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Yasuyuki Igarashi

Yasuyuki Igarashi

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
23770
World Ranking
3339
National Ranking
206

Overview

Yasuyuki Igarashi is affiliated with Hokkaido University in Japan and has a research focus spanning biochemistry, genetics, molecular biology, and engineering. Their work contributes to multiple subfields including molecular biology, electrical and electronic engineering, physiology, plant science, and pharmaceutical science.

The scientist's research mainly addresses topics such as sphingolipid metabolism and signaling, silicon carbide semiconductor technologies, silicon and solar cell technologies, lipid membrane structure and behavior, semiconductor materials and devices, extracellular vesicles in disease, and advancements in transdermal drug delivery.

Yasuyuki Igarashi has published extensively in various academic venues. Frequent publication venues include:

  • Defect and diffusion forum/Diffusion and defect data, solid state data. Part A, Defect and diffusion forum
  • International Journal of Molecular Sciences
  • Advanced Biosystems
  • Journal of The Japanese Institute of Landscape Architecture
  • Diffusion and defect data, solid state data. Part B, Solid state phenomena/Solid state phenomena

Notable recent papers by Igarashi and collaborators cover diverse topics related to biochemistry and molecular biology:

  • Lysosomal-associated transmembrane protein 4B regulates ceramide-induced exosome release, 2020, The FASEB Journal
  • Ceramide Metabolism Regulated by Sphingomyelin Synthase 2 Is Associated with Acquisition of Chemoresistance via Exosomes in Human Leukemia Cells, 2022, International Journal of Molecular Sciences
  • Blood-brain barrier permeability analysis of plant ceramides, 2020, PLoS ONE
  • Linking glycosphingolipids to Alzheimer's amyloid-ß: extracellular vesicles and functional plant materials, 2022, Glycoconjugate Journal
  • Evaluation of Plant Ceramide Species-Induced Exosome Release from Neuronal Cells and Exosome Loading Using Deuterium Chemistry, 2022, International Journal of Molecular Sciences

Igarashi frequently collaborates with a group of coauthors including Kohei Yuyama, Daisuke Mikami, Kazumi Takano, Yohsuke Matsushita, and Katsuyuki Mukai. The collaborations reflect a multidisciplinary approach, bridging molecular biology with materials science and engineering.

Best Publications

  • Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia

    Kohei Yuyama;Hui Sun;Susumu Mitsutake;Yasuyuki Igarashi

  • Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum

    Yutaka Yatomi;Yasuyuki Igarashi;Libo Yang;Nobuo Hisano

  • Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets

    Yutaka Yatomi;Fuqiang Ruan;Sen-itiroh Hakomori;Yasuyuki Igarashi

  • International Union of Pharmacology. XXXIV. Lysophospholipid Receptor Nomenclature

    Jerold Chun;Edward J. Goetzl;Timothy Hla;Yasuyuki Igarashi

  • Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.

    Yusuke Ohno;Akio Kihara;Takamitsu Sano;Yasuyuki Igarashi

  • Functional Role of Glycosphingolipids in Cell Recognition and Signaling

    Sen-itiroh Hakomori;Yasuyuki Igarashi

  • Mammalian Lass6 and its related family members regulate synthesis of specific ceramides

    Yukiko Mizutani;Akio Kihara;Yasuyuki Igarashi

  • Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance.

    Kazuya Kabayama;Takashige Sato;Kumiko Saito;Nicoletta Loberto

  • Ganglioside GM3 Participates in the Pathological Conditions of Insulin Resistance

    Seiichi Tagami;Jin-ichi Inokuchi;Kazuya Kabayama;Haruhiko Yoshimura

  • Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities.

    Yasuyuki Igarashi;Senitiroh Hakomori;Tatsushi Toyokuni;Barbara Dean

  • ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis

    Yusuke Ohno;Shota Suto;Masao Yamanaka;Yukiko Mizutani

  • Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood.

    Takamitsu Sano;Daniel L. Baker;Tamas Virag;Atsushi Wada

  • Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction.

    K E Bornfeldt;L M Graves;E W Raines;Y Igarashi

  • Ceramide biosynthesis in keratinocyte and its role in skin function.

    Yukiko Mizutani;Susumu Mitsutake;Kiyomi Tsuji;Akio Kihara

  • Decreased Amyloid-β Pathologies by Intracerebral Loading of Glycosphingolipid-enriched Exosomes in Alzheimer Model Mice

    Kohei Yuyama;Hui Sun;Shota Sakai;Susumu Mitsutake

  • Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness.

    Yoshito Sadahira;Fuqiang Ruan;Sen-Itiroh Hakomori;Yasuyuki Igarashi

  • Induction of Apoptosis by Sphingosine in Human Leukemic HL-60 Cells: A Possible Endogenous Modulator of Apoptotic DNA Fragmentation Occurring during Phorbol Ester-induced Differentiation

    Hideki Ohta;Elizabeth A. Sweeney;Atsushi Masamune;Yutaka Yatomi

  • Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid.

    Yutaka Yatomi;Soichiro Yamamura;Fuqiang Ruan;Yasuyuki Igarashi

  • Sphingosine 1-phosphate: synthesis and release.

    Yatomi Y;Ozaki Y;Ohmori T;Igarashi Y

  • Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells.

    Yutaka Yatomi;Tsukasa Ohmori;Tsukasa Ohmori;Ge Rile;Ge Rile;Fuminori Kazama;Fuminori Kazama

Frequent Co-Authors

Akio Kihara
Akio Kihara Hokkaido University
Sen-itiroh Hakomori
Sen-itiroh Hakomori Pacific Northwest Diabetes Research Institute
Yutaka Yatomi
Yutaka Yatomi University of Tokyo
Yukio Ozaki
Yukio Ozaki University of Yamanashi
Gabor Tigyi
Gabor Tigyi University of Tennessee Health Science Center
Tomohiro Tamura
Tomohiro Tamura National Institute of Advanced Industrial Science and Technology
Yoshikazu Tanaka
Yoshikazu Tanaka Tohoku University
Atsushi Masamune
Atsushi Masamune Tohoku University
Yoshinori Hasegawa
Yoshinori Hasegawa Nagoya University

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