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Genetics

D-Index
58
Citations
67282
World Ranking
3273
National Ranking
398

Overview

Keiran Raine is affiliated with the Wellcome Sanger Institute in the United Kingdom. Their research spans multiple fields of study, primarily focusing on biochemistry, genetics, and molecular biology, with significant contributions to medicine.

Their work covers various subfields including molecular biology, cancer research, plant science, surgery, and epidemiology. The main topics of their research include:

  • Genomics and Phylogenetic Studies
  • Cancer Genomics and Diagnostics
  • Chromosomal and Genetic Variations
  • FOXO Transcription Factor Regulation
  • Cancer-Related Gene Regulation
  • CRISPR and Genetic Engineering
  • Nephrotoxicity and Medicinal Plants

Keiran Raine's frequent co-authors include:

  • Peter J. Campbell
  • Adam P. Butler
  • Iñigo Martincorena
  • Jonas Demeulemeester
  • Sonia Zumalave

Their publication record includes papers published in venues such as:

  • Nature Biotechnology
  • Nature Genetics
  • Nature Communications
  • Science
  • Nature

Notable recent papers authored or co-authored by Keiran Raine include:

  • Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition, 2020, Nature Genetics
  • Extensive heterogeneity in somatic mutation and selection in the human bladder, 2020, Science
  • Convergent somatic mutations in metabolism genes in chronic liver disease, 2021, Nature
  • Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture, 2021, Nature Communications
  • Framework for quality assessment of whole genome cancer sequences, 2020, Nature Communications

Best Publications

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.

    Marco Gerlinger;Andrew J. Rowan;Stuart Horswell;James Larkin

  • Genomic Classification and Prognosis in Acute Myeloid Leukemia

    Elli Papaemmanuil;Moritz Gerstung;Lars Bullinger;Verena I Gaidzik

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

    J. Nangalia;C.E. Massie;E.J. Baxter;F.L. Nice

  • Mutational Processes Molding the Genomes of 21 Breast Cancers

    Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • Clinical and biological implications of driver mutations in myelodysplastic syndromes.

    Elli Papaemmanuil;Moritz Gerstung;Luca Malcovati;Sudhir Tauro

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

    Xose S. Puente;Magda Pinyol;Víctor Quesada;Laura Conde

  • Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

    Ignacio Varela;Patrick Tarpey;Keiran Raine;Dachuan Huang

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

  • Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts

    E. Papaemmanuil;M. Cazzola;J. Boultwood;L. Malcovati

  • Universal Patterns of Selection in Cancer and Somatic Tissues

    Iñigo Martincorena;Keiran M. Raine;Moritz Gerstung;Kevin J. Dawson

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

    Helen Davies;Dominik D. Glodzik;Sandro S. Morganella;Lucy R. Yates

  • Subclonal diversification of primary breast cancer revealed by multiregion sequencing

    Lucy R. Yates;Moritz Gerstung;Stian Knappskog;Christine Desmedt

  • Lung cancer: intragenic ERBB2 kinase mutations in tumours.

    Philip Stephens;Chris Hunter;Graham Bignell;Sarah Edkins

  • Prediction of acute myeloid leukaemia risk in healthy individuals

    Sagi Abelson;Grace Collord;Grace Collord;Stanley W.K. Ng;Omer Weissbrod

Frequent Co-Authors

Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Jon W. Teague
Jon W. Teague Wellcome Sanger Institute
Peter Van Loo
Peter Van Loo The Francis Crick Institute
Adam Butler
Adam Butler Wellcome Sanger Institute
Andrew Menzies
Andrew Menzies Wellcome Sanger Institute
David C. Wedge
David C. Wedge University of Manchester
David T. Jones
David T. Jones University College London
Patrick S. Tarpey
Patrick S. Tarpey Wellcome Sanger Institute
Serena Nik-Zainal
Serena Nik-Zainal University of Cambridge

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