris Greenman;Lina Chen

  • A small-cell lung cancer genome with complex signatures of tobacco exposure

    Erin D. Pleasance;Philip J. Stephens;Sarah O’Meara;Sarah O’Meara;David J. McBride

  • Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

    Peter J Campbell;Philip J Stephens;Erin D Pleasance;Sarah O'Meara

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

    Gijs Van Haaften;Gillian L Dalgliesh;Helen Davies;Lina Chen

  • Subclonal diversification of primary breast cancer revealed by multiregion sequencing

    Lucy R. Yates;Moritz Gerstung;Stian Knappskog;Christine Desmedt

  • The Catalogue of Somatic Mutations in Cancer (COSMIC).

    S.A. Forbes;G. Bhamra;S. Bamford;E. Dawson

Frequent Co-Authors

Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Jon W. Teague
Jon W. Teague Wellcome Sanger Institute
Adam Butler
Adam Butler Wellcome Sanger Institute
P. Andrew Futreal
P. Andrew Futreal The University of Texas MD Anderson Cancer Center
Keiran Raine
Keiran Raine Wellcome Sanger Institute
Peter Van Loo
Peter Van Loo The Francis Crick Institute
David T. Jones
David T. Jones University College London
Helen Davies
Helen Davies University of Cambridge
Serena Nik-Zainal
Serena Nik-Zainal University of Cambridge

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