World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
79
Citations
57378
World Ranking
1604
National Ranking
207

David C. Wedge publication distribution in Genetics in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Genetics in 2026. The highlighted bar marks where David C. Wedge sits on this spectrum.

45–54 publications: 6 scientists 55–64 publications: 10 scientists 65–74 publications: 35 scientists 75–84 publications: 84 scientists 85–94 publications: 102 scientists 95–104 publications: 151 scientists 105–114 publications: 175 scientists 115–124 publications: 203 scientists 125–134 publications: 217 scientists 135–144 publications: 205 scientists 145–154 publications: 193 scientists 155–164 publications: 188 scientists 165–174 publications: 170 scientists 175–184 publications: 178 scientists 185–194 publications: 164 scientists 195–204 publications: 173 scientists 205–214 publications: 159 scientists 215–224 publications: 134 scientists 225–234 publications: 143 scientists 235–244 publications: 105 scientists 245–254 publications: 114 scientists 255–264 publications: 92 scientists 265–274 publications: 88 scientists 275–284 publications: 87 scientists 285–294 publications: 80 scientists 295–304 publications: 62 scientists 305–314 publications: 75 scientists 315–324 publications: 67 scientists 325–334 publications: 60 scientists 335–344 publications: 52 scientists 345–354 publications: 40 scientists 355–364 publications: 48 scientists 365–374 publications: 47 scientists 375–384 publications: 46 scientists 385–394 publications: 31 scientists 395–404 publications: 27 scientists 405–414 publications: 40 scientists 415–424 publications: 30 scientists 425–434 publications: 43 scientists 435–444 publications: 29 scientists 445–454 publications: 14 scientists 455–464 publications: 28 scientists 465–474 publications: 21 scientists 475–484 publications: 21 scientists 485–494 publications: 22 scientists 495–504 publications: 17 scientists 505–514 publications: 12 scientists 515–524 publications: 11 scientists 525–534 publications: 8 scientists 535–544 publications: 8 scientists 545–554 publications: 14 scientists 555–564 publications: 4 scientists 565–574 publications: 11 scientists 575–584 publications: 5 scientists 585–594 publications: 11 scientists 595–604 publications: 12 scientists 605–614 publications: 7 scientists 615–624 publications: 6 scientists 625–634 publications: 10 scientists 635–644 publications: 9 scientists 645–654 publications: 10 scientists 655–664 publications: 6 scientists 665–674 publications: 6 scientists 675–684 publications: 6 scientists 685–694 publications: 4 scientists 695–702 publications: 6 scientists 703+ publications: 100 scientists
45 publications 703+

This scientist: 231 publications — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 703 publications or more.

David C. Wedge D-index placement in Genetics in 2026

The chart shows the D-index (discipline H-index) distribution of Genetics scientists ranked by Research.com in 2026. The highlighted bar marks where David C. Wedge sits on this spectrum.

40–41 D-Index: 24 scientists 42–43 D-Index: 52 scientists 44–45 D-Index: 84 scientists 46–47 D-Index: 112 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 141 scientists 52–53 D-Index: 143 scientists 54–55 D-Index: 145 scientists 56–57 D-Index: 179 scientists 58–59 D-Index: 162 scientists 60–61 D-Index: 175 scientists 62–63 D-Index: 191 scientists 64–65 D-Index: 172 scientists 66–67 D-Index: 184 scientists 68–69 D-Index: 164 scientists 70–71 D-Index: 158 scientists 72–73 D-Index: 150 scientists 74–75 D-Index: 136 scientists 76–77 D-Index: 127 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 111 scientists 82–83 D-Index: 110 scientists 84–85 D-Index: 110 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 102 scientists 90–91 D-Index: 66 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 70 scientists 96–97 D-Index: 54 scientists 98–99 D-Index: 60 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 55 scientists 104–105 D-Index: 45 scientists 106–107 D-Index: 42 scientists 108–109 D-Index: 28 scientists 110–111 D-Index: 39 scientists 112–113 D-Index: 25 scientists 114–115 D-Index: 31 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 34 scientists 120–121 D-Index: 29 scientists 122–123 D-Index: 29 scientists 124–125 D-Index: 18 scientists 126–127 D-Index: 27 scientists 128–129 D-Index: 22 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 11 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 12 scientists 138–139 D-Index: 21 scientists 140–141 D-Index: 4 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 14 scientists 146–147 D-Index: 6 scientists 148–149 D-Index: 10 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 9 scientists 154–155 D-Index: 8 scientists 156–157 D-Index: 8 scientists 158–159 D-Index: 9 scientists 160+ D-Index: 96 scientists
40 D-Index 160+

This scientist: 79 D-Index — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 160 D-Index or more.

