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Charles E. Chalfant

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
11772
World Ranking
13834
National Ranking
5851

Charles E. Chalfant publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Charles E. Chalfant sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 250 publications — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Charles E. Chalfant D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Charles E. Chalfant sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 57 D-Index — 31st percentile

31% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Charles E. Chalfant is affiliated with Virginia Commonwealth University in the United States. Their research primarily covers the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a total of 68 publications in the former and 60 in the latter. Among subfields, they have contributed extensively to Molecular Biology, Genetics, Physiology, Surgery, and Endocrinology, Diabetes and Metabolism.

Their main research topics include Sphingolipid Metabolism and Signaling, Pancreatic function and diabetes, Diabetes and associated disorders, Acute Myeloid Leukemia Research, Lipid Membrane Structure and Behavior, Cancer-related molecular mechanisms research, and RNA modifications and cancer.

Chalfant has published frequently in several venues, with notable repeat appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetes
  • Molecular Neurobiology
  • Journal of Lipid Research
  • Science Signaling

Among recent research papers, the following are highlighted for their topics and venues:

  • Ceramide Kinase Inhibition Drives Ferroptosis and Sensitivity to Cisplatin in Mutant KRAS Lung Cancer by Dysregulating VDAC-Mediated Mitochondria Function, 2022, Molecular Cancer Research
  • Emerging roles for human glycolipid transfer protein superfamily members in the regulation of autophagy, inflammation, and cell death, 2020, Progress in Lipid Research
  • Sphingosine-1-phosphate interactions in the spleen and heart reflect extent of cardiac repair in mice and failing human hearts, 2021, American Journal of Physiology-Heart and Circulatory Physiology
  • Lipid mediators and biomarkers associated with type 1 diabetes development, 2020, JCI Insight
  • Meibum sphingolipid composition is altered in individuals with meibomian gland dysfunction-a side by side comparison of Meibum and Tear Sphingolipids, 2021, The Ocular Surface

Collaborations have been consistent with several researchers, including:

  • Daniel Stephenson
  • Nawajes Mandal
  • H. Patrick MacKnight
  • Sasanka Ramanadham
  • Xiujie Xie

Best Publications

  • Ceramide in apoptosis: an overview and current perspectives.

    Benjamin J. Pettus;Charles E. Chalfant;Yusuf A. Hannun

  • Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling

    Charles E. Chalfant;Charles E. Chalfant;Sarah Spiegel

  • Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid.

    Charles E. Chalfant;Katsuya Kishikawa;Marc C. Mumby;Craig Kamibayashi

  • Ceramide 1-Phosphate Is a Direct Activator of Cytosolic Phospholipase A2

    Benjamin J. Pettus;Alicja Bielawska;Preeti Subramanian;Dayanjan S. Wijesinghe

  • De Novo Ceramide Regulates the Alternative Splicing of Caspase 9 and Bcl-x in A549 Lung Adenocarcinoma Cells DEPENDENCE ON PROTEIN PHOSPHATASE-1

    Charles E. Chalfant;Kristin Rathman;Ryan L. Pinkerman;Rachel E. Wood

  • The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-α

    Benjamin J. Pettus;Jacek Bielawski;Anna M. Porcelli;Davis L. Reames

  • The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x

    Maria Paola Paronetto;Tilman Achsel;Autumn Massiello;Autumn Massiello;Charles E. Chalfant;Charles E. Chalfant

  • Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release.

    Benjamin J. Pettus;Alicja Bielawska;Sarah Spiegel;Patrick Roddy

  • Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

    Dhirendra K. Simanshu;Ravi Kanth Kamlekar;Dayanjan S. Wijesinghe;Xianqiong Zou

  • Mechanism of Apoptosis Induced by the Inhibition of Fatty Acid Synthase in Breast Cancer Cells

    Sucharita Bandyopadhyay;Rui Zhan;Ying Wang;Sudha K. Pai

  • Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide

    Léon J. A. Spijkers;Rob F. P. van den Akker;Ben J. A. Janssen;Jacques J. Debets

  • The structural requirements for ceramide activation of serine-threonine protein phosphatases

    Charles E. Chalfant;Charles E. Chalfant;Zdzislaw Szulc;Patrick Roddy;Alicja Bielawska

  • FAS Activation Induces Dephosphorylation of SR Proteins DEPENDENCE ON THE DE NOVO GENERATION OF CERAMIDE AND ACTIVATION OF PROTEIN PHOSPHATASE 1

    Charles E. Chalfant;Besim Ogretmen;Sehamuddin Galadari;Bart Jan Kroesen

  • Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy Secondary to Pulmonary Arterial Hypertension

    Jose Gomez-Arroyo;Shiro Mizuno;Karol Szczepanek;Benjamin Van Tassell

  • The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors.

    Shawn G. Payne;Carole A. Oskeritzian;Rachael Griffiths;Preeti Subramanian

  • Sphingolipids in Inflammation: Roles and Implications

    B. J. Pettus;C. E. Chalfant;Y. A. Hannun

  • The coordination of prostaglandin E2 production by sphingosine-1-phosphate and ceramide-1-phosphate.

    Benjamin James Pettus;Kazuyuki Kitatani;Charles E. Chalfant;Tarek A. Taha

  • Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a

    Jacqueline C. Shultz;Rachel W. Goehe;D. Shanaka Wijesinghe;Charuta Murudkar

  • Ceramide 1-Phosphate Acts as a Positive Allosteric Activator of Group IVA Cytosolic Phospholipase A2α and Enhances the Interaction of the Enzyme with Phosphatidylcholine

    Preeti Subramanian;Robert V. Stahelin;Zdzislaw Szulc;Alicja Bielawska

  • Ceramide-1-phosphate binds group IVA cytosolic phospholipase a2 via a novel site in the C2 domain.

    Robert V. Stahelin;Preeti Subramanian;Mohsin Vora;Wonhwa Cho

Frequent Co-Authors

Yusuf A. Hannun
Yusuf A. Hannun Stony Brook University
Robert V. Stahelin
Robert V. Stahelin Purdue University West Lafayette
Alicja Bielawska
Alicja Bielawska Medical University of South Carolina
Lina M. Obeid
Lina M. Obeid Stony Brook University
Sasanka Ramanadham
Sasanka Ramanadham University of Alabama at Birmingham
Sarah Spiegel
Sarah Spiegel Virginia Commonwealth University
Jeremy C. Allegood
Jeremy C. Allegood Virginia Commonwealth University
Rhoderick E. Brown
Rhoderick E. Brown University of Minnesota
John J. Ryan
John J. Ryan Virginia Commonwealth University
Wonhwa Cho
Wonhwa Cho University of Illinois at Chicago

External Links

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Related Online Degrees & Career Pathways

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Best Scientists Citing Charles E. Chalfant

Yusuf A. Hannun

Yusuf A. Hannun

Stony Brook University

Publications: 112

Lina M. Obeid

Lina M. Obeid

Stony Brook University

Publications: 96

Jacek Bielawski

Jacek Bielawski

Medical University of South Carolina

Publications: 32

Claudio Sette

Claudio Sette

Catholic University of the Sacred Heart

Publications: 32

Besim Ogretmen

Besim Ogretmen

Medical University of South Carolina

Publications: 31

Sarah Spiegel

Sarah Spiegel

Virginia Commonwealth University

Publications: 28

Yasuyuki Igarashi

Yasuyuki Igarashi

Hokkaido University

Publications: 23

Robert V. Stahelin

Robert V. Stahelin

Purdue University West Lafayette

Publications: 23

Alicja Bielawska

Alicja Bielawska

Medical University of South Carolina

Publications: 22

Alfred H. Merrill

Alfred H. Merrill

Georgia Institute of Technology

Publications: 21

Robert Bittman

Robert Bittman

City University of New York

Publications: 21

Benoit Chabot

Benoit Chabot

Université de Sherbrooke

Publications: 20

Sheldon Milstien

Sheldon Milstien

Virginia Commonwealth University

Publications: 18

Andreas Billich

Andreas Billich

Novartis (Switzerland)

Publications: 17

Rhoderick E. Brown

Rhoderick E. Brown

University of Minnesota

Publications: 16

Erich Gulbins

Erich Gulbins

University of Duisburg-Essen

Publications: 16

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