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Medicine

D-Index
152
Citations
119630
World Ranking
1060
National Ranking
112

Overview

Carlos Caldas is affiliated with the University of Cambridge in the United Kingdom. Their primary research interests lie within the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. The scientist's work focuses extensively on Molecular Biology, Cancer Research, Oncology, Pulmonary and Respiratory Medicine, and Genetics.

The main topics covered in their research include:

  • Cancer Genomics and Diagnostics
  • Cancer Cells and Metastasis
  • Single-cell and spatial transcriptomics
  • Breast Cancer Treatment Studies
  • Cancer Immunotherapy and Biomarkers
  • Genetic factors in colorectal cancer
  • Advanced Breast Cancer Therapies

Their recent publications feature studies published in high-impact journals, illustrating diverse aspects of cancer biology and therapy. Key recent papers include:

  • Multi-omic machine learning predictor of breast cancer therapy response, 2021, Nature
  • Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems, 2021, Science
  • Caring for patients with cancer in the COVID-19 era, 2020, Nature Medicine
  • Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer, 2020, Nature Cancer
  • Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4+ and PDPN+ CAFs to clinical outcome, 2020, Nature Cancer

Carlos Caldas frequently collaborates with other researchers. Notable co-authors include Oscar M. Rueda, Suet-Feung Chin, Alejandra Bruna, Stephen-John Sammut, and Elena Provenzano.

Their work is published in several prominent venues, with multiple publications appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Nature Cancer
  • Breast Cancer Research

Beyond journal articles, Carlos Caldas has contributed to book publications as well. A recent book titled SAÚDE DA MULHER E OBSTETRÍCIA: DO ENSINO À ASSISTÊNCIA was published in 2024 by Editora Humanize eBooks.

Best Publications

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

    Christina Curtis;Christina Curtis;Sohrab P Shah;Suet-Feung Chin;Gulisa Turashvili

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

    Sarah-Jane Dawson;Dana W Y Tsui;Muhammed Murtaza;Heather Biggs

  • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

    Mario F Fraga;Esteban Ballestar;Ana Villar-Garea;Manuel Boix-Chornet

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • The clonal and mutational evolution spectrum of primary triple-negative breast cancers

    Sohrab P. Shah;Andrew Roth;Rodrigo Goya;Arusha Oloumi

  • Liquid biopsies come of age: towards implementation of circulating tumour DNA

    Jonathan C. M. Wan;Charles E. Massie;Javier Garcia-Corbacho;Florent Mouliere

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

    Muhammed Murtaza;Sarah-Jane Dawson;Dana W. Y. Tsui;Davina Gale

  • Patient-derived xenograft models: an emerging platform for translational cancer research.

    Manuel Hidalgo;Frederic Amant;Andrew V. Biankin;Eva Budinská

  • The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes

    Bernard Pereira;Suet Feung Chin;Oscar M. Rueda;Hans Kristian Moen Vollan

  • Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma.

    C Caldas;S A Hahn;L T da Costa;M S Redston

  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

    Fiona M. Blows;Kristy E. Driver;Marjanka K. Schmidt;Annegien Broeks

  • Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA

    Tim Forshew;Muhammed Murtaza;Christine Parkinson;Christine Parkinson;Davina Gale

  • Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

    Sohrab P. Shah;Ryan D. Morin;Jaswinder Khattra;Leah Prentice

  • Molecular Classification and Molecular Forecasting of Breast Cancer: Ready for Clinical Application?

    James D. Brenton;Lisa A. Carey;Ahmed Ashour Ahmed;Carlos Caldas

  • MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype

    Cherie Blenkiron;Leonard D Goldstein;Natalie P Thorne;Inmaculada Spiteri

  • Genetic Unmasking of an Epigenetically Silenced microRNA in Human Cancer Cells

    Amaia Lujambio;Santiago Ropero;Esteban Ballestar;Mario F. Fraga

Frequent Co-Authors

Suet-Feung Chin
Suet-Feung Chin University of Cambridge
Paul D.P. Pharoah
Paul D.P. Pharoah University of Cambridge
Samuel Aparicio
Samuel Aparicio University of British Columbia
Ian O. Ellis
Ian O. Ellis University of Nottingham
Anne Lise Børresen-Dale
Anne Lise Børresen-Dale Oslo University Hospital
Rebecca C. Fitzgerald
Rebecca C. Fitzgerald University of Cambridge
James D. Brenton
James D. Brenton University of Cambridge
Andrew E. Teschendorff
Andrew E. Teschendorff University College London
Andrew R. Green
Andrew R. Green University of Nottingham
Christina Curtis
Christina Curtis Stanford University

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