Overview

David C. Wedge is affiliated with the University of Manchester in the United Kingdom. Their research spans several interconnected fields within biochemistry, genetics, molecular biology, and medicine, with a particular focus on cancer genomics and diagnostics.

The scientist's recent publications address a range of topics related to cancer genetics and tumor biology. Notable papers include:

  • Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes, 2021, Cell
  • Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition, 2020, Nature Genetics
  • Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor, 2022, Cell Genomics
  • Promises and challenges of adoptive T-cell therapies for solid tumours, 2021, British Journal of Cancer
  • Genomic and evolutionary classification of lung cancer in never smokers, 2021, Nature Genetics

Wedge frequently collaborates with other researchers in their field. Their most common co-authors include:

  • Ludmil B. Alexandrov
  • Peter Van Loo
  • Tongwu Zhang
  • Andreas Gruber
  • Stefan C. Dentro

The scientist has published extensively in several major venues relevant to genetics and cancer research. Their frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cancer Research
  • Nature Genetics
  • Nature

Their primary fields of study are biochemistry, genetics, and molecular biology, as well as medicine. These broad areas break down into specific subfields that frame much of their research:

  • Molecular Biology
  • Cancer Research
  • Pulmonary and Respiratory Medicine
  • Genetics
  • Oncology

The main topics covered across their publications focus predominantly on cancer and include:

  • Cancer Genomics and Diagnostics
  • Genetic factors in colorectal cancer
  • Epigenetics and DNA Methylation
  • Prostate Cancer Treatment and Research
  • RNA modifications and cancer
  • Prostate Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations

Best Publications

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

    J. Nangalia;C.E. Massie;E.J. Baxter;F.L. Nice

  • Mutational Processes Molding the Genomes of 21 Breast Cancers

    Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • Clinical and biological implications of driver mutations in myelodysplastic syndromes.

    Elli Papaemmanuil;Moritz Gerstung;Luca Malcovati;Sudhir Tauro

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • High burden and pervasive positive selection of somatic mutations in normal human skin

    Iñigo Martincorena;Amit Roshan;Moritz Gerstung;Peter Ellis

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

  • The evolutionary history of lethal metastatic prostate cancer.

    Gunes Gundem;Peter Van Loo;Peter Van Loo;Peter Van Loo;Barbara Kremeyer;Ludmil B. Alexandrov

  • Deciphering Signatures of Mutational Processes Operative in Human Cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;David C. Wedge;Peter J. Campbell;Peter J. Campbell

  • Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

    Elza C. de Bruin;Nicholas McGranahan;Nicholas McGranahan;Richard Mitter;Max Salm

  • Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

    Jianjun Zhang;Junya Fujimoto;Jianhua Zhang;David C. Wedge

  • The evolutionary history of 2,658 cancers

    Moritz Gerstung;Moritz Gerstung;Clemency Jolly;Ignaty Leshchiner;Stefan C Dentro;Stefan C Dentro;Stefan C Dentro

  • Clock-like mutational processes in human somatic cells

    Ludmil B Alexandrov;Philip H Jones;Philip H Jones;David C Wedge;Julian E Sale

  • Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

    Niccolo Bolli;Hervé Avet-Loiseau;David C. Wedge;Peter Van Loo

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Subclonal diversification of primary breast cancer revealed by multiregion sequencing

    Lucy R. Yates;Moritz Gerstung;Stian Knappskog;Christine Desmedt

  • Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.

    Sam Behjati;Sam Behjati;Patrick S Tarpey;Nadège Presneau;Susanne Scheipl;Susanne Scheipl

  • Genomic Evolution of Breast Cancer Metastasis and Relapse

    Lucy R. Yates;Stian Knappskog;Stian Knappskog;David Wedge;David Wedge;James H.R. Farmery

Frequent Co-Authors

Peter Van Loo
Peter Van Loo The Francis Crick Institute
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Ludmil B. Alexandrov
Ludmil B. Alexandrov University of California, San Diego
Moritz Gerstung
Moritz Gerstung German Cancer Research Center
Keiran Raine
Keiran Raine Wellcome Sanger Institute
Anne Lise Børresen-Dale
Anne Lise Børresen-Dale Oslo University Hospital
Jon W. Teague
Jon W. Teague Wellcome Sanger Institute
Inigo Martincorena
Inigo Martincorena Wellcome Sanger Institute
Adam Butler
Adam Butler Wellcome Sanger Institute

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