D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 79 Citations 20,617 295 World Ranking 2725 National Ranking 175

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Biochemistry

Yasuyuki Igarashi mainly focuses on Biochemistry, Sphingosine, Cell biology, Sphingosine-1-phosphate and Ceramide. His Biochemistry and Sphingolipid, Lipid signaling, Ceramide synthase, Signal transduction and Endoplasmic reticulum investigations all form part of his Biochemistry research activities. His study in Sphingosine is interdisciplinary in nature, drawing from both Platelet activation, Platelet, Lysophosphatidic acid and Kinase activity.

His study in the field of Extracellular, Intracellular and Protein kinase C is also linked to topics like Exosome. His research in Sphingosine-1-phosphate intersects with topics in Lyase activity, Motility, Second messenger system and Cytosol. His Ceramide research incorporates elements of Molecular biology, Lipid metabolism and Sphingomyelin.

His most cited work include:

  • International Union of Pharmacology. XXXIV. Lysophospholipid Receptor Nomenclature (431 citations)
  • Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum (416 citations)
  • Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets (400 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Biochemistry, Cell biology, Sphingosine, Ceramide and Sphingolipid. His Biochemistry research is multidisciplinary, relying on both Platelet and Molecular biology. His Cell biology study frequently draws parallels with other fields, such as Cell growth.

His Sphingosine research focuses on Platelet activation and how it relates to Lysophosphatidic acid. His Ceramide research integrates issues from Endocrinology, Lipid signaling and Sphingomyelin. The Sphingolipid study combines topics in areas such as Internal medicine and Cell signaling.

He most often published in these fields:

  • Biochemistry (46.62%)
  • Cell biology (39.55%)
  • Sphingosine (36.01%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (39.55%)
  • Ceramide (25.72%)
  • Sphingolipid (22.51%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cell biology, Ceramide, Sphingolipid, Biochemistry and Sphingomyelin. His work in the fields of Cell biology, such as Phosphorylation, intersects with other areas such as Exosome. His Ceramide research is multidisciplinary, incorporating perspectives in Internal medicine, Cell migration, Endocrinology and Transmembrane protein.

His Sphingolipid research incorporates themes from Lipid signaling, Sphingosine, Lipidomics, Glucosylceramides and Combinatorial chemistry. His Biochemistry study combines topics in areas such as Molecular biology, ABO blood group system and Amyloid. Yasuyuki Igarashi has researched Sphingomyelin in several fields, including Inflammation, Mass spectrometry imaging, Metabolism and Keratinocyte.

Between 2013 and 2021, his most popular works were:

  • Decreased Amyloid-β Pathologies by Intracerebral Loading of Glycosphingolipid-enriched Exosomes in Alzheimer Model Mice (141 citations)
  • A potential function for neuronal exosomes: Sequestering intracerebral amyloid‐β peptide (135 citations)
  • Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults. (76 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

Yasuyuki Igarashi spends much of his time researching Ceramide, Cell biology, Biochemistry, Sphingomyelin and Sphingolipid. His Ceramide research is multidisciplinary, incorporating elements of Endocrinology and Internal medicine. His Cell biology research includes elements of In vitro and Cell migration.

His Biochemistry research focuses on Structure–activity relationship, GPR120, Activator, IC50 and Receptor. His work carried out in the field of Sphingomyelin brings together such families of science as Inflammation, Mass spectrometry imaging and Metabolism. Yasuyuki Igarashi interconnects Glycome and Glycomics in the investigation of issues within Sphingolipid.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum

Yutaka Yatomi;Yasuyuki Igarashi;Libo Yang;Nobuo Hisano.
Journal of Biochemistry (1997)

636 Citations

Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets

Yutaka Yatomi;Fuqiang Ruan;Sen-itiroh Hakomori;Yasuyuki Igarashi.
Blood (1995)

612 Citations

International Union of Pharmacology. XXXIV. Lysophospholipid Receptor Nomenclature

Jerold Chun;Edward J. Goetzl;Timothy Hla;Yasuyuki Igarashi.
Pharmacological Reviews (2002)

597 Citations

Functional Role of Glycosphingolipids in Cell Recognition and Signaling

Sen-itiroh Hakomori;Yasuyuki Igarashi.
Journal of Biochemistry (1995)

535 Citations

Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia

Kohei Yuyama;Hui Sun;Susumu Mitsutake;Yasuyuki Igarashi.
Journal of Biological Chemistry (2012)

499 Citations

Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.

Yusuke Ohno;Akio Kihara;Takamitsu Sano;Yasuyuki Igarashi.
Biochimica et Biophysica Acta (2006)

487 Citations

Mammalian Lass6 and its related family members regulate synthesis of specific ceramides

Yukiko Mizutani;Akio Kihara;Yasuyuki Igarashi.
Biochemical Journal (2005)

431 Citations

Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance.

Kazuya Kabayama;Takashige Sato;Kumiko Saito;Nicoletta Loberto.
Proceedings of the National Academy of Sciences of the United States of America (2007)

400 Citations

Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities.

Yasuyuki Igarashi;Senitiroh Hakomori;Tatsushi Toyokuni;Barbara Dean.
Biochemistry (1989)

385 Citations

Ganglioside GM3 Participates in the Pathological Conditions of Insulin Resistance

Seiichi Tagami;Jin-ichi Inokuchi;Kazuya Kabayama;Haruhiko Yoshimura.
Journal of Biological Chemistry (2002)

382 Citations

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