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Medicine

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170
Citations
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World Ranking
521
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Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Nikhil C. Munshi is affiliated with Harvard University in the United States and conducts research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Hematology, Molecular Biology, Oncology, Immunology, and Cancer Research. The main research topics focus on Multiple Myeloma Research and Treatments, Protein Degradation and Inhibitors, CAR-T cell therapy research, Peptidase Inhibition and Analysis, Chronic Lymphocytic Leukemia Research, Immunotherapy and Immune Responses, and Ubiquitin and proteasome pathways.

The scientist has contributed to numerous papers with a significant impact within their field. Notable recent papers include:

  • Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma, 2021, New England Journal of Medicine
  • Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study, 2021, The Lancet
  • Ciltacabtagene Autoleucel, an Anti-B-cell Maturation Antigen Chimeric Antigen Receptor T-Cell Therapy, for Relapsed/Refractory Multiple Myeloma: CARTITUDE-1 2-Year Follow-Up, 2022, Journal of Clinical Oncology
  • Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma, 2022, New England Journal of Medicine
  • A large meta-analysis establishes the role of MRD negativity in long-term survival outcomes in patients with multiple myeloma, 2020, Blood Advances

Munshi frequently collaborates with other researchers, including Kenneth C. Anderson, Mehmet Samur, Mariateresa Fulciniti, Paul G. Richardson, and Eugenio Morelli. These collaborations reflect a consistent engagement within a specialized research community focused on hematology and oncology.

The scientist's work appears regularly in prominent publication venues, with a notable number of publications in Blood, Clinical Lymphoma Myeloma & Leukemia, Journal of Clinical Oncology, Blood Advances, and Leukemia. This distribution of publications indicates a focused contribution to journals specializing in blood diseases and cancer research.

Recognition of the scientist's professional standing includes membership in the Association of American Physicians, highlighting a position in a network of medical researchers.

Best Publications

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Antitumor activity of thalidomide in refractory multiple myeloma.

    S Singhal;J Mehta;R Desikan;D Ayers

  • International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma

    Shaji Kumar;Bruno Paiva;Kenneth C. Anderson;Brian Durie

  • Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer.

    Robert C. Flanigan;Sydney E. Salmon;Brent A. Blumenstein;Scott I. Bearman

  • Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma

    Noopur Raje;Jesus Berdeja;Yi Lin;David Siegel

  • Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells

    Jan Krönke;Namrata D. Udeshi;Anupama Narla;Peter Grauman

  • Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma

    Nikhil C Munshi;Larry D Anderson;Nina Shah;Deepu Madduri

  • Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts

    E. Papaemmanuil;M. Cazzola;J. Boultwood;L. Malcovati

  • NF-κB as a Therapeutic Target in Multiple Myeloma *

    Teru Hideshima;Dharminder Chauhan;Paul Richardson;Constantine Mitsiades

  • Lenalidomide, Bortezomib, and Dexamethasone with Transplantation for Myeloma

    Michel Attal;Valerie Lauwers-Cances;Cyrille Hulin;Xavier Leleu

  • Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1

    S. Vincent Rajkumar;Jean Luc Harousseau;Brian Durie;Kenneth C. Anderson

  • Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study

    Jesus G Berdeja;Deepu Madduri;Saad Z Usmani;Andrzej Jakubowiak

  • Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma.

    Paul G. Richardson;Edie Weller;Sagar Lonial;Andrzej J. Jakubowiak

  • Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

    Niccolo Bolli;Hervé Avet-Loiseau;David C. Wedge;Peter Van Loo

  • Molecular sequelae of proteasome inhibition in human multiple myeloma cells

    Nicholas Mitsiades;Constantine S. Mitsiades;Vassiliki Poulaki;Dharminder Chauhan

  • The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications.

    Nicholas Mitsiades;Constantine S. Mitsiades;Paul G. Richardson;Vassiliki Poulaki

  • Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications

    Nicholas Mitsiades;Constantine S. Mitsiades;Vassiliki Poulaki;Dharminder Chauhan

  • Graft-versus-myeloma effect: proof of principle

    Guido Tricot;David H. Vesole;Sundar Jagannath;Jennifer Hilton

  • Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.

    Teru Hideshima;Constantine Mitsiades;Masaharu Akiyama;Toshiaki Hayashi

  • Total Therapy With Tandem Transplants for Newly Diagnosed Multiple Myeloma

    B. Barlogie;S. Jagannath;K.R. Desikan;S. Mattox

Frequent Co-Authors

Kenneth C. Anderson
Kenneth C. Anderson Harvard University
Paul G. Richardson
Paul G. Richardson Harvard University
Teru Hideshima
Teru Hideshima Harvard University
Yu-Tzu Tai
Yu-Tzu Tai Harvard University
Dharminder Chauhan
Dharminder Chauhan Harvard University
Noopur Raje
Noopur Raje Harvard University
Constantine S. Mitsiades
Constantine S. Mitsiades Harvard University
Robert L. Schlossman
Robert L. Schlossman Harvard University
Pierfrancesco Tassone
Pierfrancesco Tassone Magna Graecia University

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