World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
90
Citations
24022
World Ranking
1080
National Ranking
519

Edward H. Schuchman publication distribution in Genetics in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Genetics in 2026. The highlighted bar marks where Edward H. Schuchman sits on this spectrum.

45–54 publications: 6 scientists 55–64 publications: 10 scientists 65–74 publications: 35 scientists 75–84 publications: 84 scientists 85–94 publications: 102 scientists 95–104 publications: 151 scientists 105–114 publications: 175 scientists 115–124 publications: 203 scientists 125–134 publications: 217 scientists 135–144 publications: 205 scientists 145–154 publications: 193 scientists 155–164 publications: 188 scientists 165–174 publications: 170 scientists 175–184 publications: 178 scientists 185–194 publications: 164 scientists 195–204 publications: 173 scientists 205–214 publications: 159 scientists 215–224 publications: 134 scientists 225–234 publications: 143 scientists 235–244 publications: 105 scientists 245–254 publications: 114 scientists 255–264 publications: 92 scientists 265–274 publications: 88 scientists 275–284 publications: 87 scientists 285–294 publications: 80 scientists 295–304 publications: 62 scientists 305–314 publications: 75 scientists 315–324 publications: 67 scientists 325–334 publications: 60 scientists 335–344 publications: 52 scientists 345–354 publications: 40 scientists 355–364 publications: 48 scientists 365–374 publications: 47 scientists 375–384 publications: 46 scientists 385–394 publications: 31 scientists 395–404 publications: 27 scientists 405–414 publications: 40 scientists 415–424 publications: 30 scientists 425–434 publications: 43 scientists 435–444 publications: 29 scientists 445–454 publications: 14 scientists 455–464 publications: 28 scientists 465–474 publications: 21 scientists 475–484 publications: 21 scientists 485–494 publications: 22 scientists 495–504 publications: 17 scientists 505–514 publications: 12 scientists 515–524 publications: 11 scientists 525–534 publications: 8 scientists 535–544 publications: 8 scientists 545–554 publications: 14 scientists 555–564 publications: 4 scientists 565–574 publications: 11 scientists 575–584 publications: 5 scientists 585–594 publications: 11 scientists 595–604 publications: 12 scientists 605–614 publications: 7 scientists 615–624 publications: 6 scientists 625–634 publications: 10 scientists 635–644 publications: 9 scientists 645–654 publications: 10 scientists 655–664 publications: 6 scientists 665–674 publications: 6 scientists 675–684 publications: 6 scientists 685–694 publications: 4 scientists 695–702 publications: 6 scientists 703+ publications: 100 scientists
45 publications 703+

This scientist: 290 publications — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 703 publications or more.

Edward H. Schuchman D-index placement in Genetics in 2026

The chart shows the D-index (discipline H-index) distribution of Genetics scientists ranked by Research.com in 2026. The highlighted bar marks where Edward H. Schuchman sits on this spectrum.

40–41 D-Index: 24 scientists 42–43 D-Index: 52 scientists 44–45 D-Index: 84 scientists 46–47 D-Index: 112 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 141 scientists 52–53 D-Index: 143 scientists 54–55 D-Index: 145 scientists 56–57 D-Index: 179 scientists 58–59 D-Index: 162 scientists 60–61 D-Index: 175 scientists 62–63 D-Index: 191 scientists 64–65 D-Index: 172 scientists 66–67 D-Index: 184 scientists 68–69 D-Index: 164 scientists 70–71 D-Index: 158 scientists 72–73 D-Index: 150 scientists 74–75 D-Index: 136 scientists 76–77 D-Index: 127 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 111 scientists 82–83 D-Index: 110 scientists 84–85 D-Index: 110 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 102 scientists 90–91 D-Index: 66 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 70 scientists 96–97 D-Index: 54 scientists 98–99 D-Index: 60 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 55 scientists 104–105 D-Index: 45 scientists 106–107 D-Index: 42 scientists 108–109 D-Index: 28 scientists 110–111 D-Index: 39 scientists 112–113 D-Index: 25 scientists 114–115 D-Index: 31 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 34 scientists 120–121 D-Index: 29 scientists 122–123 D-Index: 29 scientists 124–125 D-Index: 18 scientists 126–127 D-Index: 27 scientists 128–129 D-Index: 22 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 11 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 12 scientists 138–139 D-Index: 21 scientists 140–141 D-Index: 4 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 14 scientists 146–147 D-Index: 6 scientists 148–149 D-Index: 10 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 9 scientists 154–155 D-Index: 8 scientists 156–157 D-Index: 8 scientists 158–159 D-Index: 9 scientists 160+ D-Index: 96 scientists
40 D-Index 160+

This scientist: 90 D-Index — 76th percentile

76% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 160 D-Index or more.

Research.com Recognitions

  • 2020 - Fellow, National Academy of Inventors

Overview

Edward H. Schuchman is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research focuses primarily on various aspects of medicine and biochemistry, genetics, and molecular biology, with a total of 48 publications in medicine and 30 in biochemistry, genetics, and molecular biology.

The scientist's work spans several subfields of study, including physiology with 22 publications, molecular biology with 18, pulmonary and respiratory medicine with 7, cell biology with 5, and genetics with 4 publications. Their research covers multiple main topics such as lysosomal storage disorders research, which includes 30 publications, sphingolipid metabolism and signaling with 24, cellular transport and secretion with 8, autoimmune and inflammatory disorders research and neuroinflammation and neurodegeneration mechanisms each with 6, erythrocyte function and pathophysiology also with 6, and lipid membrane structure and behavior with another 6 publications.

