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D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
34465
World Ranking
8437
National Ranking
562

Overview

Akio Kihara is affiliated with Hokkaido University in Japan and has a research focus spanning biochemistry, genetics, molecular biology, and medicine. Their work contributes to various subfields including molecular biology, cell biology, pharmaceutical science, biochemistry, and public health, environmental and occupational health.

Their research encompasses a range of topics, notably advancements in transdermal drug delivery, skin and cellular biology research, lipid membrane structure and behavior, sphingolipid metabolism and signaling, lipid metabolism and biosynthesis, ocular surface and contact lens studies, and dermatology and skin diseases.

Frequent coauthors in their collaborations include:

  • Takayuki Sassa
  • Yusuke Ohno
  • Masatoshi Miyamoto
  • Keisuke Jojima
  • Kento Otsuka

Akio Kihara has published extensively in several scientific journals. The most common publication venues include:

  • Journal of Lipid Research
  • Journal of Biological Chemistry
  • Journal of Dermatological Science
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife

Among their recent papers are:

  • "Comparative profiling and comprehensive quantification of stratum corneum ceramides in humans and mice by LC/MS/MS" (2020, Journal of Lipid Research)
  • "Whole picture of human stratum corneum ceramides, including the chain-length diversity of long-chain bases" (2022, Journal of Lipid Research)
  • "Skin permeability barrier formation by the ichthyosis-causative gene FATP4 through formation of the barrier lipid ω- O -acylceramide" (2020, Proceedings of the National Academy of Sciences)
  • "Biosynthesis of the anti-lipid-microdomain sphingoid base 4,14-sphingadiene by the ceramide desaturase FADS3" (2020, The FASEB Journal)
  • "Lipid polarity gradient formed by ω-hydroxy lipids in tear film prevents dry eye disease" (2020, eLife)

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae.

    Akio Kihara;Takeshi Noda;Naotada Ishihara;Yoshinori Ohsumi

  • Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network.

    Akio Kihara;Yukiko Kabeya;Yoshinori Ohsumi;Tamotsu Yoshimori

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.

    Yusuke Ohno;Akio Kihara;Takamitsu Sano;Yasuyuki Igarashi

  • Mammalian Lass6 and its related family members regulate synthesis of specific ceramides

    Yukiko Mizutani;Akio Kihara;Yasuyuki Igarashi

  • Very long-chain fatty acids: elongation, physiology and related disorders

    Akio Kihara

  • Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion.

    Naotada Ishihara;Maho Hamasaki;Sadaki Yokota;Kuninori Suzuki

  • ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis

    Yusuke Ohno;Shota Suto;Masao Yamanaka;Yukiko Mizutani

  • FtsH is required for proteolytic elimination of uncomplexed forms of SecY, an essential protein translocase subunit.

    Akio Kihara;Yoshinori Akiyama;Koreaki Ito

  • Ceramide biosynthesis in keratinocyte and its role in skin function.

    Yukiko Mizutani;Susumu Mitsutake;Kiyomi Tsuji;Akio Kihara

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Metabolism of very long-chain Fatty acids: genes and pathophysiology.

    Takayuki Sassa;Akio Kihara

  • Identification and Characterization of a Novel Human Sphingosine-1-phosphate Phosphohydrolase, hSPP2

    Chie Ogawa;Akio Kihara;Maiko Gokoh;Yasuyuki Igarashi

  • Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate.

    Akio Kihara;Susumu Mitsutake;Yukiko Mizutani;Yasuyuki Igarashi

  • Synthesis and degradation pathways, functions, and pathology of ceramides and epidermal acylceramides.

    Akio Kihara

  • LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity

    Yukiko Mizutani;Akio Kihara;Yasuyuki Igarashi

  • Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes

    Kiyoharu Ito;Yoshihiro Anada;Motohiro Tani;Mika Ikeda

  • FtsH (HflB) is an ATP-dependent protease selectively acting on SecY and some other membrane proteins.

    Yoshinori Akiyama;Akio Kihara;Hajime Tokuda;Koreaki Ito

Frequent Co-Authors

Yasuyuki Igarashi
Yasuyuki Igarashi Hokkaido University
Koreaki Ito
Koreaki Ito Kyoto Sangyo University
Yoshinori Akiyama
Yoshinori Akiyama Kyoto University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Tamotsu Yoshimori
Tamotsu Yoshimori Osaka University
Takeshi Noda
Takeshi Noda Osaka University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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