Dharminder Chauhan mainly investigates Cancer research, Bone marrow, Proteasome inhibitor, Multiple myeloma and Bortezomib. His work deals with themes such as Cell culture, Cell growth, Apoptosis, Immunology and Histone deacetylase, which intersect with Cancer research. His Cell culture research incorporates elements of Cell and Cytotoxicity.
His research in Bone marrow intersects with topics in Natural killer cell and Stromal cell. Dharminder Chauhan combines subjects such as Retinoblastoma, Leukemia and Pharmacology with his study of Multiple myeloma. His study in Bortezomib is interdisciplinary in nature, drawing from both Ubiquitin, Cancer cell, IκBα, Proteasome and IκB kinase.
Dharminder Chauhan spends much of his time researching Cancer research, Bortezomib, Multiple myeloma, Bone marrow and Cell culture. His Cancer research study incorporates themes from Immunology, Apoptosis, Cell growth and Cytotoxicity. In his research, Gene expression is intimately related to Molecular biology, which falls under the overarching field of Apoptosis.
His Bortezomib study combines topics from a wide range of disciplines, such as Proteasome inhibitor, Proteasome, Cancer cell, Pharmacology and In vivo. The concepts of his Multiple myeloma study are interwoven with issues in Immune system and Dexamethasone. His Bone marrow study integrates concerns from other disciplines, such as Peripheral blood mononuclear cell, Angiogenesis and CD40.
His main research concerns Cancer research, Multiple myeloma, Bortezomib, Ubiquitin and Cancer cell. His research integrates issues of Cell culture, Cell growth and Immune system, Immunology, Bone marrow in his study of Cancer research. He has included themes like CD40, Tumor microenvironment, Immunogenic cell death, Stem cell and Cytotoxicity in his Multiple myeloma study.
His Bortezomib research is multidisciplinary, relying on both Proteasome inhibitor and Proteasome. The various areas that Dharminder Chauhan examines in his Ubiquitin study include Receptor and Cell biology. His Pomalidomide research focuses on Pharmacology and how it relates to Apoptosis.
His primary areas of investigation include Cancer research, Multiple myeloma, Bortezomib, Proteasome and Pomalidomide. His work carried out in the field of Cancer research brings together such families of science as DNA damage, Apoptosis, Histone deacetylase, DNA repair and Kinase. His Multiple myeloma research includes elements of Immune system, Immunity, Bone marrow and Cytotoxicity.
His studies in Bortezomib integrate themes in fields like Proteasome inhibitor, Cell growth and Pharmacology. His work focuses on many connections between Cell growth and other disciplines, such as Immunology, that overlap with his field of interest in Nicotinamide phosphoribosyltransferase. His biological study spans a wide range of topics, including Enzyme activator and Caspase.
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The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.
Teru Hideshima;Paul Richardson;Dharminder Chauhan;Vito J. Palombella.
Cancer Research (2001)
Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy.
Teru Hideshima;Dharminder Chauhan;Dharminder Chauhan;Yoshihito Shima;Yoshihito Shima;Noopur Raje;Noopur Raje.
Blood (2000)
NF-κB as a Therapeutic Target in Multiple Myeloma *
Teru Hideshima;Dharminder Chauhan;Paul Richardson;Constantine Mitsiades.
Journal of Biological Chemistry (2002)
Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma.
Faith E. Davies;Faith E. Davies;Faith E. Davies;Noopur Raje;Noopur Raje;Noopur Raje;Teru Hideshima;Teru Hideshima;Teru Hideshima;Suzanne Lentzsch;Suzanne Lentzsch;Suzanne Lentzsch.
Blood (2001)
Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
Paul G. Richardson;Robert L. Schlossman;Robert L. Schlossman;Edie Weller;Edie Weller;Teru Hideshima;Teru Hideshima.
Blood (2002)
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications.
Nicholas Mitsiades;Constantine S. Mitsiades;Paul G. Richardson;Vassiliki Poulaki.
Blood (2003)
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
Nicholas Mitsiades;Constantine S. Mitsiades;Vassiliki Poulaki;Dharminder Chauhan.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications.
D Gupta;S P Treon;Y Shima;T Hideshima.
Leukemia (2001)
A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib
Dharminder Chauhan;Laurence Catley;Guilan Li;Klaus Podar.
Cancer Cell (2005)
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications
Nicholas Mitsiades;Constantine S. Mitsiades;Vassiliki Poulaki;Dharminder Chauhan.
Blood (2002)
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