Edward H. Schuchman has published extensively in several scientific venues. The most frequent places of publication include:

  • Molecular Genetics and Metabolism
  • Nature Communications
  • Orphanet Journal of Rare Diseases
  • Neurobiology of Disease
  • Molecular Metabolism

In collaboration, this researcher has worked frequently with a number of coauthors including María Dolores Ledesma (8 publications), Calogera M. Simonaro (7 publications), Min Hee Park (4 publications), Im-Sook Song (4 publications), and Min-Koo Choi (4 publications).

Recent papers by Edward H. Schuchman include:

  • Consensus clinical management guidelines for acid sphingomyelinase deficiency (Niemann-Pick disease types A, B and A/B), 2023, Orphanet Journal of Rare Diseases
  • N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer's disease, 2020, Nature Communications
  • Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes, 2020, Molecular Metabolism
  • Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis, 2020, American Journal of Respiratory and Critical Care Medicine
  • Discovery of a dual-action small molecule that improves neuropathological features of Alzheimer's disease mice, 2022, Proceedings of the National Academy of Sciences

Edward H. Schuchman received recognition as a Fellow of the National Academy of Inventors in 2020.

Best Publications

  • Acid Sphingomyelinase–Deficient Human Lymphoblasts and Mice Are Defective in Radiation-Induced Apoptosis

    Pino Santana;Louis A Peña;Adriana Haimovitz-Friedman;Seamus Martin

  • Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

    Emyr Lloyd-Evans;Anthony J Morgan;Xingxuan He;David A Smith

  • Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy.

    Yutaka Morita;Gloria I. Perez;Francois Paris;Silvia R. Miranda

  • Acid sphingomyelinase activity triggers microparticle release from glial cells.

    Fabio Bianco;Cristiana Perrotta;Luisa Novellino;Maura Francolini

  • Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers.

    Silvia Muro;Carmen Garnacho;Julie A Champion;John Leferovich

  • Neurofibromatosis type 2

    Ashok R Asthagiri;Dilys M Parry;John A Butman;H Jeffrey Kim

  • Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease.

    Kenichi Horinouchi;Shai Erlich;Daniel P. Perl;Klaus Ferlinz

  • Deregulation of sphingolipid metabolism in Alzheimer's disease

    Xingxuan He;Yu Huang;Bin Li;Cheng-Xing Gong

  • Lipopolysaccharide Induces Disseminated Endothelial Apoptosis Requiring Ceramide Generation

    Adriana Haimovitz-Friedman;Carlos Cordon-Cardo;Shariff Bayoumy;Mark Garzotto

  • Enzyme replacement and enhancement therapies: lessons from lysosomal disorders

    Robert J. Desnick;Edward H. Schuchman

  • Intracerebral Transplantation of Bone Marrow‐Derived Mesenchymal Stem Cells Reduces Amyloid‐Beta Deposition and Rescues Memory Deficits in Alzheimer's Disease Mice by Modulation of Immune Responses

    Jong Kil Lee;Hee Kyung Jin;Shogo Endo;Edward H. Schuchman

  • Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair.

    Christina Tam;Christina Tam;Vincent Idone;Cecilia Devlin;Maria Cecília D.C. Fernandes

  • Molecular Cloning and Characterization of a Full-length Complementary DNA Encoding Human Acid Ceramidase IDENTIFICATION OF THE FIRST MOLECULAR LESION CAUSING FARBER DISEASE

    Jürgen Koch;Sabine Gärtner;Chi-Ming Li;Lothar E. Quintern

  • Zn2+-stimulated Sphingomyelinase Is Secreted by Many Cell Types and Is a Product of the Acid Sphingomyelinase Gene

    Scott L. Schissel;Edward H. Schuchman;Kevin Jon Williams;Ira Tabas

  • Enzyme replacement therapy for lysosomal diseases: lessons from 20 years of experience and remaining challenges.

    R. J. Desnick;E. H. Schuchman

  • The pathogenesis and treatment of acid sphingomyelinase-deficient Niemann-Pick disease.

    Schuchman Eh

  • Human acid sphingomyelinase. Isolation, nucleotide sequence and expression of the full-length and alternatively spliced cDNAs.

    E.H. Schuchman;M. Suchi;T. Takahashi;K. Sandhoff

  • Purification, characterization, and biosynthesis of human acid ceramidase.

    Katussevani Bernardo;Robert Hurwitz;Thomas Zenk;Robert J. Desnick

  • Chapter 53 – Lysosomal Storage Diseases: Perspectives and Principles

    Edward H. Schuchman;Melissa P. Wasserstein

  • Acid sphingomyelinase activity triggers microparticle release from glial cells This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.Thislicensedoesnot permit commercial exploitation or the creation of derivative works without specific permission.

    Fabio Bianco;Cristiana Perrotta;Luisa Novellino;Maura Francolini

Frequent Co-Authors

Robert J. Desnick
Robert J. Desnick Icahn School of Medicine at Mount Sinai
Erich Gulbins
Erich Gulbins University of Duisburg-Essen
Shimon Gatt
Shimon Gatt Hebrew University of Jerusalem
Konrad Sandhoff
Konrad Sandhoff University of Bonn
Seng H. Cheng
Seng H. Cheng Pfizer (United States)
Ira Tabas
Ira Tabas Columbia University
Zvi Fuks
Zvi Fuks Memorial Sloan Kettering Cancer Center
Jeffrey A. Medin
Jeffrey A. Medin Medical College of Wisconsin
Anthony H. Futerman
Anthony H. Futerman Weizmann Institute of Science
Richard Kolesnick
Richard Kolesnick Memorial Sloan Kettering Cancer Center

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