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Genetics

D-Index
88
Citations
60566
World Ranking
1139
National Ranking
545

Research.com Recognitions

  • 2018 - Fellow of Alfred P. Sloan Foundation

Overview

Ludmil B. Alexandrov is affiliated with the University of California, San Diego in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, along with Medicine. Within these main domains, their work extends into the subfields of Molecular Biology, Cancer Research, Oncology, Genetics, and Pulmonary and Respiratory Medicine.

The scientist's research topics focus heavily on Cancer Genomics and Diagnostics, along with Genetic factors in colorectal cancer, Epigenetics and DNA Methylation, Genomics and Phylogenetic Studies, Genomics and Rare Diseases, DNA Repair Mechanisms, and Genomic variations and chromosomal abnormalities.

Among their recent papers are:

  • The repertoire of mutational signatures in human cancer, 2020, Nature
  • Pan-cancer analysis of whole genomes, 2020, Nature
  • Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing, 2020, Nature Genetics
  • Comprehensive molecular characterization of mitochondrial genomes in human cancers, 2020, Nature Genetics
  • Signatures of copy number alterations in human cancer, 2022, Nature

Frequently collaborating with Ludmil B. Alexandrov are:

  • Erik N. Bergstrom
  • Marcos Díaz-Gay
  • Azhar Khandekar
  • David J. Adams
  • David C. Wedge

Publications by this researcher are commonly found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Nature
  • Nature Genetics

In recognition of their scientific contributions, Ludmil B. Alexandrov was awarded the title of Fellow of the Alfred P. Sloan Foundation in 2018.

Best Publications

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • The Repertoire of Mutational Signatures in Human Cancer

    Ludmil B Alexandrov;Jaegil Kim;Nicholas J Haradhvala;Nicholas J Haradhvala;Mi Ni Huang

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Mutational Processes Molding the Genomes of 21 Breast Cancers

    Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • High burden and pervasive positive selection of somatic mutations in normal human skin

    Iñigo Martincorena;Amit Roshan;Moritz Gerstung;Peter Ellis

  • Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

    Kornelius Schulze;Sandrine Imbeaud;Eric Letouzé;Ludmil B. Alexandrov;Ludmil B. Alexandrov

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

  • Whole-genome landscapes of major melanoma subtypes

    Nicholas K. Hayward;Nicholas K. Hayward;James S. Wilmott;Nicola Waddell;Nicola Waddell;Peter A. Johansson

  • The evolutionary history of lethal metastatic prostate cancer.

    Gunes Gundem;Peter Van Loo;Peter Van Loo;Peter Van Loo;Barbara Kremeyer;Ludmil B. Alexandrov

  • Deciphering Signatures of Mutational Processes Operative in Human Cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;David C. Wedge;Peter J. Campbell;Peter J. Campbell

  • Mutational signatures associated with tobacco smoking in human cancer

    Ludmil B Alexandrov;Ludmil B Alexandrov;Young Seok Ju;Kerstin Haase;Peter Van Loo;Peter Van Loo

  • Clock-like mutational processes in human somatic cells

    Ludmil B Alexandrov;Philip H Jones;Philip H Jones;David C Wedge;Julian E Sale

  • Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

    Niccolo Bolli;Hervé Avet-Loiseau;David C. Wedge;Peter Van Loo

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

    Xiaotu Ma;Yu Liu;Yanling Liu;Ludmil B. Alexandrov

  • Timing, rates and spectra of human germline mutation

    Raheleh Rahbari;Arthur Wuster;Sarah J Lindsay;Robert J Hardwick

  • Subclonal diversification of primary breast cancer revealed by multiregion sequencing

    Lucy R. Yates;Moritz Gerstung;Stian Knappskog;Christine Desmedt

  • Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma

    Apinya Jusakul;Apinya Jusakul;Ioana Cutcutache;Chern Han Yong;Jing Quan Lim

  • Genomic Evolution of Breast Cancer Metastasis and Relapse

    Lucy R. Yates;Stian Knappskog;Stian Knappskog;David Wedge;David Wedge;James H.R. Farmery

Frequent Co-Authors

Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
David C. Wedge
David C. Wedge University of Manchester
Peter Van Loo
Peter Van Loo The Francis Crick Institute
Serena Nik-Zainal
Serena Nik-Zainal University of Cambridge
Inigo Martincorena
Inigo Martincorena Wellcome Sanger Institute
Ultan McDermott
Ultan McDermott AstraZeneca (United Kingdom)
Anne Lise Børresen-Dale
Anne Lise Børresen-Dale Oslo University Hospital
Andrea L. Richardson
Andrea L. Richardson Johns Hopkins University
Jon W. Teague
Jon W. Teague Wellcome Sanger Institute

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