World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
112
Citations
44389
World Ranking
819
National Ranking
498

Biology and Biochemistry

D-Index
114
Citations
46412
World Ranking
837
National Ranking
523

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Lina M. Obeid was affiliated with Stony Brook University in the United States. Their research focused primarily on biochemistry, genetics, and molecular biology, with significant contributions to medicine. The subfields most represented in their work included molecular biology, immunology, cell biology, physiology, and biochemistry.

Obeid's scientific work centered on several major topics, notably:

  • Sphingolipid metabolism and signaling
  • Endoplasmic reticulum stress and disease
  • Immune cells in cancer
  • Cellular transport and secretion
  • Lipid membrane structure and behavior
  • Lysosomal storage disorders research
  • Autophagy in disease and therapy

Their recent publications reflected these areas of study, including:

  • "Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α" (2020, Scientific Reports)
  • "Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells" (2021, Scientific Reports)
  • "GRASP55 regulates intra-Golgi localization of glycosylation enzymes to control glycosphingolipid biosynthesis" (2021, The EMBO Journal)
  • "Ceramide launches an acute anti-adhesion pro-migration cell signaling program in response to chemotherapy" (2020, The FASEB Journal)
  • "Transcriptional Regulation of Sphingosine Kinase 1" (2020, Cells)

Obeid collaborated frequently with several researchers, including Yusuf A. Hannun (28 publications), Ashley J. Snider (14 publications), Fatema Al-Rashed (6 publications), Fahd Al-Mulla (6 publications), and Rasheed Ahmad (6 publications).

Their research was published in a variety of scientific journals. The most frequent venues included:

  • The FASEB Journal (5 publications)
  • Journal of Lipid Research (3 publications)
  • Scientific Reports (2 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (2 publications)
  • PLoS ONE (2 publications)

During their career, this scientist was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2004.

Best Publications

  • Principles of bioactive lipid signalling: lessons from sphingolipids

    Yusuf A. Hannun;Lina M. Obeid;Lina M. Obeid

  • Programmed cell death induced by ceramide

    Lina M. Obeid;Corinne M. Linardic;Linda A. Karolak;Yusuf A. Hannun

  • Sphingolipids and their metabolism in physiology and disease.

    Yusuf A. Hannun;Lina M. Obeid;Lina M. Obeid

  • An overview of sphingolipid metabolism: from synthesis to breakdown.

    Christopher R. Gault;Lina M. Obeid;Yusuf A. Hannun

  • The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind.

    Yusuf A. Hannun;Lina M. Obeid

  • Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.

    Mie-Young Kim;C. Linardic;L. Obeid;Y. Hannun

  • CERAMIDE : AN INTRACELLULAR SIGNAL FOR APOPTOSIS

    Yusuf A. Hannun;Lina M. Obeid

  • Role for ceramide in cell cycle arrest

    Supriya Jayadev;Bin Liu;Alicja E. Bielawska;Joanna Y. Lee

  • Role of Ceramide in Cellular Senescence

    Mark E. Venable;Joanna Y. Lee;Miriam J. Smyth;Alicja Bielawska

  • Ceramide synthases at the centre of sphingolipid metabolism and biology

    Thomas D. Mullen;Yusuf A. Hannun;Lina M. Obeid;Lina M. Obeid

  • Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

    Jerry E. Chipuk;Gavin P. McStay;Archana Bharti;Tomomi Kuwana

  • Thioredoxin Peroxidase Is a Novel Inhibitor of Apoptosis with a Mechanism Distinct from That of Bcl-2

    Ping Zhang;Bin Liu;San Won Kang;Min Seok Seo

  • Ceramidases : regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1 -phosphate

    Cungui Mao;Lina M. Obeid

  • Glutathione Regulation of Neutral Sphingomyelinase in Tumor Necrosis Factor-α-induced Cell Death

    Bin Liu;Nathalie Andrieu-Abadie;Thierry Levade;Ping Zhang

  • PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA).

    Korey R. Johnson;Kevin P. Becker;Maria Marta Facchinetti;Yusuf A. Hannun

  • Inhibition of Tumor Necrosis Factor-induced Cell Death in MCF7 by a Novel Inhibitor of Neutral Sphingomyelinase

    Chiara Luberto;Daniel F. Hassler;Paola Signorelli;Yasuo Okamoto

  • Selectivity of Ceramide-mediated Biology. Lack of activity of erythro-DIHYDROCERAMIDE.

    A Bielawska;H M Crane;D Liotta;L M Obeid

  • A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death

    Tarek A. Taha;Thomas D. Mullen;Lina M. Obeid

  • De Novo Ceramide Regulates the Alternative Splicing of Caspase 9 and Bcl-x in A549 Lung Adenocarcinoma Cells DEPENDENCE ON PROTEIN PHOSPHATASE-1

    Charles E. Chalfant;Kristin Rathman;Ryan L. Pinkerman;Rachel E. Wood

  • Bcl-2 interrupts the ceramide-mediated pathway of cell death.

    Jiandi Zhang;Nejemie Alter;John C. Reed;Christoph Borner

Frequent Co-Authors

Yusuf A. Hannun
Yusuf A. Hannun Stony Brook University
Jacek Bielawski
Jacek Bielawski Medical University of South Carolina
Alicja Bielawska
Alicja Bielawska Medical University of South Carolina
Besim Ogretmen
Besim Ogretmen Medical University of South Carolina
Gerard C. Blobe
Gerard C. Blobe Duke University
Charles E. Chalfant
Charles E. Chalfant Virginia Commonwealth University
Irina Petrache
Irina Petrache University of Cambridge
Louis M. Luttrell
Louis M. Luttrell Medical University of South Carolina
Vincent W. Yang
Vincent W. Yang Stony Brook University
Stuart M. Pitson
Stuart M. Pitson University of South Australia

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