D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 50 Citations 7,936 89 World Ranking 10207 National Ranking 4481

Overview

What is she best known for?

The fields of study she is best known for:

  • Enzyme
  • Gene
  • Cancer

Alicja Bielawska mainly focuses on Biochemistry, Ceramide, Sphingolipid, Ceramidase and Neutral Ceramidase. Her research on Biochemistry frequently connects to adjacent areas such as Molecular biology. Her work carried out in the field of Ceramide brings together such families of science as Protein phosphatase 2, Phosphatase, Saccharomyces cerevisiae, Enzyme activator and Cell biology.

Her research integrates issues of Endocrinology, Sphingomyelin and Yeast in her study of Sphingolipid. The Ceramidase study which covers Cancer research that intersects with HaCaT, UVB-induced apoptosis, Cell and LNCaP. Her Neutral Ceramidase study integrates concerns from other disciplines, such as Alkaline Ceramidase and Ceramidase activity.

Her most cited work include:

  • Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry (468 citations)
  • Ceramide 1-Phosphate Is a Direct Activator of Cytosolic Phospholipase A2 (290 citations)
  • Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid. (257 citations)

What are the main themes of her work throughout her whole career to date?

Ceramide, Sphingolipid, Biochemistry, Cancer research and Cell biology are her primary areas of study. Her Ceramide research incorporates themes from Cancer cell, Lipid signaling and Programmed cell death. The various areas that Alicja Bielawska examines in her Sphingolipid study include Cell growth, Internal medicine, Signal transduction, Stereochemistry and Mitochondrion.

Ceramidase, Neutral Ceramidase, Enzyme, Ceramidase activity and Ceramide kinase are the primary areas of interest in her Biochemistry study. Her study in Cancer research is interdisciplinary in nature, drawing from both Immunology, Cancer, Tumor progression and Cell killing. Her studies deal with areas such as Molecular biology, Ceramide synthase, Sphingomyelin and Bcl-2-associated X protein as well as Cell biology.

She most often published in these fields:

  • Ceramide (69.64%)
  • Sphingolipid (42.86%)
  • Biochemistry (36.61%)

What were the highlights of her more recent work (between 2015-2021)?

  • Ceramide (69.64%)
  • Cancer research (30.36%)
  • Sphingolipid (42.86%)

In recent papers she was focusing on the following fields of study:

Her primary areas of investigation include Ceramide, Cancer research, Sphingolipid, Acid Ceramidase and Cancer cell. Her Ceramide study focuses on Ceramidase in particular. Her Cancer research research incorporates elements of Tumor necrosis factor alpha, Tumor progression, Prostate cancer and Proto-oncogene tyrosine-protein kinase Src.

Sphingolipid is a subfield of Biochemistry that Alicja Bielawska explores. Her work on Lysosome, Cell growth, Fatty acid and Prodrug as part of general Biochemistry research is frequently linked to Fenretinide, thereby connecting diverse disciplines of science. Her work deals with themes such as Ceramidases, Immune system, Diastereomer, Growth inhibition and Enantiomer, which intersect with Acid Ceramidase.

Between 2015 and 2021, her most popular works were:

  • Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells. (40 citations)
  • Cytokine-induced release of ceramide-enriched exosomes as a mediator of cell death signaling in an oligodendroglioma cell line (36 citations)
  • Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression (29 citations)

In her most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Cancer

Her main research concerns Ceramide, Cell biology, Cancer research, Acid Ceramidase and Lysosome. Her Ceramide research integrates issues from Autophagy, Cell, Cathepsin D, Cathepsin and Myeloid-derived Suppressor Cell. Her Cell biology research incorporates themes from Cell type and Cytokine.

Her work carried out in the field of Cancer research brings together such families of science as Tumor necrosis factor alpha, Inflammation, Sphingosine-1-phosphate and Colitis. Her Acid Ceramidase study results in a more complete grasp of Biochemistry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

Jacek Bielawski;Zdzislaw M. Szulc;Yusuf A. Hannun;Alicja Bielawska.
Methods (2006)

728 Citations

Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid.

Charles E. Chalfant;Katsuya Kishikawa;Marc C. Mumby;Craig Kamibayashi.
Journal of Biological Chemistry (1999)

389 Citations

Ceramide 1-Phosphate Is a Direct Activator of Cytosolic Phospholipase A2

Benjamin J. Pettus;Alicja Bielawska;Preeti Subramanian;Dayanjan S. Wijesinghe.
Journal of Biological Chemistry (2004)

373 Citations

Molecular cloning and characterization of a human mitochondrial ceramidase.

Samer El Bawab;Patrick Roddy;Ting Qian;Alicja Bielawska.
Journal of Biological Chemistry (2000)

353 Citations

Blood sphingolipidomics in healthy humans: impact of sample collection methodology.

Samar M. Hammad;Jason S. Pierce;Farzan Soodavar;Kent J. Smith.
Journal of Lipid Research (2010)

303 Citations

Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release.

Benjamin J. Pettus;Alicja Bielawska;Sarah Spiegel;Patrick Roddy.
Journal of Biological Chemistry (2003)

286 Citations

Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity.

Cungui Mao;Ruijuan Xu;Alicja Bielawska;Lina M. Obeid.
Journal of Biological Chemistry (2000)

199 Citations

The structural requirements for ceramide activation of serine-threonine protein phosphatases

Charles E. Chalfant;Charles E. Chalfant;Zdzislaw Szulc;Patrick Roddy;Alicja Bielawska.
Journal of Lipid Research (2004)

185 Citations

Cloning and characterization of a Saccharomyces cerevisiae alkaline ceramidase with specificity for dihydroceramide.

Cungui Mao;Ruijuan Xu;Alicja Bielawska;Zdzislaw M. Szulc.
Journal of Biological Chemistry (2000)

185 Citations

Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide.

Cungui Mao;Ruijuan Xu;Zdzislaw M. Szulc;Alicja Bielawska.
Journal of Biological Chemistry (2001)

183 Citations

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