What is he best known for?
The fields of study he is best known for:
Charles E. Chalfant spends much of his time researching Ceramide, Biochemistry, Lipid signaling, Cell biology and Ceramide kinase.
He combines subjects such as Tumor necrosis factor alpha, Cancer research, Enzyme activator, Sphingosine-1-phosphate and Protein phosphatase 1 with his study of Ceramide.
His research investigates the link between Protein phosphatase 1 and topics such as Molecular biology that cross with problems in Alternative splicing, Tyrosine phosphorylation, Heterogeneous ribonucleoprotein particle and Phosphorylation.
His specific area of interest is Biochemistry, where he studies Protein phosphatase 2.
Charles E. Chalfant interconnects Phospholipase A2 and Arachidonic acid in the investigation of issues within Ceramide kinase.
His Arachidonic acid research is multidisciplinary, incorporating perspectives in Calcium, Cytokine and Cytosol.
His most cited work include:
- Ceramide in apoptosis: an overview and current perspectives. (652 citations)
- Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling (362 citations)
- Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling (362 citations)
What are the main themes of his work throughout his whole career to date?
Charles E. Chalfant focuses on Biochemistry, Ceramide, Ceramide kinase, Cell biology and Lipid signaling.
The Phospholipase A2, Cytosol, In vitro and Vesicle research Charles E. Chalfant does as part of his general Biochemistry study is frequently linked to other disciplines of science, such as Dissociation constant, therefore creating a link between diverse domains of science.
His Ceramide study combines topics in areas such as Tumor necrosis factor alpha, Phosphatase, Protein phosphatase 1, Sphingolipid and Molecular biology.
The Ceramide kinase study combines topics in areas such as Ceramide transport, Calcium, Lipidomics and Eicosanoid.
His research integrates issues of Apoptosis, Arachidonic acid, Phospholipase A and Alternative splicing in his study of Cell biology.
The study incorporates disciplines such as Serine, Sphingosine-1-phosphate, Function, Proinflammatory cytokine and Macrophage in addition to Lipid signaling.
He most often published in these fields:
- Biochemistry (74.77%)
- Ceramide (64.86%)
- Ceramide kinase (63.06%)
What were the highlights of his more recent work (between 2015-2021)?
- Immunology (14.41%)
- Inflammation (16.22%)
- Sphingolipid (26.13%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Immunology, Inflammation, Sphingolipid, Ceramide and Endocrinology.
His Sphingolipid research incorporates themes from Aspirin, Hydroxyeicosatetraenoic acid and Prostacyclin.
His Ceramide research incorporates elements of Wound healing, Phospholipase A2 and Sphingomyelin.
His Nod research is multidisciplinary, incorporating elements of Arachidonic acid, Lipid signaling and Immune system.
Charles E. Chalfant studied NOD mice and Eicosanoid that intersect with Cell biology.
His Cell biology research is multidisciplinary, relying on both Proinflammatory cytokine and Molecular biology.
Between 2015 and 2021, his most popular works were:
- Anaplasma phagocytophilum Rab10‐dependent parasitism of the trans‐Golgi network is critical for completion of the infection cycle (18 citations)
- Lactic Acid Inhibits Lipopolysaccharide-Induced Mast Cell Function by Limiting Glycolysis and ATP Availability. (9 citations)
- Caspase-9b Interacts Directly with cIAP1 to Drive Agonist-Independent Activation of NF-κB and Lung Tumorigenesis. (6 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Pharmacology, Inflammation, Molecular biology, NF-κB and Caspase.
His Pharmacology study combines topics from a wide range of disciplines, such as Glycolysis, Lipopolysaccharide, Cytokine and Sepsis.
He has included themes like Mast cell, Serine C-palmitoyltransferase and Glucose uptake in his Inflammation study.
Charles E. Chalfant combines Molecular biology and Ubiquitin ligase in his research.
His NF-κB study integrates concerns from other disciplines, such as Cancer research and Cell growth.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
