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Biology and Biochemistry

D-Index
76
Citations
17358
World Ranking
5130
National Ranking
2447

Overview

Alicja Bielawska is affiliated with the Medical University of South Carolina in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these areas, their work focuses on several subfields including Molecular Biology, Immunology, Pulmonary and Respiratory Medicine, Biomedical Engineering, and Hematology.

The main topics covered in Alicja Bielawska's research include:

  • Sphingolipid Metabolism and Signaling
  • Photodynamic Therapy Research Studies
  • Nanoplatforms for cancer theranostics
  • Immune Cell Function and Interaction
  • Platelet Disorders and Treatments
  • Immune cells in cancer
  • Drug Transport and Resistance Mechanisms

Alicja Bielawska has contributed to a number of scientific publications. Notable papers include:

  • Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis, 2020, Cytokine
  • Mechanistic insights into ceramidase inhibitor LCL521-enhanced tumor cell killing by photodynamic and thermal ablation therapies, 2020, Photochemical & Photobiological Sciences
  • Controlling Immunoregulatory Cell Activity for Effective Photodynamic Therapy of Cancer, 2022, Methods in molecular biology
  • Synthesis of erythro-B13 enantiomers and stereospecific action of full set of B13-isomers in MCF7 breast carcinoma cells: Cellular metabolism and effects on sphingolipids, 2021, Bioorganic & Medicinal Chemistry
  • Molecular Cloning and Characterization of a Human Mitochondrial Ceramidase, 2021, UNC Libraries

They have worked alongside frequent coauthors such as Zdzisław M. Szulc, Yusuf A. Hannun, Aiping Bai, Mladen Korbelik, and Dan Zhao. Their collaborative research has appeared in venues including Cytokine, Photochemical & Photobiological Sciences, Methods in molecular biology, Bioorganic & Medicinal Chemistry, and UNC Libraries.

Best Publications

  • Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

    Jacek Bielawski;Zdzislaw M. Szulc;Yusuf A. Hannun;Alicja Bielawska

  • Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

    T. Okazaki;A. Bielawska;R.M. Bell;Y.A. Hannun

  • Role for ceramide in cell cycle arrest

    Supriya Jayadev;Bin Liu;Alicja E. Bielawska;Joanna Y. Lee

  • Role of Ceramide in Cellular Senescence

    Mark E. Venable;Joanna Y. Lee;Miriam J. Smyth;Alicja Bielawska

  • Ceramide Activates the Stress-activated Protein Kinases

    John K. Westwick;Alicja E. Bielawska;Ghassan Dbaibo;Yusuf A. Hannun

  • Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity.

    Clifford G. Tepper;Supriya Jayadev;Bin Liu;Alicja Bielawska

  • Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid.

    Charles E. Chalfant;Katsuya Kishikawa;Marc C. Mumby;Craig Kamibayashi

  • Selectivity of Ceramide-mediated Biology. Lack of activity of erythro-DIHYDROCERAMIDE.

    A Bielawska;H M Crane;D Liotta;L M Obeid

  • Ceramide 1-Phosphate Is a Direct Activator of Cytosolic Phospholipase A2

    Benjamin J. Pettus;Alicja Bielawska;Preeti Subramanian;Dayanjan S. Wijesinghe

  • Blood sphingolipidomics in healthy humans: impact of sample collection methodology.

    Samar M. Hammad;Jason S. Pierce;Farzan Soodavar;Kent J. Smith

  • Molecular cloning and characterization of a human mitochondrial ceramidase.

    Samer El Bawab;Patrick Roddy;Ting Qian;Alicja Bielawska

  • Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction.

    Robert A. Wolff;Rick T. Dobrowsky;Alicja Bielawska;Lina M. Obeid

  • (1S,2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol as an Inhibitor of Ceramidase

    Alicja Bielawska;Mathew S. Greenberg;David Perry;Supriya Jayadev

  • Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release.

    Benjamin J. Pettus;Alicja Bielawska;Sarah Spiegel;Patrick Roddy

  • Characteristics and partial purification of a novel cytosolic, magnesium-independent, neutral sphingomyelinase activated in the early signal transduction of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

    T Okazaki;A Bielawska;N Domae;R M Bell

  • Involvement of Dihydroceramide Desaturase in Cell Cycle Progression in Human Neuroblastoma Cells

    Jacqueline M. Kraveka;Li Li;Zdzislaw M. Szulc;Jacek Bielawski

  • The human FA2H gene encodes a fatty acid 2-hydroxylase.

    Nathan L. Alderson;Barbara M. Rembiesa;Michael D. Walla;Alicja Bielawska

  • Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry.

    Jacek Bielawski;Jason S Pierce;Justin Snider;Barbara Rembiesa

  • Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity.

    Cungui Mao;Ruijuan Xu;Alicja Bielawska;Lina M. Obeid

  • The structural requirements for ceramide activation of serine-threonine protein phosphatases

    Charles E. Chalfant;Charles E. Chalfant;Zdzislaw Szulc;Patrick Roddy;Alicja Bielawska

Frequent Co-Authors

Jacek Bielawski
Jacek Bielawski Medical University of South Carolina
Yusuf A. Hannun
Yusuf A. Hannun Stony Brook University
Lina M. Obeid
Lina M. Obeid Stony Brook University
Charles E. Chalfant
Charles E. Chalfant Virginia Commonwealth University
Kebin Liu
Kebin Liu Augusta University
Marco Colombini
Marco Colombini University of Maryland, College Park
Besim Ogretmen
Besim Ogretmen Medical University of South Carolina
Robert Bittman
Robert Bittman City University of New York
Maria Trojanowska
Maria Trojanowska Boston University
Edward L. Hogan
Edward L. Hogan Medical University of South Carolina